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290 related items for PubMed ID: 18600054

  • 1. Characterization of tailoring genes involved in the modification of geldanamycin polyketide in Streptomyces hygroscopicus JCM4427.
    Shin JC, Na Z, Lee DH, Kim WC, Lee K, Shen YM, Paik SG, Hong YS, Lee JJ.
    J Microbiol Biotechnol; 2008 Jun; 18(6):1101-8. PubMed ID: 18600054
    [Abstract] [Full Text] [Related]

  • 2. Inactivation of putative PKS genes can double geldanamycin yield in Streptomyces hygroscopicus 17997.
    Li YH, Li M, He WQ, Wang YG, Shao RG.
    Genet Mol Res; 2013 Jun 21; 12(2):2076-85. PubMed ID: 23913387
    [Abstract] [Full Text] [Related]

  • 3. The LuxR family members GdmRI and GdmRII are positive regulators of geldanamycin biosynthesis in Streptomyces hygroscopicus 17997.
    He W, Lei J, Liu Y, Wang Y.
    Arch Microbiol; 2008 May 21; 189(5):501-10. PubMed ID: 18214443
    [Abstract] [Full Text] [Related]

  • 4. [Establishment of gene transduction system in geldanamycin producer - Streptomyces hygroscopicus 17997 and its application for gene disruption experiment].
    Gao HY, Wang YG, Gao QJ, Shang GD, Sun GZ, Yang Y.
    Sheng Wu Gong Cheng Xue Bao; 2003 Jul 21; 19(4):407-11. PubMed ID: 15969055
    [Abstract] [Full Text] [Related]

  • 5. A new post-PKS modification process in the carbamoyltransferase gene inactivation strain of Streptomyces hygroscopicus 17997.
    Li Y, He W, Wang Y, Wang Y, Shao R.
    J Antibiot (Tokyo); 2008 Jun 21; 61(6):347-55. PubMed ID: 18667782
    [Abstract] [Full Text] [Related]

  • 6. Rational biosynthetic engineering for optimization of geldanamycin analogues.
    Kim W, Lee D, Hong SS, Na Z, Shin JC, Roh SH, Wu CZ, Choi O, Lee K, Shen YM, Paik SG, Lee JJ, Hong YS.
    Chembiochem; 2009 May 04; 10(7):1243-51. PubMed ID: 19308924
    [Abstract] [Full Text] [Related]

  • 7. Inactivation of the carbamoyltransferase gene refines post-polyketide synthase modification steps in the biosynthesis of the antitumor agent geldanamycin.
    Hong YS, Lee D, Kim W, Jeong JK, Kim CG, Sohng JK, Lee JH, Paik SG, Lee JJ.
    J Am Chem Soc; 2004 Sep 15; 126(36):11142-3. PubMed ID: 15355082
    [Abstract] [Full Text] [Related]

  • 8. Identification of three positive regulators in the geldanamycin PKS gene cluster of Streptomyces hygroscopicus JCM4427.
    Kim W, Lee JJ, Paik SG, Hong YS.
    J Microbiol Biotechnol; 2010 Nov 15; 20(11):1484-90. PubMed ID: 21124051
    [Abstract] [Full Text] [Related]

  • 9. Insights into the biosynthesis of the benzoquinone ansamycins geldanamycin and herbimycin, obtained by gene sequencing and disruption.
    Rascher A, Hu Z, Buchanan GO, Reid R, Hutchinson CR.
    Appl Environ Microbiol; 2005 Aug 15; 71(8):4862-71. PubMed ID: 16085885
    [Abstract] [Full Text] [Related]

  • 10. Improved PKS Gene Expression With Strong Endogenous Promoter Resulted in Geldanamycin Yield Increase.
    Wang X, Ning X, Zhao Q, Kang Q, Bai L.
    Biotechnol J; 2017 Nov 15; 12(11):. PubMed ID: 28731630
    [Abstract] [Full Text] [Related]

