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188 related items for PubMed ID: 18602919

  • 1. B-Raf(V600E) cooperates with alternative spliced Rac1b to sustain colorectal cancer cell survival.
    Matos P, Oliveira C, Velho S, Gonçalves V, da Costa LT, Moyer MP, Seruca R, Jordan P.
    Gastroenterology; 2008 Sep; 135(3):899-906. PubMed ID: 18602919
    [Abstract] [Full Text] [Related]

  • 2. BRAF provides proliferation and survival signals in MSI colorectal carcinoma cells displaying BRAF(V600E) but not KRAS mutations.
    Preto A, Figueiredo J, Velho S, Ribeiro AS, Soares P, Oliveira C, Seruca R.
    J Pathol; 2008 Feb; 214(3):320-7. PubMed ID: 18098337
    [Abstract] [Full Text] [Related]

  • 3. Increased Rac1b expression sustains colorectal tumor cell survival.
    Matos P, Jordan P.
    Mol Cancer Res; 2008 Jul; 6(7):1178-84. PubMed ID: 18644982
    [Abstract] [Full Text] [Related]

  • 4. RAC1b overexpression correlates with poor prognosis in KRAS/BRAF WT metastatic colorectal cancer patients treated with first-line FOLFOX/XELOX chemotherapy.
    Alonso-Espinaco V, Cuatrecasas M, Alonso V, Escudero P, Marmol M, Horndler C, Ortego J, Gallego R, Codony-Servat J, Garcia-Albeniz X, Jares P, Castells A, Lozano JJ, Rosell R, Maurel J.
    Eur J Cancer; 2014 Jul; 50(11):1973-81. PubMed ID: 24833563
    [Abstract] [Full Text] [Related]

  • 5. Oncogenic Ras, but not (V600E)B-RAF, protects from cholesterol depletion-induced apoptosis through the PI3K/AKT pathway in colorectal cancer cells.
    Calleros L, Sánchez-Hernández I, Baquero P, Toro MJ, Chiloeches A.
    Carcinogenesis; 2009 Oct; 30(10):1670-7. PubMed ID: 19700418
    [Abstract] [Full Text] [Related]

  • 6. Antagonistic SR proteins regulate alternative splicing of tumor-related Rac1b downstream of the PI3-kinase and Wnt pathways.
    Gonçalves V, Matos P, Jordan P.
    Hum Mol Genet; 2009 Oct 01; 18(19):3696-707. PubMed ID: 19602482
    [Abstract] [Full Text] [Related]

  • 7. Expression of tumor-related Rac1b antagonizes B-Raf-induced senescence in colorectal cells.
    Henriques AF, Barros P, Moyer MP, Matos P, Jordan P.
    Cancer Lett; 2015 Dec 28; 369(2):368-75. PubMed ID: 26341689
    [Abstract] [Full Text] [Related]

  • 8. Concomitant mutations and splice variants in KRAS and BRAF demonstrate complex perturbation of the Ras/Raf signalling pathway in advanced colorectal cancer.
    Seth R, Crook S, Ibrahem S, Fadhil W, Jackson D, Ilyas M.
    Gut; 2009 Sep 28; 58(9):1234-41. PubMed ID: 19474002
    [Abstract] [Full Text] [Related]

  • 9. Similarity of the phenotypic patterns associated with BRAF and KRAS mutations in colorectal neoplasia.
    Yuen ST, Davies H, Chan TL, Ho JW, Bignell GR, Cox C, Stephens P, Edkins S, Tsui WW, Chan AS, Futreal PA, Stratton MR, Wooster R, Leung SY.
    Cancer Res; 2002 Nov 15; 62(22):6451-5. PubMed ID: 12438234
    [Abstract] [Full Text] [Related]

  • 10. Oligonucleotide microarray analysis of distinct gene expression patterns in colorectal cancer tissues harboring BRAF and K-ras mutations.
    Kim IJ, Kang HC, Jang SG, Kim K, Ahn SA, Yoon HJ, Yoon SN, Park JG.
    Carcinogenesis; 2006 Mar 15; 27(3):392-404. PubMed ID: 16219636
    [Abstract] [Full Text] [Related]

