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Journal Abstract Search

277 related items for PubMed ID: 18635576

  • 1. Pharmacological manipulation of gain-of-function and dominant-negative mechanisms in rhodopsin retinitis pigmentosa.
    Mendes HF, Cheetham ME.
    Hum Mol Genet; 2008 Oct 01; 17(19):3043-54. PubMed ID: 18635576
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  • 2. Pharmacological manipulation of rhodopsin retinitis pigmentosa.
    Mendes HF, Zaccarini R, Cheetham ME.
    Adv Exp Med Biol; 2010 Oct 01; 664():317-23. PubMed ID: 20238031
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  • 3. Hammerhead ribozymes designed to cleave all human rod opsin mRNAs which cause autosomal dominant retinitis pigmentosa.
    Sullivan JM, Pietras KM, Shin BJ, Misasi JN.
    Mol Vis; 2002 Apr 08; 8():102-13. PubMed ID: 11961505
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  • 4. Molecular mechanisms of rhodopsin retinitis pigmentosa and the efficacy of pharmacological rescue.
    Krebs MP, Holden DC, Joshi P, Clark CL, Lee AH, Kaushal S.
    J Mol Biol; 2010 Feb 05; 395(5):1063-78. PubMed ID: 19913029
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  • 7. Inherent instability of the retinitis pigmentosa P23H mutant opsin.
    Chen Y, Jastrzebska B, Cao P, Zhang J, Wang B, Sun W, Yuan Y, Feng Z, Palczewski K.
    J Biol Chem; 2014 Mar 28; 289(13):9288-303. PubMed ID: 24515108
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  • 8. Pharmacological chaperone-mediated in vivo folding and stabilization of the P23H-opsin mutant associated with autosomal dominant retinitis pigmentosa.
    Noorwez SM, Kuksa V, Imanishi Y, Zhu L, Filipek S, Palczewski K, Kaushal S.
    J Biol Chem; 2003 Apr 18; 278(16):14442-14450. PubMed ID: 12566452
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  • 10. Probing mechanisms of photoreceptor degeneration in a new mouse model of the common form of autosomal dominant retinitis pigmentosa due to P23H opsin mutations.
    Sakami S, Maeda T, Bereta G, Okano K, Golczak M, Sumaroka A, Roman AJ, Cideciyan AV, Jacobson SG, Palczewski K.
    J Biol Chem; 2011 Mar 25; 286(12):10551-67. PubMed ID: 21224384
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  • 15. Identification of Small Molecular Chaperones Binding P23H Mutant Opsin through an In Silico Structure-Based Approach.
    Picarazzi F, Zuanon M, Pasqualetto G, Cammarone S, Romeo I, Young MT, Brancale A, Bassetto M, Mori M.
    J Chem Inf Model; 2022 Nov 28; 62(22):5794-5805. PubMed ID: 36367985
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  • 16. A high-throughput screening method for small-molecule pharmacologic chaperones of misfolded rhodopsin.
    Noorwez SM, Ostrov DA, McDowell JH, Krebs MP, Kaushal S.
    Invest Ophthalmol Vis Sci; 2008 Jul 28; 49(7):3224-30. PubMed ID: 18378578
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  • 18. The heat-shock response co-inducer arimoclomol protects against retinal degeneration in rhodopsin retinitis pigmentosa.
    Parfitt DA, Aguila M, McCulley CH, Bevilacqua D, Mendes HF, Athanasiou D, Novoselov SS, Kanuga N, Munro PM, Coffey PJ, Kalmar B, Greensmith L, Cheetham ME.
    Cell Death Dis; 2014 May 22; 5(5):e1236. PubMed ID: 24853414
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  • 19. BiP prevents rod opsin aggregation.
    Athanasiou D, Kosmaoglou M, Kanuga N, Novoselov SS, Paton AW, Paton JC, Chapple JP, Cheetham ME.
    Mol Biol Cell; 2012 Sep 22; 23(18):3522-31. PubMed ID: 22855534
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  • 20. A dual role for EDEM1 in the processing of rod opsin.
    Kosmaoglou M, Kanuga N, Aguilà M, Garriga P, Cheetham ME.
    J Cell Sci; 2009 Dec 15; 122(Pt 24):4465-72. PubMed ID: 19934218
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