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59 related items for PubMed ID: 18645229

  • 1. Pharmacological inhibitors of JNK and ERK kinases SP600125 and U0126 are not appropriate tools for studies of drug metabolism because they activate aryl hydrocarbon receptor.
    Bachleda P, Dvorák Z.
    Gen Physiol Biophys; 2008 Jun; 27(2):143-5. PubMed ID: 18645229
    [Abstract] [Full Text] [Related]

  • 2. JNK inhibitor SP600125 is a partial agonist of human aryl hydrocarbon receptor and induces CYP1A1 and CYP1A2 genes in primary human hepatocytes.
    Dvorak Z, Vrzal R, Henklova P, Jancova P, Anzenbacherova E, Maurel P, Svecova L, Pavek P, Ehrmann J, Havlik R, Bednar P, Lemr K, Ulrichova J.
    Biochem Pharmacol; 2008 Jan 15; 75(2):580-8. PubMed ID: 17959153
    [Abstract] [Full Text] [Related]

  • 3. Muscarinic cholinoceptor-mediated activation of JNK negatively regulates intestinal secretion in mice.
    Khan MR, Islam MT, Yazawa T, Hayashi H, Suzuki Y, Uwada J, Anisuzzaman AS, Taniguchi T.
    J Pharmacol Sci; 2015 Jan 15; 127(1):150-3. PubMed ID: 25704031
    [Abstract] [Full Text] [Related]

  • 4. Aryl hydrocarbon receptor activation and cytochrome P450 1A induction by the mitogen-activated protein kinase inhibitor U0126 in hepatocytes.
    Andrieux L, Langouët S, Fautrel A, Ezan F, Krauser JA, Savouret JF, Guengerich FP, Baffet G, Guillouzo A.
    Mol Pharmacol; 2004 Apr 15; 65(4):934-43. PubMed ID: 15044623
    [Abstract] [Full Text] [Related]

  • 5. Secreted beta-amyloid precursor protein activates microglia via JNK and p38-MAPK.
    Bodles AM, Barger SW.
    Neurobiol Aging; 2005 Jan 15; 26(1):9-16. PubMed ID: 15585341
    [Abstract] [Full Text] [Related]

  • 6. Enhanced phosphorylation of MAPKs by NE promotes TNF-α production by macrophage through α adrenergic receptor.
    Huang JL, Zhang YL, Wang CC, Zhou JR, Ma Q, Wang X, Shen XH, Jiang CL.
    Inflammation; 2012 Apr 15; 35(2):527-34. PubMed ID: 21590324
    [Abstract] [Full Text] [Related]

  • 7. Predominant activation of MAP kinases and pro-destructive/pro-inflammatory features by TNF alpha in early-passage synovial fibroblasts via TNF receptor-1: failure of p38 inhibition to suppress matrix metalloproteinase-1 in rheumatoid arthritis.
    Kunisch E, Gandesiri M, Fuhrmann R, Roth A, Winter R, Kinne RW.
    Ann Rheum Dis; 2007 Aug 15; 66(8):1043-51. PubMed ID: 17223661
    [Abstract] [Full Text] [Related]

  • 8. Eosinophil migration induced by mast cell chymase is mediated by extracellular signal-regulated kinase pathway.
    Terakawa M, Tomimori Y, Goto M, Hayashi Y, Oikawa S, Fukuda Y.
    Biochem Biophys Res Commun; 2005 Jul 15; 332(4):969-75. PubMed ID: 15919053
    [Abstract] [Full Text] [Related]

  • 9. SB203580, a pharmacological inhibitor of p38 MAP kinase transduction pathway activates ERK and JNK MAP kinases in primary cultures of human hepatocytes.
    Henklova P, Vrzal R, Papouskova B, Bednar P, Jancova P, Anzenbacherova E, Ulrichova J, Maurel P, Pavek P, Dvorak Z.
    Eur J Pharmacol; 2008 Sep 28; 593(1-3):16-23. PubMed ID: 18655782
    [Abstract] [Full Text] [Related]

