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Journal Abstract Search

183 related items for PubMed ID: 18644999

  • 1. Single-chain antibody/activated BID chimeric protein effectively suppresses HER2-positive tumor growth.
    Qiu XC, Xu YM, Wang F, Fan QY, Wang LF, Ma BA, Jia LT, Zhao J, Meng YL, Yao LB, Chen SY, Yang AG.
    Mol Cancer Ther; 2008 Jul; 7(7):1890-9. PubMed ID: 18644999
    [Abstract] [Full Text] [Related]

  • 2. A novel recombinant immuno-tBid with a furin site effectively suppresses the growth of HER2-positive osteosarcoma cells in vitro.
    Shan LQ, Ma S, Qiu XC, Wang T, Yu SB, Ma BA, Zhou Y, Fan QY, Yang AG.
    Oncol Rep; 2011 Feb; 25(2):325-31. PubMed ID: 21152867
    [Abstract] [Full Text] [Related]

  • 3. Selective cytotoxicity to HER2-positive tumor cells by a recombinant e23sFv-TD-tBID protein containing a furin cleavage sequence.
    Wang F, Ren J, Qiu XC, Wang LF, Zhu Q, Zhang YQ, Huan Y, Meng YL, Yao LB, Chen SY, Xu YM, Yang AG.
    Clin Cancer Res; 2010 Apr 15; 16(8):2284-94. PubMed ID: 20371697
    [Abstract] [Full Text] [Related]

  • 4. scFv-mediated delivery of truncated BID suppresses HER2-positive osteosarcoma growth and metastasis.
    Shan LQ, Qiu XC, Xu YM, Ji ZG, Yang TT, Chen X, Ma BA, Zhou Y, Fan QY, Yang AG.
    Cancer Biol Ther; 2008 Nov 15; 7(11):1717-22. PubMed ID: 18787415
    [Abstract] [Full Text] [Related]

  • 5. A novel recombinant immunocasp-6 fusion gene specifically and efficiently suppresses HER2-overexpressing osteosarcoma.
    Zhou BG, Liu MY, Qiu XC, Xu YM, Fan QY, Yang AG, Zhang Y, Xia H.
    Oncol Rep; 2013 Jan 15; 29(1):276-82. PubMed ID: 23135254
    [Abstract] [Full Text] [Related]

  • 6. A caspase-6 and anti-human epidermal growth factor receptor-2 (HER2) antibody chimeric molecule suppresses the growth of HER2-overexpressing tumors.
    Xu YM, Wang LF, Jia LT, Qiu XC, Zhao J, Yu CJ, Zhang R, Zhu F, Wang CJ, Jin BQ, Chen SY, Yang AG.
    J Immunol; 2004 Jul 01; 173(1):61-7. PubMed ID: 15210759
    [Abstract] [Full Text] [Related]

  • 7. Specific tumoricidal activity of a secreted proapoptotic protein consisting of HER2 antibody and constitutively active caspase-3.
    Jia LT, Zhang LH, Yu CJ, Zhao J, Xu YM, Gui JH, Jin M, Ji ZL, Wen WH, Wang CJ, Chen SY, Yang AG.
    Cancer Res; 2003 Jun 15; 63(12):3257-62. PubMed ID: 12810656
    [Abstract] [Full Text] [Related]

  • 8. A caspase-6 and anti-HER2 antibody chimeric tumor-targeted proapoptotic molecule decreased metastasis of human osteosarcoma.
    Wang LF, Zhou Y, Xu YM, Qiu XC, Zhou BG, Wang F, Long H, Chen X, Yang TT, Ma BA, Fan QY, Yang AG.
    Cancer Invest; 2009 Aug 15; 27(7):774-80. PubMed ID: 19488908
    [Abstract] [Full Text] [Related]

  • 9. Potent killing of HBV-related hepatocellular carcinoma by a chimeric protein of anti-HBsAg single-chain antibody and truncated Bid.
    Yan B, Ouyang Q, Zhao Z, Cao F, Wang T, Jia X, Meng Y, Jiang S, Liu J, Chen R, Jia L, Zhang R, Wen W, Jin B, Chen S, Zhao J, Yang A.
    Biomaterials; 2013 Jul 15; 34(20):4880-9. PubMed ID: 23562050
    [Abstract] [Full Text] [Related]

  • 10. Potent inhibition of human gastric cancer by HER2-directed induction of apoptosis with anti-HER2 antibody and caspase-3 fusion protein.
    Zhang DX, Zhao PT, Xia L, Liu LL, Liang J, Zhai HH, Zhang HB, Guo XG, Wu KC, Xu YM, Jia LT, Yang AG, Chen SY, Fan DM.
    Gut; 2010 Mar 15; 59(3):292-9. PubMed ID: 19951902
    [Abstract] [Full Text] [Related]

