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Journal Abstract Search

821 related items for PubMed ID: 18600270

  • 1. Carbonic anhydrase inhibitors. Sulfonamide diuretics revisited--old leads for new applications?
    Temperini C, Cecchi A, Scozzafava A, Supuran CT.
    Org Biomol Chem; 2008 Jul 21; 6(14):2499-506. PubMed ID: 18600270
    [Abstract] [Full Text] [Related]

  • 2. Carbonic anhydrase inhibitors. Interaction of indapamide and related diuretics with 12 mammalian isozymes and X-ray crystallographic studies for the indapamide-isozyme II adduct.
    Temperini C, Cecchi A, Scozzafava A, Supuran CT.
    Bioorg Med Chem Lett; 2008 Apr 15; 18(8):2567-73. PubMed ID: 18374572
    [Abstract] [Full Text] [Related]

  • 3. Carbonic anhydrase inhibitors. Comparison of chlorthalidone, indapamide, trichloromethiazide, and furosemide X-ray crystal structures in adducts with isozyme II, when several water molecules make the difference.
    Temperini C, Cecchi A, Scozzafava A, Supuran CT.
    Bioorg Med Chem; 2009 Feb 01; 17(3):1214-21. PubMed ID: 19119014
    [Abstract] [Full Text] [Related]

  • 4. Diuretics: from classical carbonic anhydrase inhibitors to novel applications of the sulfonamides.
    Supuran CT.
    Curr Pharm Des; 2008 Feb 01; 14(7):641-8. PubMed ID: 18336309
    [Abstract] [Full Text] [Related]

  • 5. Carbonic anhydrase inhibitors. Interaction of 2-(hydrazinocarbonyl)-3-phenyl-1H-indole-5-sulfonamide with 12 mammalian isoforms: kinetic and X-ray crystallographic studies.
    Güzel O, Temperini C, Innocenti A, Scozzafava A, Salman A, Supuran CT.
    Bioorg Med Chem Lett; 2008 Jan 01; 18(1):152-8. PubMed ID: 18024029
    [Abstract] [Full Text] [Related]

  • 6. Sulfonamides incorporating 1,3,5-triazine moieties selectively and potently inhibit carbonic anhydrase transmembrane isoforms IX, XII and XIV over cytosolic isoforms I and II: Solution and X-ray crystallographic studies.
    Carta F, Garaj V, Maresca A, Wagner J, Avvaru BS, Robbins AH, Scozzafava A, McKenna R, Supuran CT.
    Bioorg Med Chem; 2011 May 15; 19(10):3105-19. PubMed ID: 21515057
    [Abstract] [Full Text] [Related]

  • 7. Carbonic anhydrase inhibitors. Comparison of chlorthalidone and indapamide X-ray crystal structures in adducts with isozyme II: when three water molecules and the keto-enol tautomerism make the difference.
    Temperini C, Cecchi A, Scozzafava A, Supuran CT.
    J Med Chem; 2009 Jan 22; 52(2):322-8. PubMed ID: 19115843
    [Abstract] [Full Text] [Related]

  • 8. Carbonic anhydrase inhibitors. Interaction of 2-N,N-dimethylamino-1,3,4-thiadiazole-5-methanesulfonamide with 12 mammalian isoforms: kinetic and X-ray crystallographic studies.
    Temperini C, Cecchi A, Boyle NA, Scozzafava A, Cabeza JE, Wentworth P, Blackburn GM, Supuran CT.
    Bioorg Med Chem Lett; 2008 Feb 01; 18(3):999-1005. PubMed ID: 18162396
    [Abstract] [Full Text] [Related]

  • 9. Designing of novel carbonic anhydrase inhibitors and activators.
    Supuran CT, Vullo D, Manole G, Casini A, Scozzafava A.
    Curr Med Chem Cardiovasc Hematol Agents; 2004 Jan 01; 2(1):49-68. PubMed ID: 15328829
    [Abstract] [Full Text] [Related]

  • 10. Carbonic anhydrase inhibitors: Valdecoxib binds to a different active site region of the human isoform II as compared to the structurally related cyclooxygenase II "selective" inhibitor celecoxib.
    Di Fiore A, Pedone C, D'Ambrosio K, Scozzafava A, De Simone G, Supuran CT.
    Bioorg Med Chem Lett; 2006 Jan 15; 16(2):437-42. PubMed ID: 16290146
    [Abstract] [Full Text] [Related]

