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Journal Abstract Search

637 related items for PubMed ID: 18566231

  • 1. Pinitol targets nuclear factor-kappaB activation pathway leading to inhibition of gene products associated with proliferation, apoptosis, invasion, and angiogenesis.
    Sethi G, Ahn KS, Sung B, Aggarwal BB.
    Mol Cancer Ther; 2008 Jun; 7(6):1604-14. PubMed ID: 18566231
    [Abstract] [Full Text] [Related]

  • 2. Coronarin D, a labdane diterpene, inhibits both constitutive and inducible nuclear factor-kappa B pathway activation, leading to potentiation of apoptosis, inhibition of invasion, and suppression of osteoclastogenesis.
    Kunnumakkara AB, Ichikawa H, Anand P, Mohankumar CJ, Hema PS, Nair MS, Aggarwal BB.
    Mol Cancer Ther; 2008 Oct; 7(10):3306-17. PubMed ID: 18852134
    [Abstract] [Full Text] [Related]

  • 3. Fisetin, an inhibitor of cyclin-dependent kinase 6, down-regulates nuclear factor-kappaB-regulated cell proliferation, antiapoptotic and metastatic gene products through the suppression of TAK-1 and receptor-interacting protein-regulated IkappaBalpha kinase activation.
    Sung B, Pandey MK, Aggarwal BB.
    Mol Pharmacol; 2007 Jun; 71(6):1703-14. PubMed ID: 17387141
    [Abstract] [Full Text] [Related]

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  • 7. N-(4-hydroxyphenyl)retinamide inhibits invasion, suppresses osteoclastogenesis, and potentiates apoptosis through down-regulation of I(kappa)B(alpha) kinase and nuclear factor-kappaB-regulated gene products.
    Shishodia S, Gutierrez AM, Lotan R, Aggarwal BB.
    Cancer Res; 2005 Oct 15; 65(20):9555-65. PubMed ID: 16230421
    [Abstract] [Full Text] [Related]

  • 8. 3-Formylchromone interacts with cysteine 38 in p65 protein and with cysteine 179 in IκBα kinase, leading to down-regulation of nuclear factor-κB (NF-κB)-regulated gene products and sensitization of tumor cells.
    Yadav VR, Prasad S, Gupta SC, Sung B, Phatak SS, Zhang S, Aggarwal BB.
    J Biol Chem; 2012 Jan 02; 287(1):245-256. PubMed ID: 22065587
    [Abstract] [Full Text] [Related]

  • 9. Cryptopleurine targets NF-κB pathway, leading to inhibition of gene products associated with cell survival, proliferation, invasion, and angiogenesis.
    Jin HR, Jin SZ, Cai XF, Li D, Wu X, Nan JX, Lee JJ, Jin X.
    PLoS One; 2012 Jan 02; 7(6):e40355. PubMed ID: 22768286
    [Abstract] [Full Text] [Related]

  • 10. Celastrol, a novel triterpene, potentiates TNF-induced apoptosis and suppresses invasion of tumor cells by inhibiting NF-kappaB-regulated gene products and TAK1-mediated NF-kappaB activation.
    Sethi G, Ahn KS, Pandey MK, Aggarwal BB.
    Blood; 2007 Apr 01; 109(7):2727-35. PubMed ID: 17110449
    [Abstract] [Full Text] [Related]

  • 11. Morin (3,5,7,2',4'-Pentahydroxyflavone) abolishes nuclear factor-kappaB activation induced by various carcinogens and inflammatory stimuli, leading to suppression of nuclear factor-kappaB-regulated gene expression and up-regulation of apoptosis.
    Manna SK, Aggarwal RS, Sethi G, Aggarwal BB, Ramesh GT.
    Clin Cancer Res; 2007 Apr 01; 13(7):2290-7. PubMed ID: 17404114
    [Abstract] [Full Text] [Related]

