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98 related items for PubMed ID: 18633430
1. A novel arsenical has antitumor activity toward As2O3-resistant and MRP1/ABCC1-overexpressing cell lines. Diaz Z, Mann KK, Marcoux S, Kourelis M, Colombo M, Komarnitsky PB, Miller WH. Leukemia; 2008 Oct; 22(10):1853-63. PubMed ID: 18633430 [Abstract] [Full Text] [Related]
2. Darinaparsin induces a unique cellular response and is active in an arsenic trioxide-resistant myeloma cell line. Matulis SM, Morales AA, Yehiayan L, Croutch C, Gutman D, Cai Y, Lee KP, Boise LH. Mol Cancer Ther; 2009 May; 8(5):1197-206. PubMed ID: 19417148 [Abstract] [Full Text] [Related]
3. Pharmacologic inhibitors of extracellular signal-regulated kinase (ERKs) and c-Jun NH(2)-terminal kinase (JNK) decrease glutathione content and sensitize human promonocytic leukemia cells to arsenic trioxide-induced apoptosis. Ramos AM, Fernandez C, Amrán D, Esteban D, de Blas E, Palacios MA, Aller P. J Cell Physiol; 2006 Dec; 209(3):1006-15. PubMed ID: 16972261 [Abstract] [Full Text] [Related]
4. Darinaparsin: a novel organic arsenical with promising anticancer activity. Mann KK, Wallner B, Lossos IS, Miller WH. Expert Opin Investig Drugs; 2009 Nov; 18(11):1727-34. PubMed ID: 19780704 [Abstract] [Full Text] [Related]
6. JNK activation is a mediator of arsenic trioxide-induced apoptosis in acute promyelocytic leukemia cells. Davison K, Mann KK, Waxman S, Miller WH. Blood; 2004 May 01; 103(9):3496-502. PubMed ID: 14701702 [Abstract] [Full Text] [Related]
7. Tumor growth inhibition by arsenic trioxide (As2O3) in the orthotopic metastasis model of androgen-independent prostate cancer. Maeda H, Hori S, Nishitoh H, Ichijo H, Ogawa O, Kakehi Y, Kakizuka A. Cancer Res; 2001 Jul 15; 61(14):5432-40. PubMed ID: 11454688 [Abstract] [Full Text] [Related]
8. Glutathione depletion overcomes resistance to arsenic trioxide in arsenic-resistant cell lines. Davison K, Côté S, Mader S, Miller WH. Leukemia; 2003 May 15; 17(5):931-40. PubMed ID: 12750708 [Abstract] [Full Text] [Related]
9. Retinoic acid, but not arsenic trioxide, degrades the PLZF/RARalpha fusion protein, without inducing terminal differentiation or apoptosis, in a RA-therapy resistant t(11;17)(q23;q21) APL patient. Koken MH, Daniel MT, Gianni M, Zelent A, Licht J, Buzyn A, Minard P, Degos L, Varet B, de Thé H. Oncogene; 1999 Jan 28; 18(4):1113-8. PubMed ID: 10023688 [Abstract] [Full Text] [Related]
10. Elimination of the differential chemoresistance between the murine B-cell lymphoma LY-ar and LY-as cell lines after arsenic (As2O3) exposure via the overexpression of gsto1 (p28). Giri U, Terry NH, Kala SV, Lieberman MW, Story MD. Cancer Chemother Pharmacol; 2005 Jun 28; 55(6):511-21. PubMed ID: 15761769 [Abstract] [Full Text] [Related]
11. Role of GSTP1-1 in mediating the effect of As2O3 in the Acute Promyelocytic Leukemia cell line NB4. Bernardini S, Nuccetelli M, Noguera NI, Bellincampi L, Lunghi P, Bonati A, Mann K, Miller WH, Federici G, Lo Coco F. Ann Hematol; 2006 Oct 28; 85(10):681-7. PubMed ID: 16733740 [Abstract] [Full Text] [Related]
12. The novel organic arsenical darinaparsin induces MAPK-mediated and SHP1-dependent cell death in T-cell lymphoma and Hodgkin lymphoma cells and human xenograft models. Ravi D, Bhalla S, Gartenhaus RB, Crombie J, Kandela I, Sharma J, Mazar A, Evens AM. Clin Cancer Res; 2014 Dec 01; 20(23):6023-33. PubMed ID: 25316819 [Abstract] [Full Text] [Related]
13. Darinaparsin: solid tumor hypoxic cytotoxin and radiosensitizer. Tian J, Zhao H, Nolley R, Reese SW, Young SR, Li X, Peehl DM, Knox SJ. Clin Cancer Res; 2012 Jun 15; 18(12):3366-76. PubMed ID: 22535156 [Abstract] [Full Text] [Related]
14. Buthionine sulfoximine enhancement of arsenic trioxide-induced apoptosis in leukemia and lymphoma cells is mediated via activation of c-Jun NH2-terminal kinase and up-regulation of death receptors. Chen D, Chan R, Waxman S, Jing Y. Cancer Res; 2006 Dec 01; 66(23):11416-23. PubMed ID: 17145888 [Abstract] [Full Text] [Related]
15. Arsenic trioxide-induced apoptosis is independent of stress-responsive signaling pathways but sensitive to inhibition of inducible nitric oxide synthase in HepG2 cells. Kang SH, Song JH, Kang HK, Kang JH, Kim SJ, Kang HW, Lee YK, Park DB. Exp Mol Med; 2003 Apr 30; 35(2):83-90. PubMed ID: 12754411 [Abstract] [Full Text] [Related]
16. Phosphorylation of PML by mitogen-activated protein kinases plays a key role in arsenic trioxide-mediated apoptosis. Hayakawa F, Privalsky ML. Cancer Cell; 2004 Apr 30; 5(4):389-401. PubMed ID: 15093545 [Abstract] [Full Text] [Related]
17. [Experimental study of low dose arsenic trioxide in treatment of patients with acute promyelocytic leukemia]. Jia PM, Zhu Q, Yu Y, Chen GQ, Chen SJ, Chen Z, Wang ZY, Tong JH. Ai Zheng; 2002 Apr 30; 21(4):337-40. PubMed ID: 12452006 [Abstract] [Full Text] [Related]
18. S-Dimethylarsino-glutathione (darinaparsin®) targets histone H3.3, leading to TRAIL-induced apoptosis in leukemia cells. Xu X, Wang H, Li H, Hu X, Zhang Y, Guan X, Toy PH, Sun H. Chem Commun (Camb); 2019 Oct 29; 55(87):13120-13123. PubMed ID: 31616884 [Abstract] [Full Text] [Related]
19. Arsenic trioxide induces apoptosis through JNK and ERK in human mesothelioma cells. Eguchi R, Fujimori Y, Takeda H, Tabata C, Ohta T, Kuribayashi K, Fukuoka K, Nakano T. J Cell Physiol; 2011 Mar 29; 226(3):762-8. PubMed ID: 20799280 [Abstract] [Full Text] [Related]
20. Chemical and clinical development of darinaparsin, a novel organic arsenic derivative. Quintás-Cardama A, Verstovsek S, Freireich E, Kantarjian H, Chen YW, Zingaro R. Anticancer Agents Med Chem; 2008 Dec 29; 8(8):904-9. PubMed ID: 19075572 [Abstract] [Full Text] [Related] Page: [Next] [New Search]