These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Journal Abstract Search

214 related items for PubMed ID: 18614532

  • 1. Multiple cyclin kinase inhibitors promote bile acid-induced apoptosis and autophagy in primary hepatocytes via p53-CD95-dependent signaling.
    Zhang G, Park MA, Mitchell C, Walker T, Hamed H, Studer E, Graf M, Rahmani M, Gupta S, Hylemon PB, Fisher PB, Grant S, Dent P.
    J Biol Chem; 2008 Sep 05; 283(36):24343-58. PubMed ID: 18614532
    [Abstract] [Full Text] [Related]

  • 2. Regulation of autophagy by ceramide-CD95-PERK signaling.
    Park MA, Zhang G, Norris J, Hylemon PB, Fisher PB, Grant S, Dent P.
    Autophagy; 2008 Oct 05; 4(7):929-31. PubMed ID: 18719356
    [Abstract] [Full Text] [Related]

  • 3. Cyclin kinase inhibitor p21 potentiates bile acid-induced apoptosis in hepatocytes that is dependent on p53.
    Qiao L, McKinstry R, Gupta S, Gilfor D, Windle JJ, Hylemon PB, Grant S, Fisher PB, Dent P.
    Hepatology; 2002 Jul 05; 36(1):39-48. PubMed ID: 12085347
    [Abstract] [Full Text] [Related]

  • 4. Deoxycholic acid (DCA) causes ligand-independent activation of epidermal growth factor receptor (EGFR) and FAS receptor in primary hepatocytes: inhibition of EGFR/mitogen-activated protein kinase-signaling module enhances DCA-induced apoptosis.
    Qiao L, Studer E, Leach K, McKinstry R, Gupta S, Decker R, Kukreja R, Valerie K, Nagarkatti P, El Deiry W, Molkentin J, Schmidt-Ullrich R, Fisher PB, Grant S, Hylemon PB, Dent P.
    Mol Biol Cell; 2001 Sep 05; 12(9):2629-45. PubMed ID: 11553704
    [Abstract] [Full Text] [Related]

  • 5. Cisplatin enhances protein kinase R-like endoplasmic reticulum kinase- and CD95-dependent melanoma differentiation-associated gene-7/interleukin-24-induced killing in ovarian carcinoma cells.
    Yacoub A, Liu R, Park MA, Hamed HA, Dash R, Schramm DN, Sarkar D, Dimitriev IP, Bell JK, Grant S, Farrell NP, Curiel DT, Fisher PB, Dent P.
    Mol Pharmacol; 2010 Feb 05; 77(2):298-310. PubMed ID: 19910452
    [Abstract] [Full Text] [Related]

  • 6. Inhibition of the MAPK and PI3K pathways enhances UDCA-induced apoptosis in primary rodent hepatocytes.
    Qiao L, Yacoub A, Studer E, Gupta S, Pei XY, Grant S, Hylemon PB, Dent P.
    Hepatology; 2002 Apr 05; 35(4):779-89. PubMed ID: 11915023
    [Abstract] [Full Text] [Related]

  • 7. Bile acid regulation of C/EBPbeta, CREB, and c-Jun function, via the extracellular signal-regulated kinase and c-Jun NH2-terminal kinase pathways, modulates the apoptotic response of hepatocytes.
    Qiao L, Han SI, Fang Y, Park JS, Gupta S, Gilfor D, Amorino G, Valerie K, Sealy L, Engelhardt JF, Grant S, Hylemon PB, Dent P.
    Mol Cell Biol; 2003 May 05; 23(9):3052-66. PubMed ID: 12697808
    [Abstract] [Full Text] [Related]

  • 8. 17-allylamino-17-demethoxygeldanamycin and MEK1/2 inhibitors kill GI tumor cells via Ca2+-dependent suppression of GRP78/BiP and induction of ceramide and reactive oxygen species.
    Walker T, Mitchell C, Park MA, Yacoub A, Rahmani M, Häussinger D, Reinehr R, Voelkel-Johnson C, Fisher PB, Grant S, Dent P.
    Mol Cancer Ther; 2010 May 05; 9(5):1378-95. PubMed ID: 20442308
    [Abstract] [Full Text] [Related]

  • 9. MDA-7/IL-24-induced cell killing in malignant renal carcinoma cells occurs by a ceramide/CD95/PERK-dependent mechanism.
    Park MA, Walker T, Martin AP, Allegood J, Vozhilla N, Emdad L, Sarkar D, Rahmani M, Graf M, Yacoub A, Koumenis C, Spiegel S, Curiel DT, Voelkel-Johnson C, Grant S, Fisher PB, Dent P.
    Mol Cancer Ther; 2009 May 05; 8(5):1280-91. PubMed ID: 19417161
    [Abstract] [Full Text] [Related]

