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282 related items for PubMed ID: 18557699

  • 1. Abnormal expression of only the CD34 part of a transgenic CD34/herpes simplex virus-thymidine kinase fusion protein is associated with ganciclovir resistance.
    Bennour E, Ferrand C, Rémy-Martin JP, Certoux JM, Gorke S, Qasim W, Gaspar HB, Baumert T, Duperrier A, Deschamps M, Fehse B, Tiberghien P, Robinet E.
    Hum Gene Ther; 2008 Jul; 19(7):699-709. PubMed ID: 18557699
    [Abstract] [Full Text] [Related]

  • 2. Molecular mechanism for ganciclovir resistance in human T lymphocytes transduced with retroviral vectors carrying the herpes simplex virus thymidine kinase gene.
    Garin MI, Garrett E, Tiberghien P, Apperley JF, Chalmers D, Melo JV, Ferrand C.
    Blood; 2001 Jan 01; 97(1):122-9. PubMed ID: 11133751
    [Abstract] [Full Text] [Related]

  • 3. Mechanisms for ganciclovir resistance in gastrointestinal tumor cells transduced with a retroviral vector containing the herpes simplex virus thymidine kinase gene.
    Yang L, Hwang R, Chiang Y, Gordon EM, Anderson WF, Parekh D.
    Clin Cancer Res; 1998 Mar 01; 4(3):731-41. PubMed ID: 9533543
    [Abstract] [Full Text] [Related]

  • 4. Elimination of the truncated message from the herpes simplex virus thymidine kinase suicide gene.
    Chalmers D, Ferrand C, Apperley JF, Melo JV, Ebeling S, Newton I, Duperrier A, Hagenbeek A, Garrett E, Tiberghien P, Garin M.
    Mol Ther; 2001 Aug 01; 4(2):146-8. PubMed ID: 11482986
    [Abstract] [Full Text] [Related]

  • 5. TK-GFP fusion gene virus vectors as tools for studying the features of HSV-TK/ganciclovir cancer gene therapy in vivo.
    Pasanen T, Hakkarainen T, Timonen P, Parkkinen J, Tenhunen A, Loimas S, Wahlfors J.
    Int J Mol Med; 2003 Oct 01; 12(4):525-31. PubMed ID: 12964030
    [Abstract] [Full Text] [Related]

  • 6. BCR-ABL-expressing cells transduced with the HSV-tk gene die by apoptosis upon treatment with ganciclovir.
    Rivas C, Miller AR, Collado M, Lam EW, Apperley JF, Melo JV.
    Mol Ther; 2001 May 01; 3(5 Pt 1):642-52. PubMed ID: 11356068
    [Abstract] [Full Text] [Related]

  • 7. VP22 enhanced intercellular trafficking of HSV thymidine kinase reduced the level of ganciclovir needed to cause suicide cell death.
    Liu CS, Kong B, Xia HH, Ellem KA, Wei MQ.
    J Gene Med; 2001 May 01; 3(2):145-52. PubMed ID: 11318113
    [Abstract] [Full Text] [Related]

  • 8. VP22 does not significantly enhance enzyme prodrug cancer gene therapy as a part of a VP22-HSVTk-GFP triple fusion construct.
    Hakkarainen T, Wahlfors T, Meriläinen O, Loimas S, Hemminki A, Wahlfors J.
    J Gene Med; 2005 Jul 01; 7(7):898-907. PubMed ID: 15759279
    [Abstract] [Full Text] [Related]

  • 9. Retrovirus-mediated gene therapy of experimental brain neoplasms using the herpes simplex virus-thymidine kinase/ganciclovir paradigm.
    Rainov NG, Kramm CM, Aboody-Guterman K, Chase M, Ueki K, Louis DN, Harsh GR, Chiocca A, Breakefield XO.
    Cancer Gene Ther; 1996 Jul 01; 3(2):99-106. PubMed ID: 8729908
    [Abstract] [Full Text] [Related]

  • 10. In situ generation of pseudotyped retroviral progeny by adenovirus-mediated transduction of tumor cells enhances the killing effect of HSV-tk suicide gene therapy in vitro and in vivo.
    Okada T, Caplen NJ, Ramsey WJ, Onodera M, Shimazaki K, Nomoto T, Ajalli R, Wildner O, Morris J, Kume A, Hamada H, Blaese RM, Ozawa K.
    J Gene Med; 2004 Mar 01; 6(3):288-99. PubMed ID: 15026990
    [Abstract] [Full Text] [Related]

