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338 related items for PubMed ID: 18648086

  • 1. Perfluorocarboxylic acids induce cytochrome P450 enzymes in mouse liver through activation of PPAR-alpha and CAR transcription factors.
    Cheng X, Klaassen CD.
    Toxicol Sci; 2008 Nov; 106(1):29-36. PubMed ID: 18648086
    [Abstract] [Full Text] [Related]

  • 2. Critical role of PPAR-alpha in perfluorooctanoic acid- and perfluorodecanoic acid-induced downregulation of Oatp uptake transporters in mouse livers.
    Cheng X, Klaassen CD.
    Toxicol Sci; 2008 Nov; 106(1):37-45. PubMed ID: 18703564
    [Abstract] [Full Text] [Related]

  • 3. Activation of nuclear receptor CAR by an environmental pollutant perfluorooctanoic acid.
    Abe T, Takahashi M, Kano M, Amaike Y, Ishii C, Maeda K, Kudoh Y, Morishita T, Hosaka T, Sasaki T, Kodama S, Matsuzawa A, Kojima H, Yoshinari K.
    Arch Toxicol; 2017 Jun; 91(6):2365-2374. PubMed ID: 27832320
    [Abstract] [Full Text] [Related]

  • 4. Drug metabolizing enzyme induction pathways in experimental non-alcoholic steatohepatitis.
    Fisher CD, Jackson JP, Lickteig AJ, Augustine LM, Cherrington NJ.
    Arch Toxicol; 2008 Dec; 82(12):959-64. PubMed ID: 18488193
    [Abstract] [Full Text] [Related]

  • 5. The role of mouse and human peroxisome proliferator-activated receptor-α in modulating the hepatic effects of perfluorooctane sulfonate in mice.
    Su S, Billy LJ, Chang S, Gonzalez FJ, Patterson AD, Peters JM.
    Toxicology; 2022 Jan 15; 465():153056. PubMed ID: 34861291
    [Abstract] [Full Text] [Related]

  • 6. Coordinated regulation of hepatic phase I and II drug-metabolizing genes and transporters using AhR-, CAR-, PXR-, PPARα-, and Nrf2-null mice.
    Aleksunes LM, Klaassen CD.
    Drug Metab Dispos; 2012 Jul 15; 40(7):1366-79. PubMed ID: 22496397
    [Abstract] [Full Text] [Related]

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  • 8. Toxicogenomic dissection of the perfluorooctanoic acid transcript profile in mouse liver: evidence for the involvement of nuclear receptors PPAR alpha and CAR.
    Rosen MB, Lee JS, Ren H, Vallanat B, Liu J, Waalkes MP, Abbott BD, Lau C, Corton JC.
    Toxicol Sci; 2008 May 15; 103(1):46-56. PubMed ID: 18281256
    [Abstract] [Full Text] [Related]

  • 9. Sex differences in the circadian variation of cytochrome p450 genes and corresponding nuclear receptors in mouse liver.
    Lu YF, Jin T, Xu Y, Zhang D, Wu Q, Zhang YK, Liu J.
    Chronobiol Int; 2013 Nov 15; 30(9):1135-43. PubMed ID: 23926955
    [Abstract] [Full Text] [Related]

  • 10. Regulation of mouse organic anion-transporting polypeptides (Oatps) in liver by prototypical microsomal enzyme inducers that activate distinct transcription factor pathways.
    Cheng X, Maher J, Dieter MZ, Klaassen CD.
    Drug Metab Dispos; 2005 Sep 15; 33(9):1276-82. PubMed ID: 15919853
    [Abstract] [Full Text] [Related]

  • 11. The environmental estrogen, nonylphenol, activates the constitutive androstane receptor.
    Hernandez JP, Huang W, Chapman LM, Chua S, Moore DD, Baldwin WS.
    Toxicol Sci; 2007 Aug 15; 98(2):416-26. PubMed ID: 17483497
    [Abstract] [Full Text] [Related]