  • 12. Suppression of constitutive and tumor necrosis factor alpha-induced nuclear factor (NF)-kappaB activation and induction of apoptosis by apigenin in human prostate carcinoma PC-3 cells: correlation with down-regulation of NF-kappaB-responsive genes.
    Shukla S, Gupta S.
    Clin Cancer Res; 2004 May 01; 10(9):3169-78. PubMed ID: 15131058
    [Abstract] [Full Text] [Related]

  • 13. Curcumin (diferuloylmethane) down-regulates expression of cell proliferation and antiapoptotic and metastatic gene products through suppression of IkappaBalpha kinase and Akt activation.
    Aggarwal S, Ichikawa H, Takada Y, Sandur SK, Shishodia S, Aggarwal BB.
    Mol Pharmacol; 2006 Jan 01; 69(1):195-206. PubMed ID: 16219905
    [Abstract] [Full Text] [Related]

  • 14. Gossypin, a pentahydroxy glucosyl flavone, inhibits the transforming growth factor beta-activated kinase-1-mediated NF-kappaB activation pathway, leading to potentiation of apoptosis, suppression of invasion, and abrogation of osteoclastogenesis.
    Kunnumakkara AB, Nair AS, Ahn KS, Pandey MK, Yi Z, Liu M, Aggarwal BB.
    Blood; 2007 Jun 15; 109(12):5112-21. PubMed ID: 17332240
    [Abstract] [Full Text] [Related]

  • 15. Evodiamine abolishes constitutive and inducible NF-kappaB activation by inhibiting IkappaBalpha kinase activation, thereby suppressing NF-kappaB-regulated antiapoptotic and metastatic gene expression, up-regulating apoptosis, and inhibiting invasion.
    Takada Y, Kobayashi Y, Aggarwal BB.
    J Biol Chem; 2005 Apr 29; 280(17):17203-12. PubMed ID: 15710601
    [Abstract] [Full Text] [Related]

  • 16. Plumbagin (5-hydroxy-2-methyl-1,4-naphthoquinone) suppresses NF-kappaB activation and NF-kappaB-regulated gene products through modulation of p65 and IkappaBalpha kinase activation, leading to potentiation of apoptosis induced by cytokine and chemotherapeutic agents.
    Sandur SK, Ichikawa H, Sethi G, Ahn KS, Aggarwal BB.
    J Biol Chem; 2006 Jun 23; 281(25):17023-17033. PubMed ID: 16624823
    [Abstract] [Full Text] [Related]

  • 17. Cyclooxygenase (COX)-2 inhibitor celecoxib abrogates TNF-induced NF-kappa B activation through inhibition of activation of I kappa B alpha kinase and Akt in human non-small cell lung carcinoma: correlation with suppression of COX-2 synthesis.
    Shishodia S, Koul D, Aggarwal BB.
    J Immunol; 2004 Aug 01; 173(3):2011-22. PubMed ID: 15265936
    [Abstract] [Full Text] [Related]

  • 18. Targeting nuclear factor-kappa B activation pathway by thymoquinone: role in suppression of antiapoptotic gene products and enhancement of apoptosis.
    Sethi G, Ahn KS, Aggarwal BB.
    Mol Cancer Res; 2008 Jun 01; 6(6):1059-70. PubMed ID: 18567808
    [Abstract] [Full Text] [Related]

  • 19. Identification of a p65 peptide that selectively inhibits NF-kappa B activation induced by various inflammatory stimuli and its role in down-regulation of NF-kappaB-mediated gene expression and up-regulation of apoptosis.
    Takada Y, Singh S, Aggarwal BB.
    J Biol Chem; 2004 Apr 09; 279(15):15096-104. PubMed ID: 14711835
    [Abstract] [Full Text] [Related]

  • 20. Indole-3-carbinol suppresses NF-kappaB and IkappaBalpha kinase activation, causing inhibition of expression of NF-kappaB-regulated antiapoptotic and metastatic gene products and enhancement of apoptosis in myeloid and leukemia cells.
    Takada Y, Andreeff M, Aggarwal BB.
    Blood; 2005 Jul 15; 106(2):641-9. PubMed ID: 15811958
    [Abstract] [Full Text] [Related]

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