  • 11. Experimental study of the RV-HSV-TK/GCV suicide gene therapy system in gastric cancer.
    Tang Q, Zhang D, Wan M, Jin L.
    Cancer Biother Radiopharm; 2007 Dec 01; 22(6):755-61. PubMed ID: 18158766
    [Abstract] [Full Text] [Related]

  • 12. [Bystander effect mediated by herpes simplex virus-thymidine kinase/ganciclovir approach on prostatic cancer cells and its regulation].
    Xing Y, Lu G, Xiao Y, Zeng F, Zhang Q, Xiong P, Feng W.
    Zhonghua Yi Xue Za Zhi; 2002 Nov 10; 82(21):1484-7. PubMed ID: 12509912
    [Abstract] [Full Text] [Related]

  • 13. Transduction of human pancreatic tumor cells with vesicular stomatitis virus G-pseudotyped retroviral vectors containing a herpes simplex virus thymidine kinase mutant gene enhances bystander effects and sensitivity to ganciclovir.
    Howard BD, Boenicke L, Schniewind B, Henne-Bruns D, Kalthoff H.
    Cancer Gene Ther; 2000 Jun 10; 7(6):927-38. PubMed ID: 10880025
    [Abstract] [Full Text] [Related]

  • 14. [Experimental studies on the characteristics of suicide gene system HSV-tk/GCV and its effect on dendritic cells].
    Wang X, Li L, Feng K, Bai L, Pei X.
    Zhonghua Xue Ye Xue Za Zhi; 2000 Dec 10; 21(12):628-31. PubMed ID: 11877036
    [Abstract] [Full Text] [Related]

  • 15. Enhanced ganciclovir killing and bystander effect of human tumor cells transduced with a retroviral vector carrying a herpes simplex virus thymidine kinase gene mutant.
    Qiao J, Black ME, Caruso M.
    Hum Gene Ther; 2000 Jul 20; 11(11):1569-76. PubMed ID: 10945770
    [Abstract] [Full Text] [Related]

  • 16. Characteristics of ovarian cancer cells transduced by the bicistronic retroviral vector containing GM-CSF and HSV-TK genes.
    Guan J, Ma L, Wei L.
    Chin Med J (Engl); 2001 Feb 20; 114(2):147-51. PubMed ID: 11780195
    [Abstract] [Full Text] [Related]

  • 17. Retrovector encoding a green fluorescent protein-herpes simplex virus thymidine kinase fusion protein serves as a versatile suicide/reporter for cell and gene therapy applications.
    Paquin A, Jaalouk DE, Galipeau J.
    Hum Gene Ther; 2001 Jan 01; 12(1):13-23. PubMed ID: 11177538
    [Abstract] [Full Text] [Related]

  • 18. [Hypoxia responsive element regulated herpes simplex virus-thymidine kinase system enhances killing effect of gancyclovir on Ewing's sarcoma cell line under hypoxic condition].
    Si YJ, Guang LX, Yuan FH, Zhang KB.
    Zhonghua Er Ke Za Zhi; 2006 Aug 01; 44(8):616-20. PubMed ID: 17083794
    [Abstract] [Full Text] [Related]

  • 19. Herpes simplex virus thymidine kinase gene transduction enhances tumor growth rate and cyclooxygenase-2 expression in murine colon cancer cells.
    Konson A, Ben-Kasus T, Mahajna JA, Danon A, Rimon G, Agbaria R.
    Cancer Gene Ther; 2004 Dec 01; 11(12):830-40. PubMed ID: 15359292
    [Abstract] [Full Text] [Related]

  • 20. DNA-liposome complexes transduction of herpes simplex virus thymidine kinase renders human tongue cancer cell line sensitive to ganciclovir in vitro.
    Wang JH, Situ ZQ, Wu JZ, Liu B.
    Chin J Dent Res; 2000 Dec 01; 3(4):44-8. PubMed ID: 11314087
    [Abstract] [Full Text] [Related]

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