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331 related items for PubMed ID: 18544564

  • 1. Hypoxia-inducible factor-2alpha regulates the expression of TRAIL receptor DR5 in renal cancer cells.
    Mahajan S, Dammai V, Hsu T, Kraft AS.
    Carcinogenesis; 2008 Sep; 29(9):1734-41. PubMed ID: 18544564
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  • 2. Physapubescin selectively induces apoptosis in VHL-null renal cell carcinoma cells through down-regulation of HIF-2α and inhibits tumor growth.
    Chen L, Xia G, Qiu F, Wu C, Denmon AP, Zi X.
    Sci Rep; 2016 Sep 01; 6():32582. PubMed ID: 27581364
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  • 3. Up-regulation of hypoxia-inducible factors HIF-1alpha and HIF-2alpha under normoxic conditions in renal carcinoma cells by von Hippel-Lindau tumor suppressor gene loss of function.
    Krieg M, Haas R, Brauch H, Acker T, Flamme I, Plate KH.
    Oncogene; 2000 Nov 16; 19(48):5435-43. PubMed ID: 11114720
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  • 4. HIF-2alpha promotes hypoxic cell proliferation by enhancing c-myc transcriptional activity.
    Gordan JD, Bertout JA, Hu CJ, Diehl JA, Simon MC.
    Cancer Cell; 2007 Apr 16; 11(4):335-47. PubMed ID: 17418410
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  • 5. The opposing effect of hypoxia-inducible factor-2alpha on expression of telomerase reverse transcriptase.
    Lou F, Chen X, Jalink M, Zhu Q, Ge N, Zhao S, Fang X, Fan Y, Björkholm M, Liu Z, Xu D.
    Mol Cancer Res; 2007 Aug 16; 5(8):793-800. PubMed ID: 17699105
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  • 9. Differential regulation of LncRNA-SARCC suppresses VHL-mutant RCC cell proliferation yet promotes VHL-normal RCC cell proliferation via modulating androgen receptor/HIF-2α/C-MYC axis under hypoxia.
    Zhai W, Sun Y, Jiang M, Wang M, Gasiewicz TA, Zheng J, Chang C.
    Oncogene; 2016 Sep 15; 35(37):4866-80. PubMed ID: 26973243
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  • 10. Role of hypoxia-inducible factor (HIF)-1alpha versus HIF-2alpha in the regulation of HIF target genes in response to hypoxia, insulin-like growth factor-I, or loss of von Hippel-Lindau function: implications for targeting the HIF pathway.
    Carroll VA, Ashcroft M.
    Cancer Res; 2006 Jun 15; 66(12):6264-70. PubMed ID: 16778202
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  • 11. [The expression of hypoxia inducible factor-1,2 alpha in sporadic clear cell renal cell carcinoma and their relationships to the mutations of von Hippel-Lindau gene].
    Gong K, Zhang N, Na X, Wu G, Yang XY, Xin DQ, Na YQ.
    Zhonghua Wai Ke Za Zhi; 2005 Mar 15; 43(6):390-3. PubMed ID: 15854350
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  • 12. PTEN suppression of YY1 induces HIF-2 activity in von-Hippel-Lindau-null renal-cell carcinoma.
    Petrella BL, Brinckerhoff CE.
    Cancer Biol Ther; 2009 Jul 15; 8(14):1389-401. PubMed ID: 19483472
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  • 13. The relationship of erythropoietin overexpression with von Hippel-Lindau tumour suppressor gene mutations between hypoxia-inducible factor-1α and -2α in sporadic clear cell renal carcinoma.
    Gong K, Zhang N, Zhang K, Na Y.
    Int J Mol Med; 2010 Dec 15; 26(6):907-12. PubMed ID: 21042786
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  • 14. TGFBI-promoted adhesion, migration and invasion of human renal cell carcinoma depends on inactivation of von Hippel-Lindau tumor suppressor.
    Shang D, Liu Y, Yang P, Chen Y, Tian Y.
    Urology; 2012 Apr 15; 79(4):966.e1-7. PubMed ID: 22341602
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  • 17. Silencing of epidermal growth factor receptor suppresses hypoxia-inducible factor-2-driven VHL-/- renal cancer.
    Smith K, Gunaratnam L, Morley M, Franovic A, Mekhail K, Lee S.
    Cancer Res; 2005 Jun 15; 65(12):5221-30. PubMed ID: 15958567
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  • 19. Cisplatin-mediated c-myc overexpression and cytochrome c (cyt c) release result in the up-regulation of the death receptors DR4 and DR5 and the activation of caspase 3 and caspase 9, likely responsible for the TRAIL-sensitizing effect of cisplatin.
    Zhu X, Zhang K, Wang Q, Chen S, Gou Y, Cui Y, Li Q.
    Med Oncol; 2015 Apr 15; 32(4):133. PubMed ID: 25796504
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  • 20. Emetine promotes von Hippel-Lindau-independent degradation of hypoxia-inducible factor-2α in clear cell renal carcinoma.
    Kong HS, Lee S, Beebe K, Scroggins B, Gupta G, Lee MJ, Jung YJ, Trepel J, Neckers L.
    Mol Pharmacol; 2010 Dec 15; 78(6):1072-8. PubMed ID: 20813864
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