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306 related items for PubMed ID: 18594209
1. Combination of rapamycin and 17-allylamino-17-demethoxygeldanamycin abrogates Akt activation and potentiates mTOR blockade in breast cancer cells. Roforth MM, Tan C. Anticancer Drugs; 2008 Aug; 19(7):681-8. PubMed ID: 18594209 [Abstract] [Full Text] [Related]
2. Combination mammalian target of rapamycin inhibitor rapamycin and HSP90 inhibitor 17-allylamino-17-demethoxygeldanamycin has synergistic activity in multiple myeloma. Francis LK, Alsayed Y, Leleu X, Jia X, Singha UK, Anderson J, Timm M, Ngo H, Lu G, Huston A, Ehrlich LA, Dimmock E, Lentzsch S, Hideshima T, Roodman GD, Anderson KC, Ghobrial IM. Clin Cancer Res; 2006 Nov 15; 12(22):6826-35. PubMed ID: 17121904 [Abstract] [Full Text] [Related]
3. Nitric oxide in physiologic concentrations targets the translational machinery to increase the proliferation of human breast cancer cells: involvement of mammalian target of rapamycin/eIF4E pathway. Pervin S, Singh R, Hernandez E, Wu G, Chaudhuri G. Cancer Res; 2007 Jan 01; 67(1):289-99. PubMed ID: 17210710 [Abstract] [Full Text] [Related]
4. The heat shock protein 90 inhibitor, 17-allylamino-17-demethoxygeldanamycin, enhances osteoclast formation and potentiates bone metastasis of a human breast cancer cell line. Price JT, Quinn JM, Sims NA, Vieusseux J, Waldeck K, Docherty SE, Myers D, Nakamura A, Waltham MC, Gillespie MT, Thompson EW. Cancer Res; 2005 Jun 01; 65(11):4929-38. PubMed ID: 15930315 [Abstract] [Full Text] [Related]
5. Targeted therapy of human osteosarcoma with 17AAG or rapamycin: characterization of induced apoptosis and inhibition of mTOR and Akt/MAPK/Wnt pathways. Gazitt Y, Kolaparthi V, Moncada K, Thomas C, Freeman J. Int J Oncol; 2009 Feb 01; 34(2):551-61. PubMed ID: 19148492 [Abstract] [Full Text] [Related]
6. Acetaldehyde promotes rapamycin-dependent activation of p70(S6K) and glucose uptake despite inhibition of Akt and mTOR in dopaminergic SH-SY5Y human neuroblastoma cells. Fang CX, Yang X, Sreejayan N, Ren J. Exp Neurol; 2007 Jan 01; 203(1):196-204. PubMed ID: 16962100 [Abstract] [Full Text] [Related]
7. Mammalian target of rapamycin, a molecular target in squamous cell carcinomas of the head and neck. Amornphimoltham P, Patel V, Sodhi A, Nikitakis NG, Sauk JJ, Sausville EA, Molinolo AA, Gutkind JS. Cancer Res; 2005 Nov 01; 65(21):9953-61. PubMed ID: 16267020 [Abstract] [Full Text] [Related]
10. Formation of 17-allylamino-demethoxygeldanamycin (17-AAG) hydroquinone by NAD(P)H:quinone oxidoreductase 1: role of 17-AAG hydroquinone in heat shock protein 90 inhibition. Guo W, Reigan P, Siegel D, Zirrolli J, Gustafson D, Ross D. Cancer Res; 2005 Nov 01; 65(21):10006-15. PubMed ID: 16267026 [Abstract] [Full Text] [Related]
11. IGF-1-stimulated protein synthesis in oligodendrocyte progenitors requires PI3K/mTOR/Akt and MEK/ERK pathways. Bibollet-Bahena O, Almazan G. J Neurochem; 2009 Jun 01; 109(5):1440-51. PubMed ID: 19453943 [Abstract] [Full Text] [Related]
12. Inhibition of heat shock protein 90 function down-regulates Akt kinase and sensitizes tumors to Taxol. Solit DB, Basso AD, Olshen AB, Scher HI, Rosen N. Cancer Res; 2003 May 01; 63(9):2139-44. PubMed ID: 12727831 [Abstract] [Full Text] [Related]
13. Rapamycin inhibits proliferation of estrogen-receptor-positive breast cancer cells. Chang SB, Miron P, Miron A, Iglehart JD. J Surg Res; 2007 Mar 01; 138(1):37-44. PubMed ID: 17109887 [Abstract] [Full Text] [Related]
14. Coadministration of the heat shock protein 90 antagonist 17-allylamino- 17-demethoxygeldanamycin with suberoylanilide hydroxamic acid or sodium butyrate synergistically induces apoptosis in human leukemia cells. Rahmani M, Yu C, Dai Y, Reese E, Ahmed W, Dent P, Grant S. Cancer Res; 2003 Dec 01; 63(23):8420-7. PubMed ID: 14679005 [Abstract] [Full Text] [Related]
19. Hormone-refractory breast cancer remains sensitive to the antitumor activity of heat shock protein 90 inhibitors. Beliakoff J, Bagatell R, Paine-Murrieta G, Taylor CW, Lykkesfeldt AE, Whitesell L. Clin Cancer Res; 2003 Oct 15; 9(13):4961-71. PubMed ID: 14581371 [Abstract] [Full Text] [Related]
20. The heat-shock protein 90 inhibitor, geldanamycin, induces apoptotic cell death in Epstein-Barr virus-positive NK/T-cell lymphoma by Akt down-regulation. Jeon YK, Park CH, Kim KY, Li YC, Kim J, Kim YA, Paik JH, Park BK, Kim CW, Kim YN. J Pathol; 2007 Oct 15; 213(2):170-9. PubMed ID: 17768706 [Abstract] [Full Text] [Related] Page: [Next] [New Search]