These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Journal Abstract Search

314 related items for PubMed ID: 18597780

  • 1. Effect of flap mutations on structure of HIV-1 protease and inhibition by saquinavir and darunavir.
    Liu F, Kovalevsky AY, Tie Y, Ghosh AK, Harrison RW, Weber IT.
    J Mol Biol; 2008 Aug 01; 381(1):102-15. PubMed ID: 18597780
    [Abstract] [Full Text] [Related]

  • 2. Amprenavir complexes with HIV-1 protease and its drug-resistant mutants altering hydrophobic clusters.
    Shen CH, Wang YF, Kovalevsky AY, Harrison RW, Weber IT.
    FEBS J; 2010 Sep 01; 277(18):3699-714. PubMed ID: 20695887
    [Abstract] [Full Text] [Related]

  • 3.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 4.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 5. Insight into analysis of interactions of saquinavir with HIV-1 protease in comparison between the wild-type and G48V and G48V/L90M mutants based on QM and QM/MM calculations.
    Saen-oon S, Aruksakunwong O, Wittayanarakul K, Sompornpisut P, Hannongbua S.
    J Mol Graph Model; 2007 Nov 01; 26(4):720-7. PubMed ID: 17543558
    [Abstract] [Full Text] [Related]

  • 6. A contribution to the drug resistance mechanism of darunavir, amprenavir, indinavir, and saquinavir complexes with HIV-1 protease due to flap mutation I50V: a systematic MM-PBSA and thermodynamic integration study.
    Leonis G, Steinbrecher T, Papadopoulos MG.
    J Chem Inf Model; 2013 Aug 26; 53(8):2141-53. PubMed ID: 23834142
    [Abstract] [Full Text] [Related]

  • 7. Critical differences in HIV-1 and HIV-2 protease specificity for clinical inhibitors.
    Tie Y, Wang YF, Boross PI, Chiu TY, Ghosh AK, Tozser J, Louis JM, Harrison RW, Weber IT.
    Protein Sci; 2012 Mar 26; 21(3):339-50. PubMed ID: 22238126
    [Abstract] [Full Text] [Related]

  • 8. Atomic resolution crystal structures of HIV-1 protease and mutants V82A and I84V with saquinavir.
    Tie Y, Kovalevsky AY, Boross P, Wang YF, Ghosh AK, Tozser J, Harrison RW, Weber IT.
    Proteins; 2007 Apr 01; 67(1):232-42. PubMed ID: 17243183
    [Abstract] [Full Text] [Related]

  • 9. Structural Studies of a Rationally Selected Multi-Drug Resistant HIV-1 Protease Reveal Synergistic Effect of Distal Mutations on Flap Dynamics.
    Agniswamy J, Louis JM, Roche J, Harrison RW, Weber IT.
    PLoS One; 2016 Apr 01; 11(12):e0168616. PubMed ID: 27992544
    [Abstract] [Full Text] [Related]

  • 10.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 11.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 12.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 13.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 14.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 15.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 16.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 17.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 18. Structures of darunavir-resistant HIV-1 protease mutant reveal atypical binding of darunavir to wide open flaps.
    Zhang Y, Chang YC, Louis JM, Wang YF, Harrison RW, Weber IT.
    ACS Chem Biol; 2014 Jun 20; 9(6):1351-8. PubMed ID: 24738918
    [Abstract] [Full Text] [Related]

  • 19. The L76V drug resistance mutation decreases the dimer stability and rate of autoprocessing of HIV-1 protease by reducing internal hydrophobic contacts.
    Louis JM, Zhang Y, Sayer JM, Wang YF, Harrison RW, Weber IT.
    Biochemistry; 2011 May 31; 50(21):4786-95. PubMed ID: 21446746
    [Abstract] [Full Text] [Related]

  • 20. Defective hydrophobic sliding mechanism and active site expansion in HIV-1 protease drug resistant variant Gly48Thr/Leu89Met: mechanisms for the loss of saquinavir binding potency.
    Goldfarb NE, Ohanessian M, Biswas S, McGee TD, Mahon BP, Ostrov DA, Garcia J, Tang Y, McKenna R, Roitberg A, Dunn BM.
    Biochemistry; 2015 Jan 20; 54(2):422-33. PubMed ID: 25513833
    [Abstract] [Full Text] [Related]

    Page: [Next] [New Search]
    of 16.