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Journal Abstract Search

411 related items for PubMed ID: 18627350

  • 1. Role of the multifunctional DNA repair and redox signaling protein Ape1/Ref-1 in cancer and endothelial cells: small-molecule inhibition of the redox function of Ape1.
    Luo M, Delaplane S, Jiang A, Reed A, He Y, Fishel M, Nyland RL, Borch RF, Qiao X, Georgiadis MM, Kelley MR.
    Antioxid Redox Signal; 2008 Nov; 10(11):1853-67. PubMed ID: 18627350
    [Abstract] [Full Text] [Related]

  • 2. Impact of APE1/Ref-1 redox inhibition on pancreatic tumor growth.
    Fishel ML, Jiang Y, Rajeshkumar NV, Scandura G, Sinn AL, He Y, Shen C, Jones DR, Pollok KE, Ivan M, Maitra A, Kelley MR.
    Mol Cancer Ther; 2011 Sep; 10(9):1698-708. PubMed ID: 21700832
    [Abstract] [Full Text] [Related]

  • 3. Soy isoflavones augment radiation effect by inhibiting APE1/Ref-1 DNA repair activity in non-small cell lung cancer.
    Singh-Gupta V, Joiner MC, Runyan L, Yunker CK, Sarkar FH, Miller S, Gadgeel SM, Konski AA, Hillman GG.
    J Thorac Oncol; 2011 Apr; 6(4):688-98. PubMed ID: 21325978
    [Abstract] [Full Text] [Related]

  • 4. The DNA base excision repair protein Ape1/Ref-1 as a therapeutic and chemopreventive target.
    Fishel ML, Kelley MR.
    Mol Aspects Med; 2007 Apr; 28(3-4):375-95. PubMed ID: 17560642
    [Abstract] [Full Text] [Related]

  • 5. Functional analysis of novel analogues of E3330 that block the redox signaling activity of the multifunctional AP endonuclease/redox signaling enzyme APE1/Ref-1.
    Kelley MR, Luo M, Reed A, Su D, Delaplane S, Borch RF, Nyland RL, Gross ML, Georgiadis MM.
    Antioxid Redox Signal; 2011 Apr 15; 14(8):1387-401. PubMed ID: 20874257
    [Abstract] [Full Text] [Related]

  • 6. Small-molecule inhibitor of the AP endonuclease 1/REF-1 E3330 inhibits pancreatic cancer cell growth and migration.
    Zou GM, Maitra A.
    Mol Cancer Ther; 2008 Jul 15; 7(7):2012-21. PubMed ID: 18645011
    [Abstract] [Full Text] [Related]

  • 7. Inhibitors of nuclease and redox activity of apurinic/apyrimidinic endonuclease 1/redox effector factor 1 (APE1/Ref-1).
    Laev SS, Salakhutdinov NF, Lavrik OI.
    Bioorg Med Chem; 2017 May 01; 25(9):2531-2544. PubMed ID: 28161249
    [Abstract] [Full Text] [Related]

  • 8. A new APE1/Ref-1-dependent pathway leading to reduction of NF-kappaB and AP-1, and activation of their DNA-binding activity.
    Ando K, Hirao S, Kabe Y, Ogura Y, Sato I, Yamaguchi Y, Wada T, Handa H.
    Nucleic Acids Res; 2008 Aug 01; 36(13):4327-36. PubMed ID: 18586825
    [Abstract] [Full Text] [Related]

  • 9. Suppression of choroidal neovascularization through inhibition of APE1/Ref-1 redox activity.
    Li Y, Liu X, Zhou T, Kelley MR, Edwards PA, Gao H, Qiao X.
    Invest Ophthalmol Vis Sci; 2014 Jun 26; 55(7):4461-9. PubMed ID: 24970265
    [Abstract] [Full Text] [Related]

  • 10. Elevated and altered expression of the multifunctional DNA base excision repair and redox enzyme Ape1/ref-1 in prostate cancer.
    Kelley MR, Cheng L, Foster R, Tritt R, Jiang J, Broshears J, Koch M.
    Clin Cancer Res; 2001 Apr 26; 7(4):824-30. PubMed ID: 11309329
    [Abstract] [Full Text] [Related]

