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258 related items for PubMed ID: 18607581

  • 1. Genetic determinants of methotrexate toxicity in rheumatoid arthritis patients: a study of polymorphisms affecting methotrexate transport and folate metabolism.
    Bohanec Grabar P, Logar D, Lestan B, Dolzan V.
    Eur J Clin Pharmacol; 2008 Nov; 64(11):1057-68. PubMed ID: 18607581
    [Abstract] [Full Text] [Related]

  • 2. Genetic Determinants of Methotrexate Toxicity in Tunisian Patients with Rheumatoid Arthritis: A Study of Polymorphisms Involved in the MTX Metabolic Pathway.
    Chaabane S, Marzouk S, Akrout R, Ben Hamad M, Achour Y, Rebai A, Keskes L, Fourati H, Bahloul Z, Maalej A.
    Eur J Drug Metab Pharmacokinet; 2016 Aug; 41(4):385-93. PubMed ID: 26077125
    [Abstract] [Full Text] [Related]

  • 3. Association of hyperhomocysteinemia with genetic variants in key enzymes of homocysteine metabolism and methotrexate toxicity in rheumatoid arthritis patients.
    Chaabane S, Messedi M, Akrout R, Ben Hamad M, Turki M, Marzouk S, Keskes L, Bahloul Z, Rebai A, Ayedi F, Maalej A.
    Inflamm Res; 2018 Aug; 67(8):703-710. PubMed ID: 29796841
    [Abstract] [Full Text] [Related]

  • 4. Methotrexate (MTX) pathway gene polymorphisms and their effects on MTX toxicity in Caucasian and African American patients with rheumatoid arthritis.
    Ranganathan P, Culverhouse R, Marsh S, Mody A, Scott-Horton TJ, Brasington R, Joseph A, Reddy V, Eisen S, McLeod HL.
    J Rheumatol; 2008 Apr; 35(4):572-9. PubMed ID: 18381794
    [Abstract] [Full Text] [Related]

  • 5. Pharmacogenetic polymorphisms contributing to toxicity induced by methotrexate in the southern Spanish population with rheumatoid arthritis.
    Plaza-Plaza JC, Aguilera M, Cañadas-Garre M, Chemello C, González-Utrilla A, Faus Dader MJ, Calleja MA.
    OMICS; 2012 Nov; 16(11):589-95. PubMed ID: 23095111
    [Abstract] [Full Text] [Related]

  • 6. Gene polymorphisms involved in folate and methionine metabolism and increased risk of sporadic colorectal adenocarcinoma.
    Guimarães JL, Ayrizono Mde L, Coy CS, Lima CS.
    Tumour Biol; 2011 Oct; 32(5):853-61. PubMed ID: 21603981
    [Abstract] [Full Text] [Related]

  • 7. MTRR A66G, RFC1 G80A, and MTHFR C677T and A1298C Polymorphisms and Disease Activity in Mexicans with Rheumatoid Arthritis Treated with Methotrexate.
    González-Mercado MG, Rivas F, Gallegos-Arreola MP, Morán-Moguel MC, Salazar-Páramo M, González-López L, Gámez-Nava JI, Muñoz-Valle JF, Medina-Coss Y León R, González-Mercado A, Aceves MA, Dávalos NO, Macías-Chumacera A, Dávalos IP.
    Genet Test Mol Biomarkers; 2017 Nov; 21(11):698-704. PubMed ID: 28994615
    [Abstract] [Full Text] [Related]

  • 8. Polymorphisms of methylenetetrahydrofolate reductase (MTHFR), methionine synthase (MTR), methionine synthase reductase (MTRR), and thymidylate synthase (TYMS) in multiple myeloma risk.
    Lima CS, Ortega MM, Ozelo MC, Araujo RC, De Souza CA, Lorand-Metze I, Annichino-Bizzacchi JM, Costa FF.
    Leuk Res; 2008 Mar; 32(3):401-5. PubMed ID: 17655928
    [Abstract] [Full Text] [Related]

  • 9. Expression of methotrexate transporters and metabolizing enzymes in rheumatoid synovial tissue.
    Stamp LK, Hazlett J, Highton J, Hessian PA.
    J Rheumatol; 2013 Sep; 40(9):1519-22. PubMed ID: 23858048
    [Abstract] [Full Text] [Related]

  • 10. Polymorphisms in the thymidylate synthase and methylenetetrahydrofolate reductase genes and sensitivity to the low-dose methotrexate therapy in patients with rheumatoid arthritis.
    Kumagai K, Hiyama K, Oyama T, Maeda H, Kohno N.
    Int J Mol Med; 2003 May; 11(5):593-600. PubMed ID: 12684695
    [Abstract] [Full Text] [Related]

