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427 related items for PubMed ID: 18620055
1. Synthesis, biochemical evaluation and rationalisation of the inhibitory activity of a range of phenyl alkyl imidazole-based compounds as potent inhibitors of the enzyme complex 17alpha-hydroxylase/17,20-lyase (P450(17alpha)). Owen CP, Shahid I, Olusanjo MS, Patel CH, Dhanani S, Ahmed S. J Steroid Biochem Mol Biol; 2008 Jul; 111(1-2):117-27. PubMed ID: 18620055 [Abstract] [Full Text] [Related]
2. Synthesis, biochemical evaluation of a range of potent 4-substituted phenyl alkyl imidazole-based inhibitors of the enzyme complex 17alpha-Hydroxylase/17,20-Lyase (P45017alpha). Shahid I, Patel CH, Dhanani S, Owen CP, Ahmed S. J Steroid Biochem Mol Biol; 2008 May; 110(1-2):18-29. PubMed ID: 18407491 [Abstract] [Full Text] [Related]
3. Synthesis and biochemical evaluation of a range of potent benzyl imidazole-based compounds as potential inhibitors of the enzyme complex 17alpha-hydroxylase/17,20-lyase (P450(17alpha)). Owen CP, Dhanani S, Patel CH, Shahid I, Ahmed S. Bioorg Med Chem Lett; 2006 Aug 01; 16(15):4011-5. PubMed ID: 16750362 [Abstract] [Full Text] [Related]
5. Synthesis, biochemical evaluation and rationalisation of the inhibitory activity of a range of 4-hydroxyphenyl ketones as potent and specific inhibitors of the type 3 of 17beta-hydroxysteroid dehydrogenase (17beta-HSD3). Lota RK, Olusanjo MS, Dhanani S, Owen CP, Ahmed S. J Steroid Biochem Mol Biol; 2008 Jul 01; 111(1-2):128-37. PubMed ID: 18620056 [Abstract] [Full Text] [Related]
6. Synthesis and biochemical evaluation of a range of (4-substituted phenyl)sulfonate derivatives of 4-hydroxybenzyl imidazole-based compounds as potent inhibitors of 17alpha-hydroxylase/17,20-lyase (P45017alpha) derived from rat testicular microsomes. Owen CP, Shahid I, Lee WY, Ahmed S. Bioorg Med Chem Lett; 2010 Sep 01; 20(17):5345-8. PubMed ID: 20675132 [Abstract] [Full Text] [Related]
7. Synthesis and biochemical evaluation of a range of sulfonated derivatives of 4-hydroxybenzyl imidazole as highly potent inhibitors of rat testicular 17alpha-hydroxylase/17,20-lyase (P-450(17alpha)). Ahmed S, Shahid I, Dhanani S, Owen CP. Bioorg Med Chem Lett; 2009 Aug 15; 19(16):4698-701. PubMed ID: 19608417 [Abstract] [Full Text] [Related]
8. Synthesis, biochemical evaluation and rationalisation of the inhibitory activity of a series of 4-hydroxyphenyl ketones as potential inhibitors of 17beta-hydroxysteroid dehydrogenase type 3 (17beta-HSD3). Lota RK, Dhanani S, Owen CP, Ahmed S. Bioorg Med Chem Lett; 2006 Sep 01; 16(17):4519-22. PubMed ID: 16797984 [Abstract] [Full Text] [Related]
9. Synthesis and evaluation of 17-aliphatic heterocycle-substituted steroidal inhibitors of 17alpha-hydroxylase/C17-20-lyase (P450 17). Hartmann RW, Hector M, Wachall BG, Palusczak A, Palzer M, Huch V, Veith M. J Med Chem; 2000 Nov 16; 43(23):4437-45. PubMed ID: 11087568 [Abstract] [Full Text] [Related]
10. Altered expression of 3β-HSD, CYP17 and 17β-HSD in the foetal porcine gonads in response to anti-androgen flutamide exposure. Knapczyk-Stwora K, Grzesiak M, Slomczynska M. Reprod Domest Anim; 2014 Oct 16; 49(5):725-33. PubMed ID: 25130044 [Abstract] [Full Text] [Related]
