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Journal Abstract Search

264 related items for PubMed ID: 18587580

  • 1. CDDO-Me, a synthetic triterpenoid, inhibits expression of IL-6 and Stat3 phosphorylation in multi-drug resistant ovarian cancer cells.
    Duan Z, Ames RY, Ryan M, Hornicek FJ, Mankin H, Seiden MV.
    Cancer Chemother Pharmacol; 2009 Mar; 63(4):681-9. PubMed ID: 18587580
    [Abstract] [Full Text] [Related]

  • 2. Oleanane triterpenoid CDDO-Me induces apoptosis in multidrug resistant osteosarcoma cells through inhibition of Stat3 pathway.
    Ryu K, Susa M, Choy E, Yang C, Hornicek FJ, Mankin HJ, Duan Z.
    BMC Cancer; 2010 May 10; 10():187. PubMed ID: 20459702
    [Abstract] [Full Text] [Related]

  • 3. [Effects of siltuximab on the interleukin-6/Stat3 signaling pathway in ovarian cancer].
    Guo YQ, Lu P, Duan ZF, Zhang Z.
    Zhonghua Fu Chan Ke Za Zhi; 2010 Nov 10; 45(11):854-9. PubMed ID: 21211286
    [Abstract] [Full Text] [Related]

  • 4. The novel triterpenoid C-28 methyl ester of 2-cyano-3, 12-dioxoolen-1, 9-dien-28-oic acid inhibits metastatic murine breast tumor growth through inactivation of STAT3 signaling.
    Ling X, Konopleva M, Zeng Z, Ruvolo V, Stephens LC, Schober W, McQueen T, Dietrich M, Madden TL, Andreeff M.
    Cancer Res; 2007 May 01; 67(9):4210-8. PubMed ID: 17483332
    [Abstract] [Full Text] [Related]

  • 5. Bardoxolone Methyl Suppresses Hepatitis B Virus Large Surface Protein Variant W4P-Related Carcinogenesis and Hepatocellular Carcinoma Cell Proliferation Via the Inhibition of Signal Transducer and Activator of Transcription 3 Signaling.
    Gee MS, Kang SB, Kim N, Choi J, Kim NJ, Kim BJ, Inn KS, Lee JK.
    Pharmacology; 2018 May 01; 102(1-2):105-113. PubMed ID: 29953997
    [Abstract] [Full Text] [Related]

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  • 7. Synthetic oleanane triterpenoid, CDDO-Me, induces apoptosis in ovarian cancer cells by inhibiting prosurvival AKT/NF-κB/mTOR signaling.
    Gao X, Liu Y, Deeb D, Arbab AS, Guo AM, Dulchavsky SA, Gautam SC.
    Anticancer Res; 2011 Nov 01; 31(11):3673-81. PubMed ID: 22110186
    [Abstract] [Full Text] [Related]

  • 8. Signal transducers and activators of transcription 3 pathway activation in drug-resistant ovarian cancer.
    Duan Z, Foster R, Bell DA, Mahoney J, Wolak K, Vaidya A, Hampel C, Lee H, Seiden MV.
    Clin Cancer Res; 2006 Sep 01; 12(17):5055-63. PubMed ID: 16951221
    [Abstract] [Full Text] [Related]

  • 9. A synthetic triterpenoid, CDDO-Me, inhibits IkappaBalpha kinase and enhances apoptosis induced by TNF and chemotherapeutic agents through down-regulation of expression of nuclear factor kappaB-regulated gene products in human leukemic cells.
    Shishodia S, Sethi G, Konopleva M, Andreeff M, Aggarwal BB.
    Clin Cancer Res; 2006 Mar 15; 12(6):1828-38. PubMed ID: 16551868
    [Abstract] [Full Text] [Related]

  • 10. Triterpenoid CDDO-methyl ester inhibits the Janus-activated kinase-1 (JAK1)-->signal transducer and activator of transcription-3 (STAT3) pathway by direct inhibition of JAK1 and STAT3.
    Ahmad R, Raina D, Meyer C, Kufe D.
    Cancer Res; 2008 Apr 15; 68(8):2920-6. PubMed ID: 18413761
    [Abstract] [Full Text] [Related]