  • 11. Association of genetic polymorphism in the folate metabolic pathway with methotrexate pharmacokinetics and toxicity in childhood acute lymphoblastic leukaemia and malignant lymphoma.
    Faganel Kotnik B, Grabnar I, Bohanec Grabar P, Dolžan V, Jazbec J.
    Eur J Clin Pharmacol; 2011 Oct; 67(10):993-1006. PubMed ID: 21509569
    [Abstract] [Full Text] [Related]

  • 12. Joint associations of folate, homocysteine and MTHFR, MTR and MTRR gene polymorphisms with dyslipidemia in a Chinese hypertensive population: a cross-sectional study.
    Li WX, Lv WW, Dai SX, Pan ML, Huang JF.
    Lipids Health Dis; 2015 Sep 04; 14():101. PubMed ID: 26337056
    [Abstract] [Full Text] [Related]

  • 13. Association of MTHFR, MTR, MTRR, RFC1, and DHFR gene polymorphisms with susceptibility to sporadic colon cancer.
    Jokić M, Brčić-Kostić K, Stefulj J, Catela Ivković T, Božo L, Gamulin M, Kapitanović S.
    DNA Cell Biol; 2011 Oct 04; 30(10):771-6. PubMed ID: 21438757
    [Abstract] [Full Text] [Related]

  • 14. Thymidylate synthase genetic polymorphism and plasma total homocysteine level in a group of Turkish patients with rheumatoid arthritis: relationship with disease activity and methotrexate toxicity.
    Borman P, Taşbaş Ö, Karabulut H, Tukun A, Yorgancıoğlu R.
    Rev Bras Reumatol; 2015 Oct 04; 55(6):485-92. PubMed ID: 25687398
    [Abstract] [Full Text] [Related]

  • 15. [Case-control study on the association between four single nucleotide polymorphisms in folate metabolism way and the risk of congenital heart disease].
    Duan S, Li G, Qiu F, Zhao L, Zhao M, Wang L, Feng Z, Ma X.
    Wei Sheng Yan Jiu; 2018 Jul 04; 47(4):536-542. PubMed ID: 30081977
    [Abstract] [Full Text] [Related]

  • 16. Associations between single-nucleotide polymorphisms of RFC-1, GGH, MTHFR , TYMS, and TCII genes and the efficacy and toxicity of methotrexate treatment in patients with rheumatoid arthritis.
    Świerkot J, Ślęzak R, Karpiński P, Pawłowska J, Noga L, Szechiński J, Wiland P.
    Pol Arch Med Wewn; 2015 Jul 04; 125(3):152-61. PubMed ID: 25599563
    [Abstract] [Full Text] [Related]

  • 17. Polymorphisms and pharmacogenomics for the toxicity of methotrexate monotherapy in patients with rheumatoid arthritis: A systematic review and meta-analysis.
    Qiu Q, Huang J, Lin Y, Shu X, Fan H, Tu Z, Zhou Y, Xiao C.
    Medicine (Baltimore); 2017 Mar 04; 96(11):e6337. PubMed ID: 28296761
    [Abstract] [Full Text] [Related]

  • 18. An Association Study Between Gene Polymorphisms of Folic Acid Metabolism Enzymes and Biochemical and Hormonal Parameters in Acromegaly.
    Tetik Vardarlı A, Zengi A, Bozok Çetintaş V, Karadeniz M, Tamsel S, Küçükaslan AŞ, Köse T, Saygılı F, Eroglu Z.
    Genet Test Mol Biomarkers; 2015 Aug 04; 19(8):431-8. PubMed ID: 26154858
    [Abstract] [Full Text] [Related]

  • 19. Polymorphisms in folate-related genes and risk of pediatric acute lymphoblastic leukemia.
    de Jonge R, Tissing WJ, Hooijberg JH, Jansen G, Kaspers GJ, Lindemans J, Peters GJ, Pieters R.
    Blood; 2009 Mar 05; 113(10):2284-9. PubMed ID: 19020309
    [Abstract] [Full Text] [Related]

  • 20. Genetic polymorphisms in metabolic and cellular transport pathway of methotrexate impact clinical outcome of methotrexate monotherapy in Japanese patients with rheumatoid arthritis.
    Kato T, Hamada A, Mori S, Saito H.
    Drug Metab Pharmacokinet; 2012 Mar 05; 27(2):192-9. PubMed ID: 22104130
    [Abstract] [Full Text] [Related]

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