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Journal Abstract Search

627 related items for PubMed ID: 18602963

  • 1. Short hairpin RNA targeted to dihydrofolate reductase enhances the immunoglobulin G expression in gene-amplified stable Chinese hamster ovary cells.
    Wu SC, Hong WW, Liu JH.
    Vaccine; 2008 Sep 08; 26(38):4969-74. PubMed ID: 18602963
    [Abstract] [Full Text] [Related]

  • 2. A novel RNA silencing vector to improve antigen expression and stability in Chinese hamster ovary cells.
    Hong WW, Wu SC.
    Vaccine; 2007 May 16; 25(20):4103-11. PubMed ID: 17428585
    [Abstract] [Full Text] [Related]

  • 3. Identification and analysis of specific chromosomal region adjacent to exogenous Dhfr-amplified region in Chinese hamster ovary cell genome.
    Park JY, Takagi Y, Yamatani M, Honda K, Asakawa S, Shimizu N, Omasa T, Ohtake H.
    J Biosci Bioeng; 2010 May 16; 109(5):504-11. PubMed ID: 20347775
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  • 4. A single-plasmid vector for transgene amplification using short hairpin RNA targeting the 3'-UTR of amplifiable dhfr.
    Kang SY, Kim YG, Lee HW, Lee EG.
    Appl Microbiol Biotechnol; 2015 Dec 16; 99(23):10117-26. PubMed ID: 26245680
    [Abstract] [Full Text] [Related]

  • 5. Clonal variability within dihydrofolate reductase-mediated gene amplified Chinese hamster ovary cells: stability in the absence of selective pressure.
    Kim NS, Kim SJ, Lee GM.
    Biotechnol Bioeng; 1998 Dec 20; 60(6):679-88. PubMed ID: 10099478
    [Abstract] [Full Text] [Related]

  • 6. [Significantly improvement of antibody expression level in CHO cells through downregulation of the DHFR gene in expression vector].
    Bai Y, Wang Y, Zhang HR, Zhou LJ, Lu YQ, Yu LZ.
    Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi; 2003 Jan 20; 19(1):62-4, 67. PubMed ID: 15132910
    [Abstract] [Full Text] [Related]

  • 7. Key determinants in the occurrence of clonal variation in humanized antibody expression of cho cells during dihydrofolate reductase mediated gene amplification.
    Kim NS, Byun TH, Lee GM.
    Biotechnol Prog; 2001 Jan 20; 17(1):69-75. PubMed ID: 11170482
    [Abstract] [Full Text] [Related]

  • 8. Co-expression and amplification of dihydrofolate reductase cDNA and the Escherichia coli XGPRT gene in Chinese hamster ovary cells.
    Ringold G, Dieckmann B, Lee F.
    J Mol Appl Genet; 1981 Jan 20; 1(3):165-75. PubMed ID: 6180118
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  • 9. Transfection of a nonactive site mutant murine DHFR cDNA (the tryptophan 15 mutant) into Chinese hamster ovary and mouse marrow progenitor cells imparts MTX resistance in vitro.
    Banerjee D, Zhao SC, Tong Y, Steinherz J, Gritsman K, Bertino JR.
    Cancer Gene Ther; 1994 Sep 20; 1(3):181-4. PubMed ID: 7621249
    [Abstract] [Full Text] [Related]

  • 10. Regulation of dihydrofolate reductase in human breast cancer cells and in mutant hamster cells transfected with a human dihydrofolate reductase minigene.
    Cowan KH, Goldsmith ME, Ricciardone MD, Levine R, Rubalcaba E, Jolivet J.
    Mol Pharmacol; 1986 Jul 20; 30(1):69-76. PubMed ID: 3724746
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  • 13. Amplification and expression of recombinant genes in serum-independent Chinese hamster ovary cells.
    Gandor C, Leist C, Fiechter A, Asselbergs FA.
    FEBS Lett; 1995 Dec 27; 377(3):290-4. PubMed ID: 8549740
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  • 14. [Expression of human-mouse chimeric antibody ch-BD1 and its affinity to human bladder cancer in vitro and in vivo].
    Bai Y, Yu LZ, Lü YQ, Ai JK, Zhou LJ, Zhang CL, Wang Y.
    Zhonghua Yi Xue Za Zhi; 2003 Feb 25; 83(4):333-7. PubMed ID: 12812655
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  • 17. Selection for methotrexate resistance in mammalian cells bearing a Drosophila dihydrofolate reductase transgene: Methotrexate resistance in transgenic mammalian cells.
    Affleck JG, Nowickyj SM, Walker VK.
    Cell Biol Toxicol; 2010 Apr 25; 26(2):117-26. PubMed ID: 19337845
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  • 18. Generation of high-expressing cells by methotrexate amplification of destabilized dihydrofolate reductase selection marker.
    Ng SK.
    Methods Mol Biol; 2012 Apr 25; 801():161-72. PubMed ID: 21987253
    [Abstract] [Full Text] [Related]

  • 19. A study of monoclonal antibody-producing CHO cell lines: what makes a stable high producer?
    Chusainow J, Yang YS, Yeo JH, Toh PC, Asvadi P, Wong NS, Yap MG.
    Biotechnol Bioeng; 2009 Mar 01; 102(4):1182-96. PubMed ID: 18979540
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