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Journal Abstract Search

420 related items for PubMed ID: 18595690

  • 1.
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  • 2. Benzyl amide-ketoacid inhibitors of HIV-integrase.
    Walker MA, Johnson T, Naidu BN, Banville J, Remillard R, Plamondon S, Martel A, Li C, Torri A, Samanta H, Lin Z, Dicker I, Krystal M, Meanwell NA.
    Bioorg Med Chem Lett; 2007 Sep 01; 17(17):4886-90. PubMed ID: 17604626
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  • 4. Synthesis of 5-(1-H or 1-alkyl-5-oxopyrrolidin-3-yl)-8-hydroxy-[1,6]-naphthyridine-7-carboxamide inhibitors of HIV-1 integrase.
    Melamed JY, Egbertson MS, Varga S, Vacca JP, Moyer G, Gabryelski L, Felock PJ, Stillmock KA, Witmer MV, Schleif W, Hazuda DJ, Leonard Y, Jin L, Ellis JD, Young SD.
    Bioorg Med Chem Lett; 2008 Oct 01; 18(19):5307-10. PubMed ID: 18774711
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  • 6. Rational design of 2-pyrrolinones as inhibitors of HIV-1 integrase.
    Ma K, Wang P, Fu W, Wan X, Zhou L, Chu Y, Ye D.
    Bioorg Med Chem Lett; 2011 Nov 15; 21(22):6724-7. PubMed ID: 21996518
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  • 7. Amide-containing diketoacids as HIV-1 integrase inhibitors: synthesis, structure-activity relationship analysis, and biological activity.
    Li H, Wang C, Sanchez T, Tan Y, Jiang C, Neamati N, Zhao G.
    Bioorg Med Chem; 2009 Apr 01; 17(7):2913-9. PubMed ID: 19269185
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  • 8. N-(4-Fluorobenzyl)-3-hydroxy-9,9-dimethyl-4-oxo-6,7,8,9-tetrahydro-4H-pyrazino[1,2-a]pyrimidine-2-carboxamides a novel class of potent HIV-1 integrase inhibitors.
    Petrocchi A, Jones P, Rowley M, Fiore F, Summa V.
    Bioorg Med Chem Lett; 2009 Aug 01; 19(15):4245-9. PubMed ID: 19523819
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  • 14. A platform for designing HIV integrase inhibitors. Part 2: a two-metal binding model as a potential mechanism of HIV integrase inhibitors.
    Kawasuji T, Fuji M, Yoshinaga T, Sato A, Fujiwara T, Kiyama R.
    Bioorg Med Chem; 2006 Dec 15; 14(24):8420-9. PubMed ID: 17005407
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  • 15. Pharmacophore and structure-activity relationships of integrase inhibition within a dual inhibitor scaffold of HIV reverse transcriptase and integrase.
    Wang Z, Tang J, Salomon CE, Dreis CD, Vince R.
    Bioorg Med Chem; 2010 Jun 15; 18(12):4202-11. PubMed ID: 20576573
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  • 16. A refined pharmacophore model for HIV-1 integrase inhibitors: Optimization of potency in the 1H-benzylindole series.
    De Luca L, Barreca ML, Ferro S, Iraci N, Michiels M, Christ F, Debyser Z, Witvrouw M, Chimirri A.
    Bioorg Med Chem Lett; 2008 May 01; 18(9):2891-5. PubMed ID: 18417342
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  • 18. Synthesis, biological evaluation and molecular modeling studies of quinolonyl diketo acid derivatives: new structural insight into the HIV-1 integrase inhibition.
    Vandurm P, Guiguen A, Cauvin C, Georges B, Le Van K, Michaux C, Cardona C, Mbemba G, Mouscadet JF, Hevesi L, Van Lint C, Wouters J.
    Eur J Med Chem; 2011 May 01; 46(5):1749-56. PubMed ID: 21385662
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  • 19. Synthesis and biological evaluation of purine derivatives incorporating metal chelating ligands as HIV integrase inhibitors.
    Li X, Vince R.
    Bioorg Med Chem; 2006 Aug 15; 14(16):5742-55. PubMed ID: 16753300
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  • 20. Synthesis, antiviral, and anti-HIV-1 integrase activities of 3-aroyl-1,1-dioxo-1,4,2-benzodithiazines.
    Brzozowski Z, Saczewski F, Sanchez T, Kuo CL, Gdaniec M, Neamati N.
    Bioorg Med Chem; 2004 Jul 01; 12(13):3663-72. PubMed ID: 15186851
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