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Journal Abstract Search

186 related items for PubMed ID: 18554908

  • 21.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 22. Design, synthesis and structure-activity relationship of simple bis-amides as potent inhibitors of GlyT1.
    Jolidon S, Alberati D, Dowle A, Fischer H, Hainzl D, Narquizian R, Norcross R, Pinard E.
    Bioorg Med Chem Lett; 2008 Oct 15; 18(20):5533-6. PubMed ID: 18805008
    [Abstract] [Full Text] [Related]

  • 23. Anthranilimide based glycogen phosphorylase inhibitors for the treatment of type 2 diabetes. Part 3: X-ray crystallographic characterization, core and urea optimization and in vivo efficacy.
    Thomson SA, Banker P, Bickett DM, Boucheron JA, Carter HL, Clancy DC, Cooper JP, Dickerson SH, Garrido DM, Nolte RT, Peat AJ, Sheckler LR, Sparks SM, Tavares FX, Wang L, Wang TY, Weiel JE.
    Bioorg Med Chem Lett; 2009 Feb 15; 19(4):1177-82. PubMed ID: 19138846
    [Abstract] [Full Text] [Related]

  • 24. Synthesis and evaluation of 3-anilino-quinoxalinones as glycogen phosphorylase inhibitors.
    Dudash J, Zhang Y, Moore JB, Look R, Liang Y, Beavers MP, Conway BR, Rybczynski PJ, Demarest KT.
    Bioorg Med Chem Lett; 2005 Nov 01; 15(21):4790-3. PubMed ID: 16143521
    [Abstract] [Full Text] [Related]

  • 25. Rapid assessment of a novel series of selective CB(2) agonists using parallel synthesis protocols: A Lipophilic Efficiency (LipE) analysis.
    Ryckmans T, Edwards MP, Horne VA, Correia AM, Owen DR, Thompson LR, Tran I, Tutt MF, Young T.
    Bioorg Med Chem Lett; 2009 Aug 01; 19(15):4406-9. PubMed ID: 19500981
    [Abstract] [Full Text] [Related]

  • 26. 1,4-Dihydroindeno[1,2-c]pyrazoles as novel multitargeted receptor tyrosine kinase inhibitors.
    Dinges J, Ashworth KL, Akritopoulou-Zanze I, Arnold LD, Baumeister SA, Bousquet PF, Cunha GA, Davidsen SK, Djuric SW, Gracias VJ, Michaelides MR, Rafferty P, Sowin TJ, Stewart KD, Xia Z, Zhang HQ.
    Bioorg Med Chem Lett; 2006 Aug 15; 16(16):4266-71. PubMed ID: 16759855
    [Abstract] [Full Text] [Related]

  • 27. Identification of substituted pyrazolo[1,5-a]quinazolin-5(4H)-one as potent poly(ADP-ribose)polymerase-1 (PARP-1) inhibitors.
    Orvieto F, Branca D, Giomini C, Jones P, Koch U, Ontoria JM, Palumbi MC, Rowley M, Toniatti C, Muraglia E.
    Bioorg Med Chem Lett; 2009 Aug 01; 19(15):4196-200. PubMed ID: 19541484
    [Abstract] [Full Text] [Related]

  • 28. Discovery of 6-ethyl-2,4-diaminopyrimidine-based small molecule renin inhibitors.
    Holsworth DD, Jalaie M, Belliotti T, Cai C, Collard W, Ferreira S, Powell NA, Stier M, Zhang E, McConnell P, Mochalkin I, Ryan MJ, Bryant J, Li T, Kasani A, Subedi R, Maiti SN, Edmunds JJ.
    Bioorg Med Chem Lett; 2007 Jul 01; 17(13):3575-80. PubMed ID: 17482464
    [Abstract] [Full Text] [Related]

  • 29. Discovery of pyrimidine benzimidazoles as Lck inhibitors: part I.
    Zhang G, Ren P, Gray NS, Sim T, Liu Y, Wang X, Che J, Tian SS, Sandberg ML, Spalding TA, Romeo R, Iskandar M, Chow D, Martin Seidel H, Karanewsky DS, He Y.
    Bioorg Med Chem Lett; 2008 Oct 15; 18(20):5618-21. PubMed ID: 18793846
    [Abstract] [Full Text] [Related]

  • 30. Design, synthesis, and SAR of anthranilamide-based factor Xa inhibitors with improved functional activity.
    Zhang P, Bao L, Zuckett JF, Jia ZJ, Woolfrey J, Arfsten A, Edwards S, Sinha U, Hutchaleelaha A, Lambing JL, Hollenbach SJ, Scarborough RM, Zhu BY.
    Bioorg Med Chem Lett; 2004 Feb 23; 14(4):989-93. PubMed ID: 15013007
    [Abstract] [Full Text] [Related]

