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197 related items for PubMed ID: 18550547

  • 1. PKCdelta acts upstream of SPAK in the activation of NKCC1 by hyperosmotic stress in human airway epithelial cells.
    Smith L, Smallwood N, Altman A, Liedtke CM.
    J Biol Chem; 2008 Aug 08; 283(32):22147-56. PubMed ID: 18550547
    [Abstract] [Full Text] [Related]

  • 2. Role for protein phosphatase 2A in the regulation of Calu-3 epithelial Na+-K+-2Cl-, type 1 co-transport function.
    Liedtke CM, Wang X, Smallwood ND.
    J Biol Chem; 2005 Jul 08; 280(27):25491-8. PubMed ID: 15899883
    [Abstract] [Full Text] [Related]

  • 3. A single binding motif is required for SPAK activation of the Na-K-2Cl cotransporter.
    Gagnon KB, England R, Delpire E.
    Cell Physiol Biochem; 2007 Jul 08; 20(1-4):131-42. PubMed ID: 17595523
    [Abstract] [Full Text] [Related]

  • 4. Multiple pathways for protein phosphatase 1 (PP1) regulation of Na-K-2Cl cotransporter (NKCC1) function: the N-terminal tail of the Na-K-2Cl cotransporter serves as a regulatory scaffold for Ste20-related proline/alanine-rich kinase (SPAK) AND PP1.
    Gagnon KB, Delpire E.
    J Biol Chem; 2010 May 07; 285(19):14115-21. PubMed ID: 20223824
    [Abstract] [Full Text] [Related]

  • 5. Functional interactions of the SPAK/OSR1 kinases with their upstream activator WNK1 and downstream substrate NKCC1.
    Vitari AC, Thastrup J, Rafiqi FH, Deak M, Morrice NA, Karlsson HK, Alessi DR.
    Biochem J; 2006 Jul 01; 397(1):223-31. PubMed ID: 16669787
    [Abstract] [Full Text] [Related]

  • 6. Cation chloride cotransporters interact with the stress-related kinases Ste20-related proline-alanine-rich kinase (SPAK) and oxidative stress response 1 (OSR1).
    Piechotta K, Lu J, Delpire E.
    J Biol Chem; 2002 Dec 27; 277(52):50812-9. PubMed ID: 12386165
    [Abstract] [Full Text] [Related]

  • 7. Volume sensitivity of cation-Cl- cotransporters is modulated by the interaction of two kinases: Ste20-related proline-alanine-rich kinase and WNK4.
    Gagnon KB, England R, Delpire E.
    Am J Physiol Cell Physiol; 2006 Jan 27; 290(1):C134-42. PubMed ID: 15930150
    [Abstract] [Full Text] [Related]

  • 8. Stimulation of human and mouse erythrocyte Na(+)-K(+)-2Cl(-) cotransport by osmotic shrinkage does not involve AMP-activated protein kinase, but is associated with STE20/SPS1-related proline/alanine-rich kinase activation.
    Sid B, Miranda L, Vertommen D, Viollet B, Rider MH.
    J Physiol; 2010 Jul 01; 588(Pt 13):2315-28. PubMed ID: 20442269
    [Abstract] [Full Text] [Related]

  • 9. SPAK/OSR1 regulate NKCC1 and WNK activity: analysis of WNK isoform interactions and activation by T-loop trans-autophosphorylation.
    Thastrup JO, Rafiqi FH, Vitari AC, Pozo-Guisado E, Deak M, Mehellou Y, Alessi DR.
    Biochem J; 2012 Jan 01; 441(1):325-37. PubMed ID: 22032326
    [Abstract] [Full Text] [Related]

  • 10. On the substrate recognition and negative regulation of SPAK, a kinase modulating Na+-K+-2Cl- cotransport activity.
    Gagnon KB, Delpire E.
    Am J Physiol Cell Physiol; 2010 Sep 01; 299(3):C614-20. PubMed ID: 20463172
    [Abstract] [Full Text] [Related]

  • 11. Activation of NKCC1 by hyperosmotic stress in human tracheal epithelial cells involves PKC-delta and ERK.
    Liedtke CM, Cole TS.
    Biochim Biophys Acta; 2002 Feb 13; 1589(1):77-88. PubMed ID: 11909643
    [Abstract] [Full Text] [Related]

  • 12. A novel Ste20-related proline/alanine-rich kinase (SPAK)-independent pathway involving calcium-binding protein 39 (Cab39) and serine threonine kinase with no lysine member 4 (WNK4) in the activation of Na-K-Cl cotransporters.
    Ponce-Coria J, Markadieu N, Austin TM, Flammang L, Rios K, Welling PA, Delpire E.
    J Biol Chem; 2014 Jun 20; 289(25):17680-8. PubMed ID: 24811174
    [Abstract] [Full Text] [Related]

  • 13. Shrinkage insensitivity of NKCC1 in myosin II-depleted cytoplasts from Ehrlich ascites tumor cells.
    Hoffmann EK, Pedersen SF.
    Am J Physiol Cell Physiol; 2007 May 20; 292(5):C1854-66. PubMed ID: 17229812
    [Abstract] [Full Text] [Related]

  • 14. Characterization of the interaction of the stress kinase SPAK with the Na+-K+-2Cl- cotransporter in the nervous system: evidence for a scaffolding role of the kinase.
    Piechotta K, Garbarini N, England R, Delpire E.
    J Biol Chem; 2003 Dec 26; 278(52):52848-56. PubMed ID: 14563843
    [Abstract] [Full Text] [Related]

  • 15. COMMD1 interacts with the COOH terminus of NKCC1 in Calu-3 airway epithelial cells to modulate NKCC1 ubiquitination.
    Smith L, Litman P, Liedtke CM.
    Am J Physiol Cell Physiol; 2013 Jul 15; 305(2):C133-46. PubMed ID: 23515529
    [Abstract] [Full Text] [Related]

  • 16. The Ste20 kinases Ste20-related proline-alanine-rich kinase and oxidative-stress response 1 regulate NKCC1 function in sensory neurons.
    Geng Y, Hoke A, Delpire E.
    J Biol Chem; 2009 May 22; 284(21):14020-8. PubMed ID: 19307180
    [Abstract] [Full Text] [Related]

  • 17. Characterization of SPAK and OSR1, regulatory kinases of the Na-K-2Cl cotransporter.
    Gagnon KB, England R, Delpire E.
    Mol Cell Biol; 2006 Jan 22; 26(2):689-98. PubMed ID: 16382158
    [Abstract] [Full Text] [Related]

  • 18. Stability of actin cytoskeleton and PKC-delta binding to actin regulate NKCC1 function in airway epithelial cells.
    Liedtke CM, Hubbard M, Wang X.
    Am J Physiol Cell Physiol; 2003 Feb 22; 284(2):C487-96. PubMed ID: 12388079
    [Abstract] [Full Text] [Related]

  • 19. Apoptosis-associated tyrosine kinase scaffolding of protein phosphatase 1 and SPAK reveals a novel pathway for Na-K-2C1 cotransporter regulation.
    Gagnon KB, England R, Diehl L, Delpire E.
    Am J Physiol Cell Physiol; 2007 May 22; 292(5):C1809-15. PubMed ID: 17267545
    [Abstract] [Full Text] [Related]

  • 20. PASK (proline-alanine-rich STE20-related kinase), a regulatory kinase of the Na-K-Cl cotransporter (NKCC1).
    Dowd BF, Forbush B.
    J Biol Chem; 2003 Jul 25; 278(30):27347-53. PubMed ID: 12740379
    [Abstract] [Full Text] [Related]

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