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Journal Abstract Search

182 related items for PubMed ID: 1857342

  • 1. Separation of human liver microsomal tolbutamide hydroxylase and (S)-mephenytoin 4'-hydroxylase cytochrome P-450 enzymes.
    Srivastava PK, Yun CH, Beaune PH, Ged C, Guengerich FP.
    Mol Pharmacol; 1991 Jul; 40(1):69-79. PubMed ID: 1857342
    [Abstract] [Full Text] [Related]

  • 2. Characterization of CYP2C19 and CYP2C9 from human liver: respective roles in microsomal tolbutamide, S-mephenytoin, and omeprazole hydroxylations.
    Lasker JM, Wester MR, Aramsombatdee E, Raucy JL.
    Arch Biochem Biophys; 1998 May 01; 353(1):16-28. PubMed ID: 9578596
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  • 3. Human liver microsomal cytochrome P-450 mephenytoin 4-hydroxylase, a prototype of genetic polymorphism in oxidative drug metabolism. Purification and characterization of two similar forms involved in the reaction.
    Shimada T, Misono KS, Guengerich FP.
    J Biol Chem; 1986 Jan 15; 261(2):909-21. PubMed ID: 3079764
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  • 4. Evidence that CYP2C19 is the major (S)-mephenytoin 4'-hydroxylase in humans.
    Goldstein JA, Faletto MB, Romkes-Sparks M, Sullivan T, Kitareewan S, Raucy JL, Lasker JM, Ghanayem BI.
    Biochemistry; 1994 Feb 22; 33(7):1743-52. PubMed ID: 8110777
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  • 5. Site-directed mutation studies of human liver cytochrome P-450 isoenzymes in the CYP2C subfamily.
    Veronese ME, Doecke CJ, Mackenzie PI, McManus ME, Miners JO, Rees DL, Gasser R, Meyer UA, Birkett DJ.
    Biochem J; 1993 Jan 15; 289 ( Pt 2)(Pt 2):533-8. PubMed ID: 8424795
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  • 6. Characterization of monkey cytochrome P450, P450 CMLd, responsible for S-mephenytoin 4-hydroxylation in hepatic microsomes of cynomolgus monkeys.
    Ohmori S, Chiba K, Nakasa H, Horie T, Kitada M.
    Arch Biochem Biophys; 1994 Jun 15; 311(2):395-401. PubMed ID: 8203903
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  • 7. Characterization of cDNAs, mRNAs, and proteins related to human liver microsomal cytochrome P-450 (S)-mephenytoin 4'-hydroxylase.
    Ged C, Umbenhauer DR, Bellew TM, Bork RW, Srivastava PK, Shinriki N, Lloyd RS, Guengerich FP.
    Biochemistry; 1988 Sep 06; 27(18):6929-40. PubMed ID: 3196692
    [Abstract] [Full Text] [Related]

  • 8. CYP2C19 participates in tolbutamide hydroxylation by human liver microsomes.
    Wester MR, Lasker JM, Johnson EF, Raucy JL.
    Drug Metab Dispos; 2000 Mar 06; 28(3):354-9. PubMed ID: 10681382
    [Abstract] [Full Text] [Related]

  • 9. Expression of a human liver cytochrome P-450 protein with tolbutamide hydroxylase activity in Saccharomyces cerevisiae.
    Brian WR, Srivastava PK, Umbenhauer DR, Lloyd RS, Guengerich FP.
    Biochemistry; 1989 Jun 13; 28(12):4993-9. PubMed ID: 2669966
    [Abstract] [Full Text] [Related]

  • 10. Relationship between CYP2C9 and 2C19 genotypes and tolbutamide methyl hydroxylation and S-mephenytoin 4'-hydroxylation activities in livers of Japanese and Caucasian populations.
    Inoue K, Yamazaki H, Imiya K, Akasaka S, Guengerich FP, Shimada T.
    Pharmacogenetics; 1997 Apr 13; 7(2):103-13. PubMed ID: 9170147
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  • 11. Hepatic metabolism of tolbutamide: characterization of the form of cytochrome P-450 involved in methyl hydroxylation and relationship to in vivo disposition.
    Knodell RG, Hall SD, Wilkinson GR, Guengerich FP.
    J Pharmacol Exp Ther; 1987 Jun 13; 241(3):1112-9. PubMed ID: 3598900
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  • 13. Oxidation of tienilic acid by human yeast-expressed cytochromes P-450 2C8, 2C9, 2C18 and 2C19. Evidence that this drug is a mechanism-based inhibitor specific for cytochrome P-450 2C9.
    Jean P, Lopez-Garcia P, Dansette P, Mansuy D, Goldstein JL.
    Eur J Biochem; 1996 Nov 01; 241(3):797-804. PubMed ID: 8944768
    [Abstract] [Full Text] [Related]

  • 14. Isolation and characterization of human liver cytochrome P450 2C19: correlation between 2C19 and S-mephenytoin 4'-hydroxylation.
    Wrighton SA, Stevens JC, Becker GW, VandenBranden M.
    Arch Biochem Biophys; 1993 Oct 01; 306(1):240-5. PubMed ID: 8215410
    [Abstract] [Full Text] [Related]

  • 15. Formation of (R)-8-hydroxywarfarin in human liver microsomes. A new metabolic marker for the (S)-mephenytoin hydroxylase, P4502C19.
    Wienkers LC, Wurden CJ, Storch E, Kunze KL, Rettie AE, Trager WF.
    Drug Metab Dispos; 1996 May 01; 24(5):610-4. PubMed ID: 8723744
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  • 17. Participation of a rat liver cytochrome P-450 induced by pregnenolone 16 alpha-carbonitrile and other compounds in the 4-hydroxylation of mephenytoin.
    Shimada T, Guengerich FP.
    Mol Pharmacol; 1985 Aug 01; 28(2):215-9. PubMed ID: 4022003
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  • 20. Role of CYP2C19 in stereoselective hydroxylation of mephobarbital by human liver microsomes.
    Kobayashi K, Kogo M, Tani M, Shimada N, Ishizaki T, Numazawa S, Yoshida T, Yamamoto T, Kuroiwa Y, Chiba K.
    Drug Metab Dispos; 2001 Jan 01; 29(1):36-40. PubMed ID: 11124227
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