  • 11. APE1/Ref-1 regulates STAT3 transcriptional activity and APE1/Ref-1-STAT3 dual-targeting effectively inhibits pancreatic cancer cell survival.
    Cardoso AA, Jiang Y, Luo M, Reed AM, Shahda S, He Y, Maitra A, Kelley MR, Fishel ML.
    PLoS One; 2012 Apr 26; 7(10):e47462. PubMed ID: 23094050
    [Abstract] [Full Text] [Related]

  • 12. Specific inhibition of the redox activity of ape1/ref-1 by e3330 blocks tnf-α-induced activation of IL-8 production in liver cancer cell lines.
    Cesaratto L, Codarin E, Vascotto C, Leonardi A, Kelley MR, Tiribelli C, Tell G.
    PLoS One; 2013 Apr 26; 8(8):e70909. PubMed ID: 23967134
    [Abstract] [Full Text] [Related]

  • 13. Regulation of HIF1α under Hypoxia by APE1/Ref-1 Impacts CA9 Expression: Dual Targeting in Patient-Derived 3D Pancreatic Cancer Models.
    Logsdon DP, Grimard M, Luo M, Shahda S, Jiang Y, Tong Y, Yu Z, Zyromski N, Schipani E, Carta F, Supuran CT, Korc M, Ivan M, Kelley MR, Fishel ML.
    Mol Cancer Ther; 2016 Nov 26; 15(11):2722-2732. PubMed ID: 27535970
    [Abstract] [Full Text] [Related]

  • 14. Antitumor Activity and Mechanistic Characterization of APE1/Ref-1 Inhibitors in Bladder Cancer.
    Fishel ML, Xia H, McGeown J, McIlwain DW, Elbanna M, Craft AA, Kaimakliotis HZ, Sandusky GE, Zhang C, Pili R, Kelley MR, Jerde TJ.
    Mol Cancer Ther; 2019 Nov 26; 18(11):1947-1960. PubMed ID: 31413178
    [Abstract] [Full Text] [Related]

  • 15. NMR studies reveal an unexpected binding site for a redox inhibitor of AP endonuclease 1.
    Manvilla BA, Wauchope O, Seley-Radtke KL, Drohat AC.
    Biochemistry; 2011 Dec 06; 50(48):10540-9. PubMed ID: 22032234
    [Abstract] [Full Text] [Related]

  • 16. The Ape-1/Ref-1 redox antagonist E3330 inhibits the growth of tumor endothelium and endothelial progenitor cells: therapeutic implications in tumor angiogenesis.
    Zou GM, Karikari C, Kabe Y, Handa H, Anders RA, Maitra A.
    J Cell Physiol; 2009 Apr 06; 219(1):209-18. PubMed ID: 19097035
    [Abstract] [Full Text] [Related]

  • 17. Inhibition of APE1/Ref-1 redox activity rescues human retinal pigment epithelial cells from oxidative stress and reduces choroidal neovascularization.
    Li Y, Liu X, Zhou T, Kelley MR, Edwards P, Gao H, Qiao X.
    Redox Biol; 2014 Apr 06; 2():485-94. PubMed ID: 24624338
    [Abstract] [Full Text] [Related]

  • 18. Knock-in reconstitution studies reveal an unexpected role of Cys-65 in regulating APE1/Ref-1 subcellular trafficking and function.
    Vascotto C, Bisetto E, Li M, Zeef LA, D'Ambrosio C, Domenis R, Comelli M, Delneri D, Scaloni A, Altieri F, Mavelli I, Quadrifoglio F, Kelley MR, Tell G.
    Mol Biol Cell; 2011 Oct 06; 22(20):3887-901. PubMed ID: 21865600
    [Abstract] [Full Text] [Related]

  • 19. Going APE over ref-1.
    Evans AR, Limp-Foster M, Kelley MR.
    Mutat Res; 2000 Oct 16; 461(2):83-108. PubMed ID: 11018583
    [Abstract] [Full Text] [Related]

  • 20. Design and synthesis of novel quinone inhibitors targeted to the redox function of apurinic/apyrimidinic endonuclease 1/redox enhancing factor-1 (Ape1/ref-1).
    Nyland RL, Luo M, Kelley MR, Borch RF.
    J Med Chem; 2010 Feb 11; 53(3):1200-10. PubMed ID: 20067291
    [Abstract] [Full Text] [Related]

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