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446 related items for PubMed ID: 18563359

  • 1. In vitro characterization of the enzymes involved in the metabolism of 1-furan-2-yl-3-pyridin-2-yl-propenone, an anti-inflammatory propenone compound.
    Lee SK, Kim JH, Seo YM, Kim HC, Kang MJ, Jeong HG, Lee ES, Jeong TC.
    Arch Pharm Res; 2008 Jun; 31(6):764-70. PubMed ID: 18563359
    [Abstract] [Full Text] [Related]

  • 2. Determination of 1-furan-2-yl-3-pyridin-2-yl-propenone, an anti-inflammatory propenone compound, by high performance liquid chromatography with ultraviolet spectrometry.
    Lee SK, Jeon TW, Basnet A, Lee ES, Jeong TC.
    J Chromatogr B Analyt Technol Biomed Life Sci; 2006 Jun 06; 837(1-2):108-11. PubMed ID: 16687255
    [Abstract] [Full Text] [Related]

  • 3. Identification of 1-furan-2-yl-3-pyridin-2-yl-propenone, an antiinflammatory agent, and its metabolites in rat liver subcellular fractions.
    Lee SK, Jeon TW, Basnet A, Jeong HG, Lee ES, Jeong TC.
    Arch Pharm Res; 2006 Nov 06; 29(11):984-9. PubMed ID: 17146967
    [Abstract] [Full Text] [Related]

  • 4. Metabolism of FPP-3, an anti-inflammatory propenone compound, in rat by liquid chromatography-electrospray ionization tandem mass spectrometry.
    Lee SK, Jeong HG, Lee ES, Jeong TC.
    Biol Pharm Bull; 2007 May 06; 30(5):967-71. PubMed ID: 17473444
    [Abstract] [Full Text] [Related]

  • 5. Effects of glycyrrhetinic acid derivatives on hepatic and renal 11beta-hydroxysteroid dehydrogenase activities in rats.
    Shimoyama Y, Hirabayashi K, Matsumoto H, Sato T, Shibata S, Inoue H.
    J Pharm Pharmacol; 2003 Jun 06; 55(6):811-7. PubMed ID: 12841942
    [Abstract] [Full Text] [Related]

  • 6. The anti-angiogenic effects of 1-furan-2-yl-3-pyridin-2-yl-propenone are mediated through the suppression of both VEGF production and VEGF-induced signaling.
    Park BC, Park SY, Lee JS, Mousa SA, Kim JT, Kwak MK, Kang KW, Lee ES, Choi HG, Yong CS, Kim JA.
    Vascul Pharmacol; 2009 Jun 06; 50(3-4):123-31. PubMed ID: 19068239
    [Abstract] [Full Text] [Related]

  • 7. Carbonyl reduction of bupropion in human liver.
    Molnari JC, Myers AL.
    Xenobiotica; 2012 Jun 06; 42(6):550-61. PubMed ID: 22339467
    [Abstract] [Full Text] [Related]

  • 8. Chemopreventive effects of Furan-2-yl-3-pyridin-2-yl-propenone against 7,12-dimethylbenz[a]anthracene-inducible genotoxicity.
    Hwang YP, Han EH, Choi JH, Kim HG, Lee KJ, Jeong TC, Lee ES, Jeong HG.
    Toxicol Appl Pharmacol; 2008 May 01; 228(3):343-50. PubMed ID: 18255114
    [Abstract] [Full Text] [Related]

  • 9. Enantioselectivity of carbonyl reduction of 4-methylnitrosamino-1-(3-pyridyl)-1-butanone by tissue fractions from human and rat and by enzymes isolated from human liver.
    Breyer-Pfaff U, Martin HJ, Ernst M, Maser E.
    Drug Metab Dispos; 2004 Sep 01; 32(9):915-22. PubMed ID: 15319331
    [Abstract] [Full Text] [Related]

  • 10. Biotransformation and detoxification of insecticidal metyrapone analogues by carbonyl reduction in the human liver.
    Rekka EA, Soldan M, Belai I, Netter KJ, Maser E.
    Xenobiotica; 1996 Dec 01; 26(12):1221-9. PubMed ID: 9004452
    [Abstract] [Full Text] [Related]