  • 11. The caspase-8/Bid/cytochrome c axis links signals from death receptors to mitochondrial reactive oxygen species production.
    Kim WS, Lee KS, Kim JH, Kim CK, Lee G, Choe J, Won MH, Kim TH, Jeoung D, Lee H, Kim JY, Ae Jeong M, Ha KS, Kwon YG, Kim YM.
    Free Radic Biol Med; 2017 Nov 15; 112():567-577. PubMed ID: 28888620
    [Abstract] [Full Text] [Related]

  • 12. The effect of direct translocation across endosomes on the cytotoxicity of the recombinant protein e23sFv-Fdt-casp6 to HER2 positive gastric cancer cells.
    Ren JL, Meng YL, Hu B, Jia LT, Zhang R, Xu YM, Xie QS, Zhang YQ, Jin BQ, Chen SY, Wang T, Yang AG.
    Biomaterials; 2011 Oct 15; 32(30):7641-50. PubMed ID: 21767874
    [Abstract] [Full Text] [Related]

  • 13. Selective proapoptotic activity of a secreted recombinant antibody/AIF fusion protein in carcinomas overexpressing HER2.
    Yu CJ, Jia LT, Meng YL, Zhao J, Zhang Y, Qiu XC, Xu YM, Wen WH, Yao LB, Fan DM, Jin BQ, Chen SY, Yang AG.
    Gene Ther; 2006 Feb 15; 13(4):313-20. PubMed ID: 16267568
    [Abstract] [Full Text] [Related]

  • 14. Secreted antibody/granzyme B fusion protein stimulates selective killing of HER2-overexpressing tumor cells.
    Zhao J, Zhang LH, Jia LT, Zhang L, Xu YM, Wang Z, Yu CJ, Peng WD, Wen WH, Wang CJ, Chen SY, Yang AG.
    J Biol Chem; 2004 May 14; 279(20):21343-8. PubMed ID: 15004021
    [Abstract] [Full Text] [Related]

  • 15. Construction of humanized anti-HER2 single-chain variable fragments (husFvs) and achievement of potent tumor suppression with the reconstituted husFv-Fdt-tBid immunoapoptotin.
    Ou-Yang Q, Yan B, Li A, Hu ZS, Feng JN, Lun XX, Zhang MM, Zhang MD, Wu KC, Xue FF, Yang AG, Zhao J.
    Biomaterials; 2018 Sep 14; 178():170-182. PubMed ID: 29935385
    [Abstract] [Full Text] [Related]

  • 16. Induction of programmed cell death in ErbB2/HER2-expressing cancer cells by targeted delivery of apoptosis-inducing factor.
    Mahmud H, Dälken B, Wels WS.
    Mol Cancer Ther; 2009 Jun 14; 8(6):1526-35. PubMed ID: 19509241
    [Abstract] [Full Text] [Related]

  • 17. Real time single cell analysis of Bid cleavage and Bid translocation during caspase-dependent and neuronal caspase-independent apoptosis.
    Ward MW, Rehm M, Duessmann H, Kacmar S, Concannon CG, Prehn JH.
    J Biol Chem; 2006 Mar 03; 281(9):5837-44. PubMed ID: 16407197
    [Abstract] [Full Text] [Related]

  • 18. Construction and characterization of novel, recombinant immunotoxins targeting the Her2/neu oncogene product: in vitro and in vivo studies.
    Cao Y, Marks JD, Marks JW, Cheung LH, Kim S, Rosenblum MG.
    Cancer Res; 2009 Dec 01; 69(23):8987-95. PubMed ID: 19934334
    [Abstract] [Full Text] [Related]

  • 19. Truncated Bid Regulates Cisplatin Response via Activation of Mitochondrial Apoptosis Pathway in Ovarian Cancer.
    Dai Y, Zhao XJ, Li F, Yuan Y, Yan DM, Cao H, Huang XY, Hu Z, Ma D, Gao QL.
    Hum Gene Ther; 2020 Mar 01; 31(5-6):325-338. PubMed ID: 32024383
    [Abstract] [Full Text] [Related]

  • 20. Dual targeting and enhanced cytotoxicity to HER2-overexpressing tumors by immunoapoptotin-armored mesenchymal stem cells.
    Cai Y, Xi Y, Cao Z, Xiang G, Ni Q, Zhang R, Chang J, Du X, Yang A, Yan B, Zhao J.
    Cancer Lett; 2016 Oct 10; 381(1):104-12. PubMed ID: 27473824
    [Abstract] [Full Text] [Related]

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