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Journal Abstract Search

366 related items for PubMed ID: 1860509

  • 1. [Blood plasma proteins and drug transport across the hemato-encephalic barrier].
    Lutsevich AN, Bender KI, Kupchikov VV.
    Farmakol Toksikol; 1991; 54(1):70-6. PubMed ID: 1860509
    [Abstract] [Full Text] [Related]

  • 2. [The blood-brain barrier and drug delivery in the central nervous system].
    Loch-Neckel G, Koepp J.
    Rev Neurol; 2010 Aug; 51(3):165-74. PubMed ID: 20645267
    [Abstract] [Full Text] [Related]

  • 3. Relationship between exposure and nonspecific binding of thirty-three central nervous system drugs in mice.
    Maurer TS, Debartolo DB, Tess DA, Scott DO.
    Drug Metab Dispos; 2005 Jan; 33(1):175-81. PubMed ID: 15502010
    [Abstract] [Full Text] [Related]

  • 4. [Neuropeptides and the hemato-encephalic barrier].
    Mar'ianovich AT, Poliakov EL.
    Usp Fiziol Nauk; 1991 Jan; 22(2):33-51. PubMed ID: 1853639
    [No Abstract] [Full Text] [Related]

  • 5. Effect of P-glycoprotein-mediated efflux on cerebrospinal fluid/plasma concentration ratio.
    Ohe T, Sato M, Tanaka S, Fujino N, Hata M, Shibata Y, Kanatani A, Fukami T, Yamazaki M, Chiba M, Ishii Y.
    Drug Metab Dispos; 2003 Oct; 31(10):1251-4. PubMed ID: 12975334
    [Abstract] [Full Text] [Related]

  • 6. Carrier-mediated delivery of metabotrophic glutamate receptor ligands to the central nervous system: structural tolerance and potential of the L-system amino acid transporter at the blood-brain barrier.
    Reichel A, Begley DJ, Abbott NJ.
    J Cereb Blood Flow Metab; 2000 Jan; 20(1):168-74. PubMed ID: 10616805
    [Abstract] [Full Text] [Related]

  • 7. Effect of P-glycoprotein-mediated efflux on cerebrospinal fluid concentrations in rhesus monkeys.
    Tang C, Kuo Y, Pudvah NT, Ellis JD, Michener MS, Egbertson M, Graham SL, Cook JJ, Hochman JH, Prueksaritanont T.
    Biochem Pharmacol; 2009 Sep 15; 78(6):642-7. PubMed ID: 19481060
    [Abstract] [Full Text] [Related]

  • 8. Strategies to optimize brain penetration in drug discovery.
    Liu X, Chen C.
    Curr Opin Drug Discov Devel; 2005 Jul 15; 8(4):505-12. PubMed ID: 16022187
    [Abstract] [Full Text] [Related]

  • 9. [The blood-brain barrier. II. Physiological data (conclusion)].
    Lefauconnier JM, Hauw JJ.
    Rev Neurol (Paris); 1984 Jul 15; 140(2):89-109. PubMed ID: 6143382
    [Abstract] [Full Text] [Related]

  • 10. Active-site concentrations of chemicals - are they a better predictor of effect than plasma/organ/tissue concentrations?
    Hammarlund-Udenaes M.
    Basic Clin Pharmacol Toxicol; 2010 Mar 15; 106(3):215-20. PubMed ID: 20050843
    [Abstract] [Full Text] [Related]

  • 11. Effect of plasma protein binding on in vivo activity and brain penetration of glycine/NMDA receptor antagonists.
    Rowley M, Kulagowski JJ, Watt AP, Rathbone D, Stevenson GI, Carling RW, Baker R, Marshall GR, Kemp JA, Foster AC, Grimwood S, Hargreaves R, Hurley C, Saywell KL, Tricklebank MD, Leeson PD.
    J Med Chem; 1997 Dec 05; 40(25):4053-68. PubMed ID: 9406596
    [Abstract] [Full Text] [Related]

  • 12. Principles and applicability of CSF sampling for the assessment of CNS drug delivery and pharmacodynamics.
    Shen DD, Artru AA, Adkison KK.
    Adv Drug Deliv Rev; 2004 Oct 14; 56(12):1825-57. PubMed ID: 15381336
    [Abstract] [Full Text] [Related]

  • 13. Epilepsy and the blood-brain barrier.
    Cornford EM, Oldendorf WH.
    Adv Neurol; 1986 Oct 14; 44():787-812. PubMed ID: 3085437
    [Abstract] [Full Text] [Related]

  • 14. [Biological bases of the regulation of the age-related pharmacokinetics of neurotropic agents in the brain].
    Fateev VA, Titov NS, Saliaev VN.
    Farmakol Toksikol; 1984 Oct 14; 47(2):80-5. PubMed ID: 6325232
    [No Abstract] [Full Text] [Related]

  • 15. Blood-brain barrier transport helps to explain discrepancies in in vivo potency between oxycodone and morphine.
    Boström E, Hammarlund-Udenaes M, Simonsson US.
    Anesthesiology; 2008 Mar 14; 108(3):495-505. PubMed ID: 18292687
    [Abstract] [Full Text] [Related]

  • 16. Effect of the binding of isradipine and darodipine to different plasma proteins on their transfer through the rat blood-brain barrier. Drug binding to lipoproteins does not limit the transfer of drug.
    Urien S, Pinquier JL, Paquette B, Chaumet-Riffaud P, Kiechel JR, Tillement JP.
    J Pharmacol Exp Ther; 1987 Jul 14; 242(1):349-53. PubMed ID: 2956411
    [Abstract] [Full Text] [Related]

  • 17. Addressing central nervous system (CNS) penetration in drug discovery: basics and implications of the evolving new concept.
    Reichel A.
    Chem Biodivers; 2009 Nov 14; 6(11):2030-49. PubMed ID: 19937839
    [Abstract] [Full Text] [Related]

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