  • 11. Blockage of Stat3 with CDDO-Me inhibits tumor cell growth in chordoma.
    Yang C, Hornicek FJ, Wood KB, Schwab JH, Choy E, Mankin H, Duan Z.
    Spine (Phila Pa 1976); 2010 Aug 15; 35(18):1668-75. PubMed ID: 20386502
    [Abstract] [Full Text] [Related]

  • 12. ROS mediate proapoptotic and antisurvival activity of oleanane triterpenoid CDDO-Me in ovarian cancer cells.
    Gao X, Liu Y, Deeb D, Liu P, Liu A, Arbab AS, Gautam SC.
    Anticancer Res; 2013 Jan 15; 33(1):215-21. PubMed ID: 23267148
    [Abstract] [Full Text] [Related]

  • 13. Telomerase reverse transcriptase (TERT) is a therapeutic target of oleanane triterpenoid CDDO-Me in prostate cancer.
    Liu Y, Gao X, Deeb D, Arbab AS, Gautam SC.
    Molecules; 2012 Dec 11; 17(12):14795-809. PubMed ID: 23519253
    [Abstract] [Full Text] [Related]

  • 14. Inhibition of IL-6/STAT3 axis and targeting Axl and Tyro3 receptor tyrosine kinases by apigenin circumvent taxol resistance in ovarian cancer cells.
    Suh YA, Jo SY, Lee HY, Lee C.
    Int J Oncol; 2015 Mar 11; 46(3):1405-11. PubMed ID: 25544427
    [Abstract] [Full Text] [Related]

  • 15. Novel triterpenoid CDDO-Me is a potent inducer of apoptosis and differentiation in acute myelogenous leukemia.
    Konopleva M, Tsao T, Ruvolo P, Stiouf I, Estrov Z, Leysath CE, Zhao S, Harris D, Chang S, Jackson CE, Munsell M, Suh N, Gribble G, Honda T, May WS, Sporn MB, Andreeff M.
    Blood; 2002 Jan 01; 99(1):326-35. PubMed ID: 11756188
    [Abstract] [Full Text] [Related]

  • 16. Abrogation of constitutive Stat3 activity circumvents cisplatin resistant ovarian cancer.
    Ji T, Gong D, Han Z, Wei X, Yan Y, Ye F, Ding W, Wang J, Xia X, Li F, Hu W, Lu Y, Wang S, Zhou J, Ma D, Gao Q.
    Cancer Lett; 2013 Dec 01; 341(2):231-9. PubMed ID: 23962558
    [Abstract] [Full Text] [Related]

  • 17. 8-benzyl-4-oxo-8-azabicyclo[3.2.1]oct-2-ene-6,7-dicarboxylic acid (SD-1008), a novel janus kinase 2 inhibitor, increases chemotherapy sensitivity in human ovarian cancer cells.
    Duan Z, Bradner J, Greenberg E, Mazitschek R, Foster R, Mahoney J, Seiden MV.
    Mol Pharmacol; 2007 Nov 01; 72(5):1137-45. PubMed ID: 17675586
    [Abstract] [Full Text] [Related]

  • 18. Bardoxolone methyl induces apoptosis and autophagy and inhibits epithelial-to-mesenchymal transition and stemness in esophageal squamous cancer cells.
    Wang YY, Yang YX, Zhao R, Pan ST, Zhe H, He ZX, Duan W, Zhang X, Yang T, Qiu JX, Zhou SF.
    Drug Des Devel Ther; 2015 Nov 01; 9():993-1026. PubMed ID: 25733817
    [Abstract] [Full Text] [Related]

  • 19. CDDO-Me reveals USP7 as a novel target in ovarian cancer cells.
    Qin D, Wang W, Lei H, Luo H, Cai H, Tang C, Wu Y, Wang Y, Jin J, Xiao W, Wang T, Ma C, Xu H, Zhang J, Gao F, Wu YL.
    Oncotarget; 2016 Nov 22; 7(47):77096-77109. PubMed ID: 27780924
    [Abstract] [Full Text] [Related]

  • 20. Growth-inhibitory effect of a novel synthetic triterpenoid, 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid, on ovarian carcinoma cell lines not dependent on peroxisome proliferator-activated receptor-gamma expression.
    Melichar B, Konopleva M, Hu W, Melicharova K, Andreeff M, Freedman RS.
    Gynecol Oncol; 2004 Apr 22; 93(1):149-54. PubMed ID: 15047229
    [Abstract] [Full Text] [Related]

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