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Journal Abstract Search

276 related items for PubMed ID: 18651729

  • 1. Design, synthesis and biological evaluation of glutathione peptidomimetics as components of anti-Parkinson prodrugs.
    More SS, Vince R.
    J Med Chem; 2008 Aug 14; 51(15):4581-8. PubMed ID: 18651729
    [Abstract] [Full Text] [Related]

  • 2. Large amino acid transporter 1 (LAT1) prodrugs of valproic acid: new prodrug design ideas for central nervous system delivery.
    Peura L, Malmioja K, Laine K, Leppänen J, Gynther M, Isotalo A, Rautio J.
    Mol Pharm; 2011 Oct 03; 8(5):1857-66. PubMed ID: 21770378
    [Abstract] [Full Text] [Related]

  • 3. Design, synthesis and biological evaluation of L-dopa amide derivatives as potential prodrugs for the treatment of Parkinson's disease.
    Zhou T, Hider RC, Jenner P, Campbell B, Hobbs CJ, Rose S, Jairaj M, Tayarani-Binazir KA, Syme A.
    Eur J Med Chem; 2010 Sep 03; 45(9):4035-42. PubMed ID: 20646792
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  • 5. Effects of amino acid chirality and the chemical linker on the cell permeation characteristics of cyclic prodrugs of opioid peptides.
    Liederer BM, Fuchs T, Vander Velde D, Siahaan TJ, Borchardt RT.
    J Med Chem; 2006 Feb 23; 49(4):1261-70. PubMed ID: 16480263
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  • 8. Targeting the delivery of glycan-based paclitaxel prodrugs to cancer cells via glucose transporters.
    Lin YS, Tungpradit R, Sinchaikul S, An FM, Liu DZ, Phutrakul S, Chen ST.
    J Med Chem; 2008 Dec 11; 51(23):7428-41. PubMed ID: 19053781
    [Abstract] [Full Text] [Related]

  • 9. Prodrug design for brain delivery of small- and medium-sized neuropeptides.
    Prokai-Tatrai K, Prokai L.
    Methods Mol Biol; 2011 Dec 11; 789():313-36. PubMed ID: 21922418
    [Abstract] [Full Text] [Related]

  • 10. Polycyclic cage structures as carrier molecules for neuroprotective non-steroidal anti-inflammatory drugs.
    Prins LH, du Preez JL, van Dyk S, Malan SF.
    Eur J Med Chem; 2009 Jun 11; 44(6):2577-82. PubMed ID: 19233517
    [Abstract] [Full Text] [Related]

  • 11. Dipeptidomimetic ketomethylene isosteres as pro-moieties for drug transport via the human intestinal di-/tripeptide transporter hPEPT1: design, synthesis, stability, and biological investigations.
    Våbenø J, Nielsen CU, Ingebrigtsen T, Lejon T, Steffansen B, Luthman K.
    J Med Chem; 2004 Sep 09; 47(19):4755-65. PubMed ID: 15341490
    [Abstract] [Full Text] [Related]

  • 12. Synthesis and evaluation of novel prodrugs of caspase inhibitors.
    Charrier JD, Durrant SJ, Studley J, Lawes L, Weber P.
    Bioorg Med Chem Lett; 2012 Jan 01; 22(1):485-8. PubMed ID: 22104150
    [Abstract] [Full Text] [Related]

  • 13. Application of a novel design paradigm to generate general nonpeptide combinatorial templates mimicking beta-turns: synthesis of ligands for melanocortin receptors.
    Webb TR, Jiang L, Sviridov S, Venegas RE, Vlaskina AV, McGrath D, Tucker J, Wang J, Deschenes A, Li R.
    J Comb Chem; 2007 Jan 01; 9(4):704-10. PubMed ID: 17429950
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  • 14. Metabolism evaluation of biomimetic prodrugs by in vitro models and mass spectrometry.
    Lalanne M, Khoury H, Deroussent A, Bosquet N, Benech H, Clayette P, Couvreur P, Vassal G, Paci A, Andrieux K.
    Int J Pharm; 2009 Sep 11; 379(2):235-43. PubMed ID: 19467308
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  • 15. Orally active oxime derivatives of the dopaminergic prodrug 6-(N,N-di-n-propylamino)-3,4,5,6,7,8-hexahydro-2H-naphthalen-1-one. Synthesis and pharmacological activity.
    Venhuis BJ, Dijkstra D, Wustrow D, Meltzer LT, Wise LD, Johnson SJ, Wikström HV.
    J Med Chem; 2003 Sep 11; 46(19):4136-40. PubMed ID: 12954065
    [Abstract] [Full Text] [Related]

  • 16. [Research of oral prodrugs: opportunities and challenges].
    Cao F, Ping QN, Chen J.
    Yao Xue Xue Bao; 2008 Apr 11; 43(4):343-9. PubMed ID: 18664193
    [Abstract] [Full Text] [Related]

  • 17. [Synthesis of prodrugs of tacrine hydrochloride and evaluation of the stability and biodistribution in mice].
    Jiang Y, Zhang Y, Zhang ZR.
    Yao Xue Xue Bao; 2003 Dec 11; 38(12):962-5. PubMed ID: 15040096
    [Abstract] [Full Text] [Related]

  • 18. Lipophilic pyrazinoic acid amide and ester prodrugs stability, activation and activity against M. tuberculosis.
    Simões MF, Valente E, Gómez MJ, Anes E, Constantino L.
    Eur J Pharm Sci; 2009 Jun 28; 37(3-4):257-63. PubMed ID: 19491013
    [Abstract] [Full Text] [Related]

  • 19. Potential prodrugs of non-steroidal anti-inflammatory agents for targeted drug delivery to the CNS.
    Perioli L, Ambrogi V, Bernardini C, Grandolini G, Ricci M, Giovagnoli S, Rossi C.
    Eur J Med Chem; 2004 Aug 28; 39(8):715-27. PubMed ID: 15276305
    [Abstract] [Full Text] [Related]

  • 20. Synthesis and in vitro biological evaluation of mannose-containing prodrugs derived from clinically used HIV-protease inhibitors with improved transepithelial transport.
    Roche D, Greiner J, Aubertin AM, Vierling P.
    Bioconjug Chem; 2006 Aug 28; 17(6):1568-81. PubMed ID: 17105238
    [Abstract] [Full Text] [Related]

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