  • 11. 1-furan-2-yl-3-pyridin-2-yl-propenone inhibits the invasion and migration of HT1080 human fibrosarcoma cells through the inhibition of proMMP-2 activation and down regulation of MMP-9 and MT1-MMP.
    Park BC, Thapa D, Lee YS, Kwak MK, Lee ES, Choi HG, Yong CS, Kim JA.
    Eur J Pharmacol; 2007 Jul 19; 567(3):193-7. PubMed ID: 17507007
    [Abstract] [Full Text] [Related]

  • 12. Reductive metabolism of nabumetone by human liver microsomal and cytosolic fractions: exploratory prediction using inhibitors and substrates as marker probes.
    Matsumoto K, Hasegawa T, Koyanagi J, Takahashi T, Akimoto M, Sugibayashi K.
    Eur J Drug Metab Pharmacokinet; 2015 Jun 19; 40(2):127-35. PubMed ID: 24659525
    [Abstract] [Full Text] [Related]

  • 13. Partial purification and characterization of a new human membrane-bound carbonyl reductase playing a role in the deactivation of the anticancer drug oracin.
    Skarydová L, Skarka A, Novotná R, Zivná L, Martin HJ, Wsól V, Maser E.
    Toxicology; 2009 Oct 01; 264(1-2):52-60. PubMed ID: 19635524
    [Abstract] [Full Text] [Related]

  • 14. Enzymology of a carbonyl reduction clearance pathway for the HIV integrase inhibitor, S-1360: role of human liver cytosolic aldo-keto reductases.
    Rosemond MJ, St John-Williams L, Yamaguchi T, Fujishita T, Walsh JS.
    Chem Biol Interact; 2004 Mar 15; 147(2):129-39. PubMed ID: 15013815
    [Abstract] [Full Text] [Related]

  • 15. Potent analgesic and anti-inflammatory activities of 1-furan-2-yl-3-pyridin-2-yl-propenone with gastric ulcer sparing effect.
    Lee ES, Park BC, Paek SH, Lee YS, Basnet A, Jin DQ, Choi HG, Yong CS, Kim JA.
    Biol Pharm Bull; 2006 Feb 15; 29(2):361-4. PubMed ID: 16462046
    [Abstract] [Full Text] [Related]

  • 16. Activation of the Nrf2-antioxidant system by a novel cyclooxygenase-2 inhibitor furan-2-yl-3-pyridin-2-yl-propenone: implication in anti-inflammatory function by Nrf2 activator.
    Manandhar S, You A, Lee ES, Kim JA, Kwak MK.
    J Pharm Pharmacol; 2008 Jul 15; 60(7):879-87. PubMed ID: 18549674
    [Abstract] [Full Text] [Related]

  • 17. Hepatic and extra-hepatic metabolic pathways involved in flubendazole biotransformation in sheep.
    Maté L, Virkel G, Lifschitz A, Ballent M, Lanusse C.
    Biochem Pharmacol; 2008 Sep 15; 76(6):773-83. PubMed ID: 18671949
    [Abstract] [Full Text] [Related]

  • 18. Chiral inversion of RS-8359: a selective and reversible MAO-A inhibitor via oxido-reduction of keto-alcohol.
    Itoh K, Hoshino K, Endo A, Asakawa T, Yamakami K, Noji C, Kosaka T, Tanaka Y.
    Chirality; 2006 Sep 15; 18(9):698-706. PubMed ID: 16823812
    [Abstract] [Full Text] [Related]

  • 19. Reductive metabolism of the sanguinarine iminium bond by rat liver preparations.
    Wu Y, Liu ZY, Cao Y, Chen XJ, Zeng JG, Sun ZL.
    Pharmacol Rep; 2013 Sep 15; 65(5):1391-400. PubMed ID: 24399736
    [Abstract] [Full Text] [Related]

  • 20. Anthracyclines and their metabolism in human liver microsomes and the participation of the new microsomal carbonyl reductase.
    Skarka A, Skarydová L, Stambergová H, Wsól V.
    Chem Biol Interact; 2011 May 30; 191(1-3):66-74. PubMed ID: 21185270
    [Abstract] [Full Text] [Related]

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