  • 11. [Roles of geldanamycin biosynthetic genes in Streptomyces hygroscopicus 17997].
    He W, Liu Y, Sun G, Wang Y.
    Sheng Wu Gong Cheng Xue Bao; 2008 Jul 15; 24(7):1133-9. PubMed ID: 18837385
    [Abstract] [Full Text] [Related]

  • 12. Engineered biosynthesis of geldanamycin analogs for Hsp90 inhibition.
    Patel K, Piagentini M, Rascher A, Tian ZQ, Buchanan GO, Regentin R, Hu Z, Hutchinson CR, McDaniel R.
    Chem Biol; 2004 Dec 15; 11(12):1625-33. PubMed ID: 15610846
    [Abstract] [Full Text] [Related]

  • 13. Enhancement of geldanamycin production by pH shock in batch culture of Streptomyces hygroscopicus subsp. duamyceticus.
    Song JY, Kim YJ, Hong YS, Chang YK.
    J Microbiol Biotechnol; 2008 May 15; 18(5):897-900. PubMed ID: 18633288
    [Abstract] [Full Text] [Related]

  • 14. Characterization of biosynthetic gene cluster for the production of virginiamycin M, a streptogramin type A antibiotic, in Streptomyces virginiae.
    Pulsawat N, Kitani S, Nihira T.
    Gene; 2007 May 15; 393(1-2):31-42. PubMed ID: 17350183
    [Abstract] [Full Text] [Related]

  • 15. New geldanamycin analogs from Streptomyces hygroscopicus.
    Wu CZ, Jang JH, Ahn JS, Hong YS.
    J Microbiol Biotechnol; 2012 Nov 15; 22(11):1478-81. PubMed ID: 23124337
    [Abstract] [Full Text] [Related]

  • 16. Features of the Streptomyces hygroscopicus HtpG reveal how partial geldanamycin resistance can arise with mutation to the ATP binding pocket of a eukaryotic Hsp90.
    Millson SH, Chua CS, Roe SM, Polier S, Solovieva S, Pearl LH, Sim TS, Prodromou C, Piper PW.
    FASEB J; 2011 Nov 15; 25(11):3828-37. PubMed ID: 21778327
    [Abstract] [Full Text] [Related]

  • 17. Chalcomycin biosynthesis gene cluster from Streptomyces bikiniensis: novel features of an unusual ketolide produced through expression of the chm polyketide synthase in Streptomyces fradiae.
    Ward SL, Hu Z, Schirmer A, Reid R, Revill WP, Reeves CD, Petrakovsky OV, Dong SD, Katz L.
    Antimicrob Agents Chemother; 2004 Dec 15; 48(12):4703-12. PubMed ID: 15561847
    [Abstract] [Full Text] [Related]

  • 18. Novel 4,5-dihydro-thiazinogeldanamycin in a gdmP mutant strain of Streptomyces hygroscopicus 17997.
    Lin L, Ni S, Wu L, Wang Y, Wang Y, Tao P, He W, Wang X.
    Biosci Biotechnol Biochem; 2011 Dec 15; 75(10):2042-5. PubMed ID: 21979086
    [Abstract] [Full Text] [Related]

  • 19. [Cloning and analysis of geldanamycin partial biosynthetic gene cluster of Streptomyces hygroscopicus 17997].
    He WQ, Wang YG.
    Sheng Wu Gong Cheng Xue Bao; 2006 Nov 15; 22(6):902-6. PubMed ID: 17168310
    [Abstract] [Full Text] [Related]

  • 20. Characterization of Gel16 as a Cytochrome P450 in Geldanamycin Biosynthesis and in-silico Analysis for an Endogenous Electron Transport System.
    Rimal H, Yu SC, Lee B, Hong YS, Oh TJ.
    J Microbiol Biotechnol; 2019 Jan 28; 29(1):44-54. PubMed ID: 30415526
    [Abstract] [Full Text] [Related]

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