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352 related items for PubMed ID: 18541621

  • 21. A 3D QSAR model of 17beta-HSD1 inhibitors based on a thieno[2,3-d]pyrimidin-4(3H)-one core applying molecular dynamics simulations and ligand-protein docking.
    Karkola S, Lilienkampf A, Wähälä K.
    ChemMedChem; 2008 Mar; 3(3):461-72. PubMed ID: 18224704
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  • 25. Steroidal lactones as inhibitors of 17beta-hydroxysteroid dehydrogenase type 5: chemical synthesis, enzyme inhibitory activity, and assessment of estrogenic and androgenic activities.
    Bydal P, Luu-The V, Labrie F, Poirier D.
    Eur J Med Chem; 2009 Feb; 44(2):632-44. PubMed ID: 18472187
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  • 27. Structure and function of human 17beta-hydroxysteroid dehydrogenases.
    Lukacik P, Kavanagh KL, Oppermann U.
    Mol Cell Endocrinol; 2006 Mar 27; 248(1-2):61-71. PubMed ID: 16414178
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  • 31. Substituted 6-phenyl-2-naphthols. Potent and selective nonsteroidal inhibitors of 17beta-hydroxysteroid dehydrogenase type 1 (17beta-HSD1): design, synthesis, biological evaluation, and pharmacokinetics.
    Marchais-Oberwinkler S, Kruchten P, Frotscher M, Ziegler E, Neugebauer A, Bhoga U, Bey E, Müller-Vieira U, Messinger J, Thole H, Hartmann RW.
    J Med Chem; 2008 Aug 14; 51(15):4685-98. PubMed ID: 18630892
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  • 32. Focused libraries of 16-substituted estrone derivatives and modified e-ring steroids: inhibitors of 17beta-hydroxysteroid dehydrogenase type 1.
    Vicker N, Lawrence HR, Allan GM, Bubert C, Smith A, Tutill HJ, Purohit A, Day JM, Mahon MF, Reed MJ, Potter BV.
    ChemMedChem; 2006 Apr 14; 1(4):464-81. PubMed ID: 16892382
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  • 34. Relative involvement of three 17beta-hydroxysteroid dehydrogenases (types 1, 7 and 12) in the formation of estradiol in various breast cancer cell lines using selective inhibitors.
    Laplante Y, Rancourt C, Poirier D.
    Mol Cell Endocrinol; 2009 Mar 25; 301(1-2):146-53. PubMed ID: 18812208
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  • 36. Pharmacophore modelling of 17beta-HSD1 enzyme based on active inhibitors and enzyme structure.
    Karkola S, Alho-Richmond S, Wahala K.
    Mol Cell Endocrinol; 2009 Mar 25; 301(1-2):225-8. PubMed ID: 18822344
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  • 38. Mammalian lignans and genistein decrease the activities of aromatase and 17beta-hydroxysteroid dehydrogenase in MCF-7 cells.
    Brooks JD, Thompson LU.
    J Steroid Biochem Mol Biol; 2005 Apr 25; 94(5):461-7. PubMed ID: 15876411
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  • 39. Design and synthesis of bisubstrate inhibitors of type 1 17beta-hydroxysteroid dehydrogenase: overview and perspectives.
    Fournier D, Poirier D, Mazumdar M, Lin SX.
    Eur J Med Chem; 2008 Nov 25; 43(11):2298-306. PubMed ID: 18372081
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