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Journal Abstract Search


93 related items for PubMed ID: 1864224

  • 1. The cellular mechanism of action of bisphosphonates.
    Hughes DE, Mian M, Guilland-Cumming DF, Russell RG.
    Drugs Exp Clin Res; 1991; 17(2):109-14. PubMed ID: 1864224
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  • 4. Mechanisms of action of the bisphosphonates.
    Fleisch H.
    Medicina (B Aires); 1997; 57 Suppl 1():65-75. PubMed ID: 9567358
    [Abstract] [Full Text] [Related]

  • 5. Mechanism of osteoclast mediated bone resorption--rationale for the design of new therapeutics.
    Väänänen K.
    Adv Drug Deliv Rev; 2005 May 25; 57(7):959-71. PubMed ID: 15876398
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  • 6. Nitrogen-containing bisphosphonate mechanism of action.
    Reszka AA, Rodan GA.
    Mini Rev Med Chem; 2004 Sep 25; 4(7):711-9. PubMed ID: 15379639
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  • 7. From molds and macrophages to mevalonate: a decade of progress in understanding the molecular mode of action of bisphosphonates.
    Rogers MJ.
    Calcif Tissue Int; 2004 Dec 25; 75(6):451-61. PubMed ID: 15332174
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  • 9. Molecular mechanisms of action of bisphosphonates: current status.
    Roelofs AJ, Thompson K, Gordon S, Rogers MJ.
    Clin Cancer Res; 2006 Oct 15; 12(20 Pt 2):6222s-6230s. PubMed ID: 17062705
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  • 10. Enhancement of the inhibitory action of APD on the transformation of osteoclast precursors into resorbing cells after dimethylation of the amino group.
    Boonekamp PM, Löwik CW, van der Wee-Pals LJ, van Wijk-van Lennep ML, Bijvoet OL.
    Bone Miner; 1987 Feb 15; 2(1):29-42. PubMed ID: 3504722
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  • 11. Inhibition of osteoclast-like cell formation by bisphosphonates in long-term cultures of human bone marrow.
    Hughes DE, MacDonald BR, Russell RG, Gowen M.
    J Clin Invest; 1989 Jun 15; 83(6):1930-5. PubMed ID: 2524504
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  • 12. Structure-activity relationships for inhibition of farnesyl diphosphate synthase in vitro and inhibition of bone resorption in vivo by nitrogen-containing bisphosphonates.
    Dunford JE, Thompson K, Coxon FP, Luckman SP, Hahn FM, Poulter CD, Ebetino FH, Rogers MJ.
    J Pharmacol Exp Ther; 2001 Feb 15; 296(2):235-42. PubMed ID: 11160603
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  • 13. Recent advances in understanding the mechanism of action of bisphosphonates.
    Coxon FP, Thompson K, Rogers MJ.
    Curr Opin Pharmacol; 2006 Jun 15; 6(3):307-12. PubMed ID: 16650801
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  • 14. Synthesis of NO-donor bisphosphonates and their in-vitro action on bone resorption.
    Lazzarato L, Rolando B, Lolli ML, Tron GC, Fruttero R, Gasco A, Deleide G, Guenther HL.
    J Med Chem; 2005 Mar 10; 48(5):1322-9. PubMed ID: 15743175
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  • 15. A useful method to evaluate bone resorption inhibitors, using osteoclast-like multinucleated cells.
    Sugawara K, Hamada M, Hosoi S, Tamaoki T.
    Anal Biochem; 1998 Jan 15; 255(2):204-10. PubMed ID: 9451505
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  • 16. [Mechanisms of action in bisphosphonates].
    Hoshino H, Yamazaki K.
    Clin Calcium; 2005 Jul 15; 15(7):88-92. PubMed ID: 15995302
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  • 17. Dissociation of the pro-apoptotic effects of bisphosphonates on osteoclasts from their anti-apoptotic effects on osteoblasts/osteocytes with novel analogs.
    Plotkin LI, Manolagas SC, Bellido T.
    Bone; 2006 Sep 15; 39(3):443-52. PubMed ID: 16627025
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  • 18. Structure-activity relationships of new heterocycle-containing bisphosphonates as inhibitors of bone resorption and as inhibitors of growth of Dictyostelium discoideum amoebae.
    Rogers MJ, Xiong X, Brown RJ, Watts DJ, Russell RG, Bayless AV, Ebetino FH.
    Mol Pharmacol; 1995 Feb 15; 47(2):398-402. PubMed ID: 7870050
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  • 20. Synthesis and biological evaluation of novel bisphosphonates with dual activities on bone in vitro.
    Xie Y, Ding H, Qian L, Yan X, Yang C, Xie Y.
    Bioorg Med Chem Lett; 2005 Jul 01; 15(13):3267-70. PubMed ID: 15936189
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