  • 12. Induction of nuclear translocation of constitutive androstane receptor by peroxisome proliferator-activated receptor alpha synthetic ligands in mouse liver.
    Guo D, Sarkar J, Suino-Powell K, Xu Y, Matsumoto K, Jia Y, Yu S, Khare S, Haldar K, Rao MS, Foreman JE, Monga SP, Peters JM, Xu HE, Reddy JK.
    J Biol Chem; 2007 Dec 14; 282(50):36766-76. PubMed ID: 17962186
    [Abstract] [Full Text] [Related]

  • 13. Nrf2- and PPAR alpha-mediated regulation of hepatic Mrp transporters after exposure to perfluorooctanoic acid and perfluorodecanoic acid.
    Maher JM, Aleksunes LM, Dieter MZ, Tanaka Y, Peters JM, Manautou JE, Klaassen CD.
    Toxicol Sci; 2008 Dec 14; 106(2):319-28. PubMed ID: 18757529
    [Abstract] [Full Text] [Related]

  • 14. Expression of hepatic cytochrome P450s and UDP-glucuronosyltransferases in PXR and CAR double humanized mice treated with rifampicin.
    Lee SY, Lee JY, Kim YM, Kim SK, Oh SJ.
    Toxicol Lett; 2015 Jun 01; 235(2):107-15. PubMed ID: 25835148
    [Abstract] [Full Text] [Related]

  • 15. Induction of mouse UDP-glucuronosyltransferase mRNA expression in liver and intestine by activators of aryl-hydrocarbon receptor, constitutive androstane receptor, pregnane X receptor, peroxisome proliferator-activated receptor alpha, and nuclear factor erythroid 2-related factor 2.
    Buckley DB, Klaassen CD.
    Drug Metab Dispos; 2009 Apr 01; 37(4):847-56. PubMed ID: 19144771
    [Abstract] [Full Text] [Related]

  • 16. Hepatic carboxylesterases are differentially regulated in PPARα-null mice treated with perfluorooctanoic acid.
    Wen X, Baker AA, Klaassen CD, Corton JC, Richardson JR, Aleksunes LM.
    Toxicology; 2019 Mar 15; 416():15-22. PubMed ID: 30685356
    [Abstract] [Full Text] [Related]

  • 17. Evidence for the involvement of xenobiotic-responsive nuclear receptors in transcriptional effects upon perfluoroalkyl acid exposure in diverse species.
    Ren H, Vallanat B, Nelson DM, Yeung LWY, Guruge KS, Lam PKS, Lehman-McKeeman LD, Corton JC.
    Reprod Toxicol; 2009 Jun 15; 27(3-4):266-277. PubMed ID: 19162173
    [Abstract] [Full Text] [Related]

  • 18. Specific and overlapping functions of the nuclear hormone receptors CAR and PXR in xenobiotic response.
    Wei P, Zhang J, Dowhan DH, Han Y, Moore DD.
    Pharmacogenomics J; 2002 Jun 15; 2(2):117-26. PubMed ID: 12049174
    [Abstract] [Full Text] [Related]

  • 19. Opposing regulation of cytochrome P450 expression by CAR and PXR in hypothyroid mice.
    Park YJ, Lee EK, Lee YK, Park DJ, Jang HC, Moore DD.
    Toxicol Appl Pharmacol; 2012 Sep 01; 263(2):131-7. PubMed ID: 22503787
    [Abstract] [Full Text] [Related]

  • 20. Characterization of nuclear receptor-mediated murine hepatocarcinogenesis of the herbicide pronamide and its human relevance.
    LeBaron MJ, Rasoulpour RJ, Gollapudi BB, Sura R, Kan HL, Schisler MR, Pottenger LH, Papineni S, Eisenbrandt DL.
    Toxicol Sci; 2014 Nov 01; 142(1):74-92. PubMed ID: 25092647
    [Abstract] [Full Text] [Related]

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