  • 10. 17-Allylamino-17-demethoxygeldanamycin enhances the lethality of deoxycholic acid in primary rodent hepatocytes and established cell lines.
    Mitchell C, Park MA, Zhang G, Han SI, Harada H, Franklin RA, Yacoub A, Li PL, Hylemon PB, Grant S, Dent P.
    Mol Cancer Ther; 2007 Feb 05; 6(2):618-32. PubMed ID: 17308059
    [Abstract] [Full Text] [Related]

  • 11. Deoxycholic acid activates the c-Jun N-terminal kinase pathway via FAS receptor activation in primary hepatocytes. Role of acidic sphingomyelinase-mediated ceramide generation in FAS receptor activation.
    Gupta S, Natarajan R, Payne SG, Studer EJ, Spiegel S, Dent P, Hylemon PB.
    J Biol Chem; 2004 Feb 13; 279(7):5821-8. PubMed ID: 14660582
    [Abstract] [Full Text] [Related]

  • 12. Vorinostat and sorafenib increase ER stress, autophagy and apoptosis via ceramide-dependent CD95 and PERK activation.
    Park MA, Zhang G, Martin AP, Hamed H, Mitchell C, Hylemon PB, Graf M, Rahmani M, Ryan K, Liu X, Spiegel S, Norris J, Fisher PB, Grant S, Dent P.
    Cancer Biol Ther; 2008 Oct 13; 7(10):1648-62. PubMed ID: 18787411
    [Abstract] [Full Text] [Related]

  • 13. p53 is a key molecular target of ursodeoxycholic acid in regulating apoptosis.
    Amaral JD, Castro RE, Solá S, Steer CJ, Rodrigues CM.
    J Biol Chem; 2007 Nov 23; 282(47):34250-9. PubMed ID: 17881359
    [Abstract] [Full Text] [Related]

  • 14. Hepatitis B virus X protein increases expression of p21(Cip-1/WAF1/MDA6) and p27(Kip-1) in primary mouse hepatocytes, leading to reduced cell cycle progression.
    Qiao L, Leach K, McKinstry R, Gilfor D, Yacoub A, Park JS, Grant S, Hylemon PB, Fisher PB, Dent P.
    Hepatology; 2001 Nov 23; 34(5):906-17. PubMed ID: 11679961
    [Abstract] [Full Text] [Related]

  • 15. Autophagy induced by deficiency of sphingosine-1-phosphate phosphohydrolase 1 is switched to apoptosis by calpain-mediated autophagy-related gene 5 (Atg5) cleavage.
    Lépine S, Allegood JC, Edmonds Y, Milstien S, Spiegel S.
    J Biol Chem; 2011 Dec 30; 286(52):44380-90. PubMed ID: 22052905
    [Abstract] [Full Text] [Related]

  • 16. p53 efficiently suppresses tumor development in the complete absence of its cell-cycle inhibitory and proapoptotic effectors p21, Puma, and Noxa.
    Valente LJ, Gray DH, Michalak EM, Pinon-Hofbauer J, Egle A, Scott CL, Janic A, Strasser A.
    Cell Rep; 2013 May 30; 3(5):1339-45. PubMed ID: 23665218
    [Abstract] [Full Text] [Related]

  • 17. c-Jun N-terminal kinase 1/c-Jun activation of the p53/microRNA 34a/sirtuin 1 pathway contributes to apoptosis induced by deoxycholic acid in rat liver.
    Ferreira DM, Afonso MB, Rodrigues PM, Simão AL, Pereira DM, Borralho PM, Rodrigues CM, Castro RE.
    Mol Cell Biol; 2014 Mar 30; 34(6):1100-20. PubMed ID: 24421392
    [Abstract] [Full Text] [Related]

  • 18. Autophagy blockade sensitizes the anticancer activity of CA-4 via JNK-Bcl-2 pathway.
    Li Y, Luo P, Wang J, Dai J, Yang X, Wu H, Yang B, He Q.
    Toxicol Appl Pharmacol; 2014 Jan 15; 274(2):319-27. PubMed ID: 24321340
    [Abstract] [Full Text] [Related]

  • 19. p53 mediates mitochondria dysfunction-triggered autophagy activation and cell death in rat striatum.
    Zhang XD, Wang Y, Wang Y, Zhang X, Han R, Wu JC, Liang ZQ, Gu ZL, Han F, Fukunaga K, Qin ZH.
    Autophagy; 2009 Apr 15; 5(3):339-50. PubMed ID: 19305162
    [Abstract] [Full Text] [Related]

  • 20. Differential regulation of cyclin D1 and cell death by bile acids in primary rat hepatocytes.
    Castro RE, Amaral JD, Solá S, Kren BT, Steer CJ, Rodrigues CM.
    Am J Physiol Gastrointest Liver Physiol; 2007 Jul 15; 293(1):G327-34. PubMed ID: 17431217
    [Abstract] [Full Text] [Related]

    Page: [Next] [New Search]
    of 11.