  • 10. Apoptosis induction by oxidized glycated LDL in human retinal capillary pericytes is independent of activation of MAPK signaling pathways.
    Diffley JM, Wu M, Sohn M, Song W, Hammad SM, Lyons TJ.
    Mol Vis; 2009 Sep 28; 15():135-45. PubMed ID: 19158958
    [Abstract] [Full Text] [Related]

  • 11. Mitogen activated protein kinases blockade improves lipopolysaccharide-induced ileal motor disturbances.
    Gonzalo S, Grasa L, Hernández LV, Arruebo MP, Plaza MÁ, Murillo MD.
    Rev Esp Enferm Dig; 2012 Jun 28; 104(6):305-9. PubMed ID: 22738700
    [Abstract] [Full Text] [Related]

  • 12. Porphyromonas gingivalis-related cardiac cell apoptosis was majorly co-activated by p38 and extracellular signal-regulated kinase pathways.
    Lee SD, Wu CC, Kuo WW, Lin JA, Hwang JM, Lu MC, Chen LM, Hsu HH, Wang CK, Chang SH, Huang CY.
    J Periodontal Res; 2006 Feb 28; 41(1):39-46. PubMed ID: 16409254
    [Abstract] [Full Text] [Related]

  • 13. Involvement of MAP kinases in lipopolysaccharide-induced histamine production in RAW 264 cells.
    Hirasawa N, Torigoe M, Ohgawara R, Murakami A, Ohuchi K.
    Life Sci; 2006 Dec 03; 80(1):36-42. PubMed ID: 16978663
    [Abstract] [Full Text] [Related]

  • 14. Role for mitogen-activated protein kinases in phenobarbital-induced expression of cytochrome P450 2B in primary cultures of rat hepatocytes.
    Joannard F, Rissel M, Gilot D, Anderson A, Orfila-Lefeuvre L, Guillouzo A, Atfi A, Lagadic-Gossmann D.
    Toxicol Lett; 2006 Feb 08; 161(1):61-72. PubMed ID: 16154717
    [Abstract] [Full Text] [Related]

  • 15. Cooperation of structurally different aryl hydrocarbon receptor agonists and β-catenin in the regulation of CYP1A expression.
    Vaas S, Kreft L, Schwarz M, Braeuning A.
    Toxicology; 2014 Nov 05; 325():31-41. PubMed ID: 25174530
    [Abstract] [Full Text] [Related]

  • 16. The effects of ZD1839 (Iressa), a highly selective EGFR tyrosine kinase inhibitor, as a radiosensitiser in bile duct carcinoma cell lines.
    Miyata H, Sasaki T, Kuwahara K, Serikawa M, Chayama K.
    Int J Oncol; 2006 Apr 05; 28(4):915-21. PubMed ID: 16525641
    [Abstract] [Full Text] [Related]

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  • 18. The D₁ dopamine receptor agonist, SKF83959, attenuates hydrogen peroxide-induced injury in RGC-5 cells involving the extracellular signal-regulated kinase/p38 pathways.
    Li GY, Li T, Fan B, Zheng YC, Ma TH.
    Mol Vis; 2012 Apr 05; 18():2882-95. PubMed ID: 23233790
    [Abstract] [Full Text] [Related]

  • 19. Transcriptional regulation of VCAM-1 expression by tumor necrosis factor-alpha in human tracheal smooth muscle cells: involvement of MAPKs, NF-kappaB, p300, and histone acetylation.
    Lee CW, Lin WN, Lin CC, Luo SF, Wang JS, Pouyssegur J, Yang CM.
    J Cell Physiol; 2006 Apr 05; 207(1):174-86. PubMed ID: 16288471
    [Abstract] [Full Text] [Related]

  • 20. p21(Cip-1/SDI-1/WAF-1) expression via the mitogen-activated protein kinase signaling pathway in insulin-induced chondrogenic differentiation of ATDC5 cells.
    Nakajima M, Negishi Y, Tanaka H, Kawashima K.
    Biochem Biophys Res Commun; 2004 Aug 06; 320(4):1069-75. PubMed ID: 15249198
    [Abstract] [Full Text] [Related]

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