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161 related items for PubMed ID: 18638486
1. Structural determinants of the ADAM inhibition by TIMP-3: crystal structure of the TACE-N-TIMP-3 complex. Wisniewska M, Goettig P, Maskos K, Belouski E, Winters D, Hecht R, Black R, Bode W. J Mol Biol; 2008 Sep 19; 381(5):1307-19. PubMed ID: 18638486 [Abstract] [Full Text] [Related]
2. Mapping and characterization of the functional epitopes of tissue inhibitor of metalloproteinases (TIMP)-3 using TIMP-1 as the scaffold: a new frontier in TIMP engineering. Lee MH, Maskos K, Knäuper V, Dodds P, Murphy G. Protein Sci; 2002 Oct 19; 11(10):2493-503. PubMed ID: 12237470 [Abstract] [Full Text] [Related]
3. Tailoring tissue inhibitor of metalloproteinases-3 to overcome the weakening effects of the cysteine-rich domains of tumour necrosis factor-alpha converting enzyme. Lee MH, Dodds P, Verma V, Maskos K, Knäuper V, Murphy G. Biochem J; 2003 Apr 15; 371(Pt 2):369-76. PubMed ID: 12556225 [Abstract] [Full Text] [Related]
5. Engineering N-terminal domain of tissue inhibitor of metalloproteinase (TIMP)-3 to be a better inhibitor against tumour necrosis factor-alpha-converting enzyme. Lee MH, Verma V, Maskos K, Nath D, Knäuper V, Dodds P, Amour A, Murphy G. Biochem J; 2002 May 15; 364(Pt 1):227-34. PubMed ID: 11988096 [Abstract] [Full Text] [Related]
6. The C-terminal domains of TACE weaken the inhibitory action of N-TIMP-3. Lee MH, Verma V, Maskos K, Becherer JD, Knäuper V, Dodds P, Amour A, Murphy G. FEBS Lett; 2002 Jun 05; 520(1-3):102-6. PubMed ID: 12044879 [Abstract] [Full Text] [Related]
7. Total conversion of tissue inhibitor of metalloproteinase (TIMP) for specific metalloproteinase targeting: fine-tuning TIMP-4 for optimal inhibition of tumor necrosis factor-{alpha}-converting enzyme. Lee MH, Rapti M, Murphy G. J Biol Chem; 2005 Apr 22; 280(16):15967-75. PubMed ID: 15713681 [Abstract] [Full Text] [Related]
8. Full-length and N-TIMP-3 display equal inhibitory activities toward TNF-alpha convertase. Lee MH, Knäuper V, Becherer JD, Murphy G. Biochem Biophys Res Commun; 2001 Jan 26; 280(3):945-50. PubMed ID: 11162616 [Abstract] [Full Text] [Related]
9. Delineating the molecular basis of the inactivity of tissue inhibitor of metalloproteinase-2 against tumor necrosis factor-alpha-converting enzyme. Lee MH, Rapti M, Murphy G. J Biol Chem; 2004 Oct 22; 279(43):45121-9. PubMed ID: 15308656 [Abstract] [Full Text] [Related]
10. Drosophila TIMP is a potent inhibitor of MMPs and TACE: similarities in structure and function to TIMP-3. Wei S, Xie Z, Filenova E, Brew K. Biochemistry; 2003 Oct 28; 42(42):12200-7. PubMed ID: 14567681 [Abstract] [Full Text] [Related]
11. Selective inhibition of ADAM12 catalytic activity through engineering of tissue inhibitor of metalloproteinase 2 (TIMP-2). Kveiborg M, Jacobsen J, Lee MH, Nagase H, Wewer UM, Murphy G. Biochem J; 2010 Aug 15; 430(1):79-86. PubMed ID: 20533908 [Abstract] [Full Text] [Related]
12. Crystal structure of the complex formed by the membrane type 1-matrix metalloproteinase with the tissue inhibitor of metalloproteinases-2, the soluble progelatinase A receptor. Fernandez-Catalan C, Bode W, Huber R, Turk D, Calvete JJ, Lichte A, Tschesche H, Maskos K. EMBO J; 1998 Sep 01; 17(17):5238-48. PubMed ID: 9724659 [Abstract] [Full Text] [Related]
13. Interleukin-10 regulates TNF-alpha-converting enzyme (TACE/ADAM-17) involving a TIMP-3 dependent and independent mechanism. Brennan FM, Green P, Amjadi P, Robertshaw HJ, Alvarez-Iglesias M, Takata M. Eur J Immunol; 2008 Apr 01; 38(4):1106-17. PubMed ID: 18383040 [Abstract] [Full Text] [Related]
14. Reactive-site mutants of N-TIMP-3 that selectively inhibit ADAMTS-4 and ADAMTS-5: biological and structural implications. Lim NH, Kashiwagi M, Visse R, Jones J, Enghild JJ, Brew K, Nagase H. Biochem J; 2010 Oct 01; 431(1):113-22. PubMed ID: 20645923 [Abstract] [Full Text] [Related]
15. Flexibility and variability of TIMP binding: X-ray structure of the complex between collagenase-3/MMP-13 and TIMP-2. Maskos K, Lang R, Tschesche H, Bode W. J Mol Biol; 2007 Mar 02; 366(4):1222-31. PubMed ID: 17196980 [Abstract] [Full Text] [Related]
16. Structure-based rational design of peptide hydroxamic acid inhibitors to target tumor necrosis factor-α converting enzyme as potential therapeutics for hepatitis. Wu D, Gu Q, Zhao N, Xia F, Li Z. J Drug Target; 2015 Dec 02; 23(10):936-42. PubMed ID: 26061299 [Abstract] [Full Text] [Related]