  • 11. New chemotypes acting as isozyme-selective carbonic anhydrase inhibitors with low affinity for the offtarget cytosolic isoform II.
    Carta F, Vullo D, Maresca A, Scozzafava A, Supuran CT.
    Bioorg Med Chem Lett; 2012 Mar 15; 22(6):2182-5. PubMed ID: 22365761
    [Abstract] [Full Text] [Related]

  • 12. S-glycosyl primary sulfonamides--a new structural class for selective inhibition of cancer-associated carbonic anhydrases.
    Lopez M, Paul B, Hofmann A, Morizzi J, Wu QK, Charman SA, Innocenti A, Vullo D, Supuran CT, Poulsen SA.
    J Med Chem; 2009 Oct 22; 52(20):6421-32. PubMed ID: 19827837
    [Abstract] [Full Text] [Related]

  • 13. Carbonic anhydrase inhibitors: interactions of phenols with the 12 catalytically active mammalian isoforms (CA I-XIV).
    Innocenti A, Vullo D, Scozzafava A, Supuran CT.
    Bioorg Med Chem Lett; 2008 Mar 01; 18(5):1583-7. PubMed ID: 18242985
    [Abstract] [Full Text] [Related]

  • 14. Diuretics with carbonic anhydrase inhibitory action: a patent and literature review (2005 - 2013).
    Carta F, Supuran CT.
    Expert Opin Ther Pat; 2013 Mar 01; 23(6):681-91. PubMed ID: 23488823
    [Abstract] [Full Text] [Related]

  • 15. Indapamide-like benzenesulfonamides as inhibitors of carbonic anhydrases I, II, VII, and XIII.
    Čapkauskaitė E, Baranauskienė L, Golovenko D, Manakova E, Gražulis S, Tumkevičius S, Matulis D.
    Bioorg Med Chem; 2010 Nov 01; 18(21):7357-64. PubMed ID: 20926301
    [Abstract] [Full Text] [Related]

  • 16. Carbonic anhydrase inhibitors: inhibition of human cytosolic isozymes I and II and tumor-associated isozymes IX and XII with S-substituted 4-chloro-2-mercapto-5-methyl-benzenesulfonamides.
    Saczewski F, Innocenti A, Sławiński J, Kornicka A, Brzozowski Z, Pomarnacka E, Scozzafava A, Temperini C, Supuran CT.
    Bioorg Med Chem; 2008 Apr 01; 16(7):3933-40. PubMed ID: 18242998
    [Abstract] [Full Text] [Related]

  • 17. Carbonic anhydrase inhibitors: inhibition of mammalian isoforms I-XIV with a series of substituted phenols including paracetamol and salicylic acid.
    Innocenti A, Vullo D, Scozzafava A, Supuran CT.
    Bioorg Med Chem; 2008 Aug 01; 16(15):7424-8. PubMed ID: 18579385
    [Abstract] [Full Text] [Related]

  • 18. Conformational variability of different sulfonamide inhibitors with thienyl-acetamido moieties attributes to differential binding in the active site of cytosolic human carbonic anhydrase isoforms.
    Biswas S, Aggarwal M, Güzel Ö, Scozzafava A, McKenna R, Supuran CT.
    Bioorg Med Chem; 2011 Jun 15; 19(12):3732-8. PubMed ID: 21620713
    [Abstract] [Full Text] [Related]

  • 19. 5-Substituted-(1,2,3-triazol-4-yl)thiophene-2-sulfonamides strongly inhibit human carbonic anhydrases I, II, IX and XII: solution and X-ray crystallographic studies.
    Leitans J, Sprudza A, Tanc M, Vozny I, Zalubovskis R, Tars K, Supuran CT.
    Bioorg Med Chem; 2013 Sep 01; 21(17):5130-8. PubMed ID: 23859774
    [Abstract] [Full Text] [Related]

  • 20. 4-Substituted-2,3,5,6-tetrafluorobenzenesulfonamides as inhibitors of carbonic anhydrases I, II, VII, XII, and XIII.
    Dudutienė V, Zubrienė A, Smirnov A, Gylytė J, Timm D, Manakova E, Gražulis S, Matulis D.
    Bioorg Med Chem; 2013 Apr 01; 21(7):2093-106. PubMed ID: 23394791
    [Abstract] [Full Text] [Related]

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