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Journal Abstract Search

221 related items for PubMed ID: 18593978

  • 1. DNA damage detection and repair pathways--recent advances with inhibitors of checkpoint kinases in cancer therapy.
    Ashwell S, Zabludoff S.
    Clin Cancer Res; 2008 Jul 01; 14(13):4032-7. PubMed ID: 18593978
    [Abstract] [Full Text] [Related]

  • 2. WEE1 kinase targeting combined with DNA-damaging cancer therapy catalyzes mitotic catastrophe.
    De Witt Hamer PC, Mir SE, Noske D, Van Noorden CJ, Würdinger T.
    Clin Cancer Res; 2011 Jul 01; 17(13):4200-7. PubMed ID: 21562035
    [Abstract] [Full Text] [Related]

  • 3. Targeting the cell cycle: a new approach to cancer therapy.
    Schwartz GK, Shah MA.
    J Clin Oncol; 2005 Dec 20; 23(36):9408-21. PubMed ID: 16361640
    [Abstract] [Full Text] [Related]

  • 4. Inhibitors of the G2 DNA damage checkpoint and their potential for cancer therapy.
    Anderson HJ, Andersen RJ, Roberge M.
    Prog Cell Cycle Res; 2003 Dec 20; 5():423-30. PubMed ID: 14593736
    [Abstract] [Full Text] [Related]

  • 5. AZD7762, a novel checkpoint kinase inhibitor, drives checkpoint abrogation and potentiates DNA-targeted therapies.
    Zabludoff SD, Deng C, Grondine MR, Sheehy AM, Ashwell S, Caleb BL, Green S, Haye HR, Horn CL, Janetka JW, Liu D, Mouchet E, Ready S, Rosenthal JL, Queva C, Schwartz GK, Taylor KJ, Tse AN, Walker GE, White AM.
    Mol Cancer Ther; 2008 Sep 20; 7(9):2955-66. PubMed ID: 18790776
    [Abstract] [Full Text] [Related]

  • 6. Targeting the S and G2 checkpoint to treat cancer.
    Chen T, Stephens PA, Middleton FK, Curtin NJ.
    Drug Discov Today; 2012 Mar 20; 17(5-6):194-202. PubMed ID: 22192883
    [Abstract] [Full Text] [Related]

  • 7. Targeting Wee1-like protein kinase to treat cancer.
    Stathis A, Oza A.
    Drug News Perspect; 2010 Sep 20; 23(7):425-9. PubMed ID: 20862394
    [Abstract] [Full Text] [Related]

  • 8. Dealing with DNA damage: relationships between checkpoint and repair pathways.
    Warmerdam DO, Kanaar R.
    Mutat Res; 2010 Sep 20; 704(1-3):2-11. PubMed ID: 20006736
    [Abstract] [Full Text] [Related]

  • 9. DNA structure and integrity checkpoints during the cell cycle and their role in drug targeting and sensitivity of tumor cells to anticancer treatment.
    Skladanowski A, Bozko P, Sabisz M.
    Chem Rev; 2009 Jul 20; 109(7):2951-73. PubMed ID: 19522503
    [No Abstract] [Full Text] [Related]

  • 10. A fundamental role for cell cycle regulation in the chemosensitivity of cancer cells?
    O'Connor PM, Kohn KW.
    Semin Cancer Biol; 1992 Dec 20; 3(6):409-16. PubMed ID: 1286161
    [Abstract] [Full Text] [Related]

  • 11. Targeted cancer therapies based on the inhibition of DNA strand break repair.
    O'Connor MJ, Martin NM, Smith GC.
    Oncogene; 2007 Dec 10; 26(56):7816-24. PubMed ID: 18066095
    [Abstract] [Full Text] [Related]

  • 12. Understanding DNA damage response and DNA repair pathways: applications to more targeted cancer therapeutics.
    Kinsella TJ.
    Semin Oncol; 2009 Apr 10; 36(2 Suppl 1):S42-51. PubMed ID: 19393835
    [Abstract] [Full Text] [Related]

  • 13. Checkpoint control and cancer.
    Medema RH, Macůrek L.
    Oncogene; 2012 May 24; 31(21):2601-13. PubMed ID: 21963855
    [Abstract] [Full Text] [Related]

  • 14. Improving the selectivity of cancer treatments by interfering with cell response pathways.
    Damia G, Broggini M.
    Eur J Cancer; 2004 Nov 24; 40(17):2550-9. PubMed ID: 15541958
    [Abstract] [Full Text] [Related]

  • 15. Implication of the G2 checkpoint in the maintenance of genome integrity.
    Piette J, Muñoz P.
    Pathol Biol (Paris); 2000 Apr 24; 48(3):174-81. PubMed ID: 10858951
    [Abstract] [Full Text] [Related]

  • 16. Apoptotic versus genotoxic potential of anti-tumor agents: a concept of duality in unity.
    Bajic V, Milicevic Z, Potpervic-Spremo B, Nedeljkovic-Kurepa A.
    Med Hypotheses; 2003 Apr 24; 61(5-6):643-50. PubMed ID: 14592801
    [Abstract] [Full Text] [Related]

  • 17. Checkpoint and coordinated cellular responses to DNA damage.
    Yang XH, Zou L.
    Results Probl Cell Differ; 2006 Apr 24; 42():65-92. PubMed ID: 16903208
    [Abstract] [Full Text] [Related]

  • 18. [Molecular mechanism regulating effect of anti-cancer agents].
    Saya H.
    Gan To Kagaku Ryoho; 2009 Jan 24; 36(1):1-5. PubMed ID: 19151557
    [Abstract] [Full Text] [Related]

  • 19. Differential toxicities of anticancer agents among DNA repair and checkpoint mutants of Saccharomyces cerevisiae.
    Simon JA, Szankasi P, Nguyen DK, Ludlow C, Dunstan HM, Roberts CJ, Jensen EL, Hartwell LH, Friend SH.
    Cancer Res; 2000 Jan 15; 60(2):328-33. PubMed ID: 10667584
    [Abstract] [Full Text] [Related]

  • 20. Regulation of DNA repair throughout the cell cycle.
    Branzei D, Foiani M.
    Nat Rev Mol Cell Biol; 2008 Apr 15; 9(4):297-308. PubMed ID: 18285803
    [Abstract] [Full Text] [Related]

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