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450 related items for PubMed ID: 18546268

  • 1. Genistein selectively potentiates arsenic trioxide-induced apoptosis in human leukemia cells via reactive oxygen species generation and activation of reactive oxygen species-inducible protein kinases (p38-MAPK, AMPK).
    Sánchez Y, Amrán D, Fernández C, de Blas E, Aller P.
    Int J Cancer; 2008 Sep 01; 123(5):1205-14. PubMed ID: 18546268
    [Abstract] [Full Text] [Related]

  • 2. Modulation of arsenic trioxide-induced apoptosis by genistein and functionally related agents in U937 human leukaemia cells. Regulation by ROS and mitogen-activated protein kinases.
    Sánchez Y, Calle C, de Blas E, Aller P.
    Chem Biol Interact; 2009 Nov 10; 182(1):37-44. PubMed ID: 19720055
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  • 5. Quercetin decreases intracellular GSH content and potentiates the apoptotic action of the antileukemic drug arsenic trioxide in human leukemia cell lines.
    Ramos AM, Aller P.
    Biochem Pharmacol; 2008 May 15; 75(10):1912-23. PubMed ID: 18359480
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  • 6. Arsenic trioxide sensitizes promonocytic leukemia cells to TNFalpha-induced apoptosis via p38-MAPK-regulated activation of both receptor-mediated and mitochondrial pathways.
    Amrán D, Sánchez Y, Fernández C, Ramos AM, de Blas E, Bréard J, Calle C, Aller P.
    Biochim Biophys Acta; 2007 Nov 15; 1773(11):1653-63. PubMed ID: 17673311
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  • 7. 2-Deoxy-D-glucose cooperates with arsenic trioxide to induce apoptosis in leukemia cells: involvement of IGF-1R-regulated Akt/mTOR, MEK/ERK and LKB-1/AMPK signaling pathways.
    Estañ MC, Calviño E, de Blas E, Boyano-Adánez Mdel C, Mena ML, Gómez-Gómez M, Rial E, Aller P.
    Biochem Pharmacol; 2012 Dec 15; 84(12):1604-16. PubMed ID: 23041229
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  • 8. Potentiation of arsenic trioxide-induced apoptosis by 8-bromo-7-methoxychrysin in human leukemia cells involves depletion of intracellular reduced glutathione.
    Xiao G, Tang X, Yao C, Wang C.
    Acta Biochim Biophys Sin (Shanghai); 2011 Sep 15; 43(9):712-21. PubMed ID: 21785114
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  • 10. Pharmacologic inhibitors of extracellular signal-regulated kinase (ERKs) and c-Jun NH(2)-terminal kinase (JNK) decrease glutathione content and sensitize human promonocytic leukemia cells to arsenic trioxide-induced apoptosis.
    Ramos AM, Fernandez C, Amrán D, Esteban D, de Blas E, Palacios MA, Aller P.
    J Cell Physiol; 2006 Dec 15; 209(3):1006-15. PubMed ID: 16972261
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  • 11. ASK1 is activated by arsenic trioxide in leukemic cells through accumulation of reactive oxygen species and may play a negative role in induction of apoptosis.
    Yan W, Arai A, Aoki M, Ichijo H, Miura O.
    Biochem Biophys Res Commun; 2007 Apr 20; 355(4):1038-44. PubMed ID: 17331470
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  • 12. Arsenic trioxide and radiation enhance apoptotic effects in HL-60 cells through increased ROS generation and regulation of JNK and p38 MAPK signaling pathways.
    Ho SY, Wu WJ, Chiu HW, Chen YA, Ho YS, Guo HR, Wang YJ.
    Chem Biol Interact; 2011 Sep 05; 193(2):162-71. PubMed ID: 21741957
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  • 13. Metformin potentiates the effect of arsenic trioxide suppressing intrahepatic cholangiocarcinoma: roles of p38 MAPK, ERK3, and mTORC1.
    Ling S, Xie H, Yang F, Shan Q, Dai H, Zhuo J, Wei X, Song P, Zhou L, Xu X, Zheng S.
    J Hematol Oncol; 2017 Feb 28; 10(1):59. PubMed ID: 28241849
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  • 14. Coadministration of histone deacetylase inhibitors and perifosine synergistically induces apoptosis in human leukemia cells through Akt and ERK1/2 inactivation and the generation of ceramide and reactive oxygen species.
    Rahmani M, Reese E, Dai Y, Bauer C, Payne SG, Dent P, Spiegel S, Grant S.
    Cancer Res; 2005 Mar 15; 65(6):2422-32. PubMed ID: 15781658
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  • 15. Novel human neutrophil agonistic properties of arsenic trioxide: involvement of p38 mitogen-activated protein kinase and/or c-jun NH2-terminal MAPK but not extracellular signal-regulated kinases-1/2.
    Binet F, Girard D.
    J Leukoc Biol; 2008 Dec 15; 84(6):1613-22. PubMed ID: 18728151
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  • 16. The effect of MAPK inhibitors on arsenic trioxide-treated Calu-6 lung cells in relation to cell death, ROS and GSH levels.
    Han YH, Moon HJ, You BR, Kim SZ, Kim SH, Park WH.
    Anticancer Res; 2009 Oct 15; 29(10):3837-44. PubMed ID: 19846917
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  • 17. The synergistic antitumor activity of arsenic trioxide and vitamin K2 in HL-60 cells involves increased ROS generation and regulation of the ROS-dependent MAPK signaling pathway.
    Qu H, Tong D, Zhang Y, Kang K, Zhang Y, Chen L, Ren L.
    Pharmazie; 2013 Oct 15; 68(10):839-45. PubMed ID: 24273890
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  • 18. Pharmacologic inhibitors of PI3K/Akt potentiate the apoptotic action of the antileukemic drug arsenic trioxide via glutathione depletion and increased peroxide accumulation in myeloid leukemia cells.
    Ramos AM, Fernández C, Amrán D, Sancho P, de Blas E, Aller P.
    Blood; 2005 May 15; 105(10):4013-20. PubMed ID: 15665116
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  • 19. The role of p38 MAPK and JNK in Arsenic trioxide-induced mitochondrial cell death in human cervical cancer cells.
    Kang YH, Lee SJ.
    J Cell Physiol; 2008 Oct 15; 217(1):23-33. PubMed ID: 18412143
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  • 20. Regulation of genistein-induced differentiation in human acute myeloid leukaemia cells (HL60, NB4) Protein kinase modulation and reactive oxygen species generation.
    Sánchez Y, Amrán D, de Blas E, Aller P.
    Biochem Pharmacol; 2009 Feb 01; 77(3):384-96. PubMed ID: 19038232
    [Abstract] [Full Text] [Related]

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