  • 31. Design, synthesis, biological evaluation, and structure-activity relationship (SAR) discussion of dipeptidyl boronate proteasome inhibitors, part I: comprehensive understanding of the SAR of alpha-amino acid boronates.
    Zhu Y, Zhao X, Zhu X, Wu G, Li Y, Ma Y, Yuan Y, Yang J, Hu Y, Ai L, Gao Q.
    J Med Chem; 2009 Jul 23; 52(14):4192-9. PubMed ID: 19537716
    [Abstract] [Full Text] [Related]

  • 32. Discovery of a potent, selective, and less flexible selective norepinephrine reuptake inhibitor (sNRI).
    Wu D, Pontillo J, Ching B, Hudson S, Gao Y, Fleck BA, Gogas K, Wade WS.
    Bioorg Med Chem Lett; 2008 Jul 15; 18(14):4224-7. PubMed ID: 18550369
    [Abstract] [Full Text] [Related]

  • 33. Small, non-peptide C5a receptor antagonists: part 1.
    Blagg J, Mowbray C, Pryde DC, Salmon G, Schmid E, Fairman D, Beaumont K.
    Bioorg Med Chem Lett; 2008 Oct 15; 18(20):5601-4. PubMed ID: 18809326
    [Abstract] [Full Text] [Related]

  • 34. Discovery of dihydroquinoxalinone acetamides containing bicyclic amines as potent Bradykinin B1 receptor antagonists.
    Chen JJ, Qian W, Biswas K, Viswanadhan VN, Askew BC, Hitchcock S, Hungate RW, Arik L, Johnson E.
    Bioorg Med Chem Lett; 2008 Aug 15; 18(16):4477-81. PubMed ID: 18674903
    [Abstract] [Full Text] [Related]

  • 35. Synthesis and structure-activity relationships of 2-amino-1-aroylnaphthalene and 2-hydroxy-1-aroylnaphthalenes as potent antitubulin agents.
    Reddy GR, Kuo CC, Tan UK, Coumar MS, Chang CY, Chiang YK, Lai MJ, Yeh JY, Wu SY, Chang JY, Liou JP, Hsieh HP.
    J Med Chem; 2008 Dec 25; 51(24):8163-7. PubMed ID: 19053773
    [Abstract] [Full Text] [Related]

  • 36. Matched molecular pair analysis of activity and properties of glycogen phosphorylase inhibitors.
    Birch AM, Kenny PW, Simpson I, Whittamore PR.
    Bioorg Med Chem Lett; 2009 Feb 01; 19(3):850-3. PubMed ID: 19103484
    [Abstract] [Full Text] [Related]

  • 37. The identification and optimisation of novel and selective diamide neuropeptide Y Y2 receptor antagonists.
    Lunniss GE, Barnes AA, Barton N, Biagetti M, Bianchi F, Blowers SM, Caberlotto L, Emmons A, Holmes IP, Montanari D, Norris R, Walters DJ, Watson SP.
    Bioorg Med Chem Lett; 2009 Aug 01; 19(15):4022-5. PubMed ID: 19581086
    [Abstract] [Full Text] [Related]

  • 38. 4-Amino-6-arylamino-pyrimidine-5-carbaldehyde hydrazones as potent ErbB-2/EGFR dual kinase inhibitors.
    Xu G, Abad MC, Connolly PJ, Neeper MP, Struble GT, Springer BA, Emanuel SL, Pandey N, Gruninger RH, Adams M, Moreno-Mazza S, Fuentes-Pesquera AR, Middleton SA.
    Bioorg Med Chem Lett; 2008 Aug 15; 18(16):4615-9. PubMed ID: 18653333
    [Abstract] [Full Text] [Related]

  • 39. 4-Amino-6-piperazin-1-yl-pyrimidine-5-carbaldehyde oximes as potent FLT-3 inhibitors.
    Gaul MD, Xu G, Kirkpatrick J, Ott H, Baumann CA.
    Bioorg Med Chem Lett; 2007 Sep 01; 17(17):4861-5. PubMed ID: 17611106
    [Abstract] [Full Text] [Related]

  • 40. 4-Phenyl-7-azaindoles as potent and selective IKK2 inhibitors.
    Liddle J, Bamborough P, Barker MD, Campos S, Cousins RP, Cutler GJ, Hobbs H, Holmes DS, Ioannou C, Mellor GW, Morse MA, Payne JJ, Pritchard JM, Smith KJ, Tape DT, Whitworth C, Williamson RA.
    Bioorg Med Chem Lett; 2009 May 01; 19(9):2504-8. PubMed ID: 19349179
    [Abstract] [Full Text] [Related]

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