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146 related items for PubMed ID: 1862659

  • 1.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 2. Liver slices in dynamic organ culture. I. An alternative in vitro technique for the study of rat hepatic drug metabolism.
    Barr J, Weir AJ, Brendel K, Sipes IG.
    Xenobiotica; 1991 Mar; 21(3):331-9. PubMed ID: 1862658
    [Abstract] [Full Text] [Related]

  • 3. Comparison of the metabolism of 7-ethoxycoumarin and coumarin in precision-cut rat liver and lung slices.
    Price RJ, Renwick AB, Beamand JA, Esclangon F, Wield PT, Walters DG, Lake BG.
    Food Chem Toxicol; 1995 Mar; 33(3):233-7. PubMed ID: 7896234
    [Abstract] [Full Text] [Related]

  • 4. Structural and functional integrity of precision-cut liver slices in xenobiotic metabolism: a comparison of the dynamic organ and multiwell plate culture procedures.
    Hashemi E, Dobrota M, Till C, Ioannides C.
    Xenobiotica; 1999 Jan; 29(1):11-25. PubMed ID: 10078837
    [Abstract] [Full Text] [Related]

  • 5. Metabolism of coumarin and 7-ethoxycoumarin by rat, mouse, guinea pig, cynomolgus monkey and human precision-cut liver slices.
    Steensma A, Beamand JA, Walters DG, Price RJ, Lake BG.
    Xenobiotica; 1994 Sep; 24(9):893-907. PubMed ID: 7810171
    [Abstract] [Full Text] [Related]

  • 6. An improved HPLC assay for the assessment of liver slice metabolic viability using 7-ethoxycoumarin.
    Walsh JS, Patanella JE, Halm KA, Facchine KL.
    Drug Metab Dispos; 1995 Aug; 23(8):869-74. PubMed ID: 7493555
    [Abstract] [Full Text] [Related]

  • 7. Drug-metabolizing activity of human and rat liver, lung, kidney and intestine slices.
    De Kanter R, De Jager MH, Draaisma AL, Jurva JU, Olinga P, Meijer DK, Groothuis GM.
    Xenobiotica; 2002 May; 32(5):349-62. PubMed ID: 12065058
    [Abstract] [Full Text] [Related]

  • 8. Metabolism of dichlorobenzenes in organ cultured liver slices.
    Fisher R, McCarthy S, Sipes IG, Hanzlik RP, Brendel K.
    Adv Exp Med Biol; 1991 May; 283():717-23. PubMed ID: 2069046
    [Abstract] [Full Text] [Related]

  • 9. Short-term maintenance of phase I and II metabolism in precision-cut liver slices in dynamic organ culture.
    Ekins S.
    Drug Metab Dispos; 1996 Mar; 24(3):364-6. PubMed ID: 8820429
    [Abstract] [Full Text] [Related]

  • 10. Characterization of rat small intestinal and colon precision-cut slices as an in vitro system for drug metabolism and induction studies.
    van de Kerkhof EG, de Graaf IA, de Jager MH, Meijer DK, Groothuis GM.
    Drug Metab Dispos; 2005 Nov; 33(11):1613-20. PubMed ID: 16051733
    [Abstract] [Full Text] [Related]

  • 11. The metabolism of 7-ethoxycoumarin in primary maintenance cultures of adult rat hepatocytes.
    Fry JR, Bridges JW.
    Naunyn Schmiedebergs Arch Pharmacol; 1980 Feb; 311(1):85-90. PubMed ID: 7366743
    [Abstract] [Full Text] [Related]

  • 12. Prediction of whole-body metabolic clearance of drugs through the combined use of slices from rat liver, lung, kidney, small intestine and colon.
    De Kanter R, Monshouwer M, Draaisma AL, De Jager MH, de Graaf IA, Proost JH, Meijer DK, Groothuis GM.
    Xenobiotica; 2004 Mar; 34(3):229-41. PubMed ID: 15204696
    [Abstract] [Full Text] [Related]

  • 13. Tissue slices revisited: evaluation and development of a short-term incubation for integrated drug metabolism.
    Thohan S, Zurich MC, Chung H, Weiner M, Kane AS, Rosen GM.
    Drug Metab Dispos; 2001 Oct; 29(10):1337-42. PubMed ID: 11560878
    [Abstract] [Full Text] [Related]

  • 14. Innovative methods to study human intestinal drug metabolism in vitro: precision-cut slices compared with ussing chamber preparations.
    van de Kerkhof EG, Ungell AL, Sjöberg AK, de Jager MH, Hilgendorf C, de Graaf IA, Groothuis GM.
    Drug Metab Dispos; 2006 Nov; 34(11):1893-902. PubMed ID: 16914511
    [Abstract] [Full Text] [Related]

  • 15. Hydrogel embedding of precision-cut liver slices in a microfluidic device improves drug metabolic activity.
    van Midwoud PM, Merema MT, Verweij N, Groothuis GM, Verpoorte E.
    Biotechnol Bioeng; 2011 Jun; 108(6):1404-12. PubMed ID: 21274846
    [Abstract] [Full Text] [Related]

  • 16. Xenobiotic metabolism in rat, dog, and human precision-cut liver slices, freshly isolated hepatocytes, and vitrified precision-cut liver slices.
    Ekins S, Williams JA, Murray GI, Burke MD, Marchant NC, Engeset J, Hawksworth GM.
    Drug Metab Dispos; 1996 Sep; 24(9):990-5. PubMed ID: 8886609
    [Abstract] [Full Text] [Related]

  • 17. On-line HPLC analysis system for metabolism and inhibition studies in precision-cut liver slices.
    van Midwoud PM, Janssen J, Merema MT, de Graaf IA, Groothuis GM, Verpoorte E.
    Anal Chem; 2011 Jan 01; 83(1):84-91. PubMed ID: 21128611
    [Abstract] [Full Text] [Related]

  • 18. A new technique for preparing precision-cut slices from small intestine and colon for drug biotransformation studies.
    de Kanter R, Tuin A, van de Kerkhof E, Martignoni M, Draaisma AL, de Jager MH, de Graaf IA, Meijer DK, Groothuis GM.
    J Pharmacol Toxicol Methods; 2005 Jan 01; 51(1):65-72. PubMed ID: 15596116
    [Abstract] [Full Text] [Related]

  • 19. Biotransformation activity in vitrified human liver slices.
    Wishnies SM, Parrish AR, Sipes IG, Gandolfi AJ, Putnam CW, Krumdieck CL, Brendel K.
    Cryobiology; 1991 Jun 01; 28(3):216-26. PubMed ID: 1864080
    [Abstract] [Full Text] [Related]

  • 20. Phase I and phase II metabolic activities are retained in liver slices from mouse, rat, dog, monkey and human after cryopreservation.
    Martignoni M, Monshouwer M, de Kanter R, Pezzetta D, Moscone A, Grossi P.
    Toxicol In Vitro; 2004 Feb 01; 18(1):121-8. PubMed ID: 14630070
    [Abstract] [Full Text] [Related]

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