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Journal Abstract Search

124 related items for PubMed ID: 18579387

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  • 2. Selective alkylation of beta(II)-tubulin and thioredoxin-1 by structurally related subsets of aryl chloroethylureas leading to either anti-microtubules or redox modulating agents.
    Fortin JS, Côté MF, Lacroix J, Desjardins M, Petitclerc E, C-Gaudreault R.
    Bioorg Med Chem; 2008 Aug 01; 16(15):7277-90. PubMed ID: 18617414
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  • 3. Alkylation potency and protein specificity of aromatic urea derivatives and bioisosteres as potential irreversible antagonists of the colchicine-binding site.
    Fortin JS, Lacroix J, Desjardins M, Patenaude A, Petitclerc E, C-Gaudreault R.
    Bioorg Med Chem; 2007 Jul 01; 15(13):4456-69. PubMed ID: 17498960
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  • 4. Chloroethyl urea derivatives block tumour growth and thioredoxin-1 nuclear translocation.
    Patenaude A, Fortin JS, Deschenes R, Côté MF, Lacroix J, C-Gaudreault R, Petitclerc E.
    Can J Physiol Pharmacol; 2010 Nov 01; 88(11):1102-14. PubMed ID: 21076498
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  • 7. Alkylation of prohibitin by cyclohexylphenyl-chloroethyl urea on an aspartyl residue is associated with cell cycle G(1) arrest in B16 cells.
    Bouchon B, Papon J, Communal Y, Madelmont JC, Degoul F.
    Br J Pharmacol; 2007 Oct 01; 152(4):449-55. PubMed ID: 17704829
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  • 10. N-Phenyl-N'-(2-chloroethyl)ureas (CEU) as potential antineoplastic agents. Part 2: role of omega-hydroxyl group in the covalent binding to beta-tubulin.
    Fortin S, Moreau E, Patenaude A, Desjardins M, Lacroix J, Rousseau JL, C-Gaudreault R.
    Bioorg Med Chem; 2007 Feb 01; 15(3):1430-8. PubMed ID: 17118664
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  • 11. Design, synthesis and structure-activity relationships of antiproliferative 1,3-disubstituted urea derivatives.
    Li HQ, Zhu TT, Yan T, Luo Y, Zhu HL.
    Eur J Med Chem; 2009 Feb 01; 44(2):453-9. PubMed ID: 18514972
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  • 12. Optimized N-phenyl-N'-(2-chloroethyl)ureas as potential antineoplastic agents: synthesis and growth inhibition activity.
    Moreau E, Fortin S, Desjardins M, Rousseau JL, Petitclerc E, C-Gaudreault R.
    Bioorg Med Chem; 2005 Dec 15; 13(24):6703-12. PubMed ID: 16165366
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  • 13. N-Phenyl-N'-(2-chloroethyl)urea analogues of combretastatin A-4: Is the N-phenyl-N'-(2-chloroethyl)urea pharmacophore mimicking the trimethoxy phenyl moiety?
    Fortin S, Moreau E, Lacroix J, Teulade JC, Patenaude A, C-Gaudreault R.
    Bioorg Med Chem Lett; 2007 Apr 01; 17(7):2000-4. PubMed ID: 17291753
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  • 14. Synthesis and cytotoxic evaluation of substituted urea derivatives as inhibitors of human-leukemia K562 cells.
    Cao P, Huang XF, Ding H, Ge HM, Li HQ, Ruan BF, Zhu HL.
    Chem Biodivers; 2007 May 01; 4(5):881-6. PubMed ID: 17511003
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  • 15. Nitric oxide induces thioredoxin-1 nuclear translocation: possible association with the p21Ras survival pathway.
    Arai RJ, Masutani H, Yodoi J, Debbas V, Laurindo FR, Stern A, Monteiro HP.
    Biochem Biophys Res Commun; 2006 Oct 06; 348(4):1254-60. PubMed ID: 16914115
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  • 16. Mechanism of action of N-phenyl-N'-(2-chloroethyl)ureas in the colchicine-binding site at the interface between alpha- and beta-tubulin.
    Fortin S, Wei L, Moreau E, Labrie P, Petitclerc E, Kotra LP, C-Gaudreault R.
    Bioorg Med Chem; 2009 May 15; 17(10):3690-7. PubMed ID: 19398206
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  • 17. Synthesis and antitumor activity of ureas containing pyrimidinyl group.
    Jin C, Liang YJ, He H, Fu L.
    Eur J Med Chem; 2011 Jan 15; 46(1):429-32. PubMed ID: 21144621
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  • 18. Synthesis and antiproliferative evaluation of amide-containing flavone and isoflavone derivatives.
    Chen IL, Chen JY, Shieh PC, Chen JJ, Lee CH, Juang SH, Wang TC.
    Bioorg Med Chem; 2008 Aug 15; 16(16):7639-45. PubMed ID: 18662883
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  • 19. Synthesis and antiproliferative activity of 3-amino-N-phenyl-1H-indazole-1-carboxamides.
    Raffa D, Maggio B, Cascioferro S, Raimondi MV, Schillaci D, Gallo G, Daidone G, Plescia S, Meneghetti F, Bombieri G, Di Cristina A, Pipitone RM, Grimaudo S, Tolomeo M.
    Eur J Med Chem; 2009 Jan 15; 44(1):165-78. PubMed ID: 18485541
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  • 20. Anticancer activity of N-bis(trifluoromethyl)alkyl-N'-(polychlorophenyl) and N'-(1,2,4-triazolyl) ureas.
    Luzina EL, Popov AV.
    Eur J Med Chem; 2010 Nov 15; 45(11):5507-12. PubMed ID: 20850204
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