  • 11. Analysis of the K-ras/B-raf/Erk signal cascade, p53 and CMAP as markers for tumor progression in colorectal cancer patients.
    Georgieva M, Krasteva M, Angelova E, Ralchev K, Dimitrov V, Bozhimirov S, Georgieva E, Berger MR.
    Oncol Rep; 2008 Jul 15; 20(1):3-11. PubMed ID: 18575712
    [Abstract] [Full Text] [Related]

  • 12. Mutant V600E BRAF increases hypoxia inducible factor-1alpha expression in melanoma.
    Kumar SM, Yu H, Edwards R, Chen L, Kazianis S, Brafford P, Acs G, Herlyn M, Xu X.
    Cancer Res; 2007 Apr 01; 67(7):3177-84. PubMed ID: 17409425
    [Abstract] [Full Text] [Related]

  • 13. Mutation analysis of p53, K-ras, and BRAF genes in colorectal cancer progression.
    Calistri D, Rengucci C, Seymour I, Lattuneddu A, Polifemo AM, Monti F, Saragoni L, Amadori D.
    J Cell Physiol; 2005 Aug 01; 204(2):484-8. PubMed ID: 15702478
    [Abstract] [Full Text] [Related]

  • 14. Somatic BRAF-V600E mutations in familial colorectal cancer.
    Vandrovcova J, Lagerstedt-Robinsson K, Påhlman L, Lindblom A.
    Cancer Epidemiol Biomarkers Prev; 2006 Nov 01; 15(11):2270-3. PubMed ID: 17119056
    [Abstract] [Full Text] [Related]

  • 15. Colorectal cancer with mutation in BRAF, KRAS, and wild-type with respect to both oncogenes showing different patterns of DNA methylation.
    Nagasaka T, Sasamoto H, Notohara K, Cullings HM, Takeda M, Kimura K, Kambara T, MacPhee DG, Young J, Leggett BA, Jass JR, Tanaka N, Matsubara N.
    J Clin Oncol; 2004 Nov 15; 22(22):4584-94. PubMed ID: 15542810
    [Abstract] [Full Text] [Related]

  • 16. Concordance in KRAS and BRAF mutations in endoscopic biopsy samples and resection specimens of colorectal adenocarcinoma.
    Krol LC, 't Hart NA, Methorst N, Knol AJ, Prinsen C, Boers JE.
    Eur J Cancer; 2012 May 15; 48(7):1108-15. PubMed ID: 22446020
    [Abstract] [Full Text] [Related]

  • 17. Sorafenib inhibits non-small cell lung cancer cell growth by targeting B-RAF in KRAS wild-type cells and C-RAF in KRAS mutant cells.
    Takezawa K, Okamoto I, Yonesaka K, Hatashita E, Yamada Y, Fukuoka M, Nakagawa K.
    Cancer Res; 2009 Aug 15; 69(16):6515-21. PubMed ID: 19638574
    [Abstract] [Full Text] [Related]

  • 18. KRAS and BRAF oncogenic mutations in MSS colorectal carcinoma progression.
    Oliveira C, Velho S, Moutinho C, Ferreira A, Preto A, Domingo E, Capelinha AF, Duval A, Hamelin R, Machado JC, Schwartz S, Carneiro F, Seruca R.
    Oncogene; 2007 Jan 04; 26(1):158-63. PubMed ID: 16953233
    [Abstract] [Full Text] [Related]

  • 19. Alternative splicing of BRAF transcripts and characterization of C-terminally truncated B-Raf isoforms in colorectal cancer.
    Hirschi B, Kolligs FT.
    Int J Cancer; 2013 Aug 01; 133(3):590-6. PubMed ID: 23354951
    [Abstract] [Full Text] [Related]

  • 20. Mutation analysis of the BRAF, ARAF and RAF-1 genes in human colorectal adenocarcinomas.
    Fransén K, Klintenäs M, Osterström A, Dimberg J, Monstein HJ, Söderkvist P.
    Carcinogenesis; 2004 Apr 01; 25(4):527-33. PubMed ID: 14688025
    [Abstract] [Full Text] [Related]


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