11. Synthesis and biological evaluation of imidazole based compounds as cytochrome P-450 inhibitors. Ahmed S, Smith JH, Nicholls PJ, Whomsley R, Cariuk P. Drug Des Discov; 1995 Aug 16; 13(1):27-41. PubMed ID: 8882899 [Abstract] [Full Text] [Related]
12. Effects of genistein and equol on human and rat testicular 3beta-hydroxysteroid dehydrogenase and 17beta-hydroxysteroid dehydrogenase 3 activities. Hu GX, Zhao BH, Chu YH, Zhou HY, Akingbemi BT, Zheng ZQ, Ge RS. Asian J Androl; 2010 Jul 16; 12(4):519-26. PubMed ID: 20453869 [Abstract] [Full Text] [Related]
13. A novel molecular modelling study of inhibitors of the 17alpha-hydroxylase component of the enzyme system 17alpha-hydroxylase/17,20-lyase (P-450(17alpha)). Ahmed S. Bioorg Med Chem; 1999 Aug 16; 7(8):1487-96. PubMed ID: 10482440 [Abstract] [Full Text] [Related]
14. Inhibition of human and rat testicular steroidogenic enzyme activities by bisphenol A. Ye L, Zhao B, Hu G, Chu Y, Ge RS. Toxicol Lett; 2011 Nov 30; 207(2):137-42. PubMed ID: 21925253 [Abstract] [Full Text] [Related]
15. Triphenyltin and Tributyltin inhibit pig testicular 17beta-hydroxysteroid dehydrogenase activity and suppress testicular testosterone biosynthesis. Ohno S, Nakajima Y, Nakajin S. Steroids; 2005 Aug 30; 70(9):645-51. PubMed ID: 15899506 [Abstract] [Full Text] [Related]
16. Inhibition of testicular 17 alpha-hydroxylase and 17,20-lyase but not 3 beta-hydroxysteroid dehydrogenase-isomerase or 17 beta-hydroxysteroid oxidoreductase by ketoconazole and other imidazole drugs. Ayub M, Levell MJ. J Steroid Biochem; 1987 Nov 30; 28(5):521-31. PubMed ID: 2824931 [Abstract] [Full Text] [Related]
17. Inhibition of human and rat 3beta-hydroxysteroid dehydrogenase and 17beta-hydroxysteroid dehydrogenase 3 activities by perfluoroalkylated substances. Zhao B, Hu GX, Chu Y, Jin X, Gong S, Akingbemi BT, Zhang Z, Zirkin BR, Ge RS. Chem Biol Interact; 2010 Oct 06; 188(1):38-43. PubMed ID: 20619251 [Abstract] [Full Text] [Related]
18. Effects of novel 17alpha-hydroxylase/C17, 20-lyase (P450 17, CYP 17) inhibitors on androgen biosynthesis in vitro and in vivo. Haidar S, Ehmer PB, Barassin S, Batzl-Hartmann C, Hartmann RW. J Steroid Biochem Mol Biol; 2003 Apr 06; 84(5):555-62. PubMed ID: 12767280 [Abstract] [Full Text] [Related]
19. Imidazole substituted biphenyls: a new class of highly potent and in vivo active inhibitors of P450 17 as potential therapeutics for treatment of prostate cancer. Wachall BG, Hector M, Zhuang Y, Hartmann RW. Bioorg Med Chem; 1999 Sep 06; 7(9):1913-24. PubMed ID: 10530940 [Abstract] [Full Text] [Related]
20. Development of hormone-dependent prostate cancer models for the evaluation of inhibitors of 17beta-hydroxysteroid dehydrogenase type 3. Day JM, Tutill HJ, Foster PA, Bailey HV, Heaton WB, Sharland CM, Vicker N, Potter BV, Purohit A, Reed MJ. Mol Cell Endocrinol; 2009 Mar 25; 301(1-2):251-8. PubMed ID: 18786604 [Abstract] [Full Text] [Related] Page: [Next] [New Search]