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Journal Abstract Search

222 related items for PubMed ID: 18621522

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  • 3. Studies of the metabolic stability in cells of 5-(trifluoroacetyl)thiophene-2-carboxamides and identification of more stable class II histone deacetylase (HDAC) inhibitors.
    Scarpelli R, Di Marco A, Ferrigno F, Laufer R, Marcucci I, Muraglia E, Ontoria JM, Rowley M, Serafini S, Steinkühler C, Jones P.
    Bioorg Med Chem Lett; 2008 Dec 01; 18(23):6078-82. PubMed ID: 18952417
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  • 4. 3D QSAR models built on structure-based alignments of Abl tyrosine kinase inhibitors.
    Falchi F, Manetti F, Carraro F, Naldini A, Maga G, Crespan E, Schenone S, Bruno O, Brullo C, Botta M.
    ChemMedChem; 2009 Jun 01; 4(6):976-87. PubMed ID: 19326384
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  • 6. Discovery and SAR of 1,3,4-thiadiazole derivatives as potent Abl tyrosine kinase inhibitors and cytodifferentiating agents.
    Radi M, Crespan E, Botta G, Falchi F, Maga G, Manetti F, Corradi V, Mancini M, Santucci MA, Schenone S, Botta M.
    Bioorg Med Chem Lett; 2008 Feb 01; 18(3):1207-11. PubMed ID: 18078752
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  • 7. Two biologically active thiophene-3-carboxamide derivatives.
    Vasu, Nirmala KA, Chopra D, Mohan S, Saravanan J.
    Acta Crystallogr C; 2004 Sep 01; 60(Pt 9):o636-8. PubMed ID: 15345841
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  • 8. Abl inhibitor BMS354825 binding mode in Abelson kinase revealed by molecular docking studies.
    Gambacorti-Passerini C, Gasser M, Ahmed S, Assouline S, Scapozza L.
    Leukemia; 2005 Jul 01; 19(7):1267-9. PubMed ID: 15858616
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  • 9. Design and synthesis of N-(3,3-diphenylpropenyl)alkanamides as a novel class of high-affinity MT2-selective melatonin receptor ligands.
    Bedini A, Spadoni G, Gatti G, Lucarini S, Tarzia G, Rivara S, Lorenzi S, Lodola A, Mor M, Lucini V, Pannacci M, Scaglione F.
    J Med Chem; 2006 Dec 14; 49(25):7393-403. PubMed ID: 17149869
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  • 11. Design and synthesis of disubstituted thiophene and thiazole based inhibitors of JNK.
    Hom RK, Bowers S, Sealy JM, Truong AP, Probst GD, Neitzel ML, Neitz RJ, Fang L, Brogley L, Wu J, Konradi AW, Sham HL, Tóth G, Pan H, Yao N, Artis DR, Quinn K, Sauer JM, Powell K, Ren Z, Bard F, Yednock TA, Griswold-Prenner I.
    Bioorg Med Chem Lett; 2010 Dec 15; 20(24):7303-7. PubMed ID: 21071223
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  • 12. Design, synthesis, and biological evaluation of new 1,8-naphthyridin-4(1H)-on-3-carboxamide and quinolin-4(1H)-on-3-carboxamide derivatives as CB2 selective agonists.
    Manera C, Benetti V, Castelli MP, Cavallini T, Lazzarotti S, Pibiri F, Saccomanni G, Tuccinardi T, Vannacci A, Martinelli A, Ferrarini PL.
    J Med Chem; 2006 Oct 05; 49(20):5947-57. PubMed ID: 17004710
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  • 13. Design, synthesis, and structure-activity relationship of novel thiophene derivatives for beta-amyloid plaque imaging.
    Chandra R, Kung MP, Kung HF.
    Bioorg Med Chem Lett; 2006 Mar 01; 16(5):1350-2. PubMed ID: 16325402
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  • 14. Isomeric thiazole derivatives as ligands for the neuropeptide Y5 receptor.
    Nettekoven M, Guba W, Neidhart W, Mattei P, Pflieger P, Roche O, Taylor S.
    Bioorg Med Chem Lett; 2005 Jul 15; 15(14):3446-9. PubMed ID: 15951170
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  • 15. Virtual screening of Abl inhibitors from large compound libraries by support vector machines.
    Liu XH, Ma XH, Tan CY, Jiang YY, Go ML, Low BC, Chen YZ.
    J Chem Inf Model; 2009 Sep 15; 49(9):2101-10. PubMed ID: 19689138
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  • 16. 2-Aminothiophene-3-carboxylates and carboxamides as adenosine A1 receptor allosteric enhancers.
    Nikolakopoulos G, Figler H, Linden J, Scammells PJ.
    Bioorg Med Chem; 2006 Apr 01; 14(7):2358-65. PubMed ID: 16314104
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  • 17. Discovery of the novel antithrombotic agent 5-chloro-N-({(5S)-2-oxo-3- [4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)thiophene- 2-carboxamide (BAY 59-7939): an oral, direct factor Xa inhibitor.
    Roehrig S, Straub A, Pohlmann J, Lampe T, Pernerstorfer J, Schlemmer KH, Reinemer P, Perzborn E.
    J Med Chem; 2005 Sep 22; 48(19):5900-8. PubMed ID: 16161994
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  • 18. FK506-binding protein ligands: structure-based design, synthesis, and neurotrophic/neuroprotective properties of substituted 5,5-dimethyl-2-(4-thiazolidine)carboxylates.
    Zhao L, Huang W, Liu H, Wang L, Zhong W, Xiao J, Hu Y, Li S.
    J Med Chem; 2006 Jul 13; 49(14):4059-71. PubMed ID: 16821768
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  • 19. Structure-based design and subsequent optimization of 2-tolyl-(1,2,3-triazol-1-yl-4-carboxamide) inhibitors of p38 MAP kinase.
    Cogan DA, Aungst R, Breinlinger EC, Fadra T, Goldberg DR, Hao MH, Kroe R, Moss N, Pargellis C, Qian KC, Swinamer AD.
    Bioorg Med Chem Lett; 2008 Jun 01; 18(11):3251-5. PubMed ID: 18462940
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  • 20. A virtual screening approach for thymidine monophosphate kinase inhibitors as antitubercular agents based on docking and pharmacophore models.
    Gopalakrishnan B, Aparna V, Jeevan J, Ravi M, Desiraju GR.
    J Chem Inf Model; 2005 Jun 01; 45(4):1101-8. PubMed ID: 16045305
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