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348 related items for PubMed ID: 18662289

  • 1. Pharmacogenomic studies of the anticancer and immunosuppressive thiopurines mercaptopurine and azathioprine.
    Hawwa AF, Millership JS, Collier PS, Vandenbroeck K, McCarthy A, Dempsey S, Cairns C, Collins J, Rodgers C, McElnay JC.
    Br J Clin Pharmacol; 2008 Oct; 66(4):517-28. PubMed ID: 18662289
    [Abstract] [Full Text] [Related]

  • 2. Azathioprine and 6-mercaptopurine pharmacogenetics and metabolite monitoring in inflammatory bowel disease.
    Gearry RB, Barclay ML.
    J Gastroenterol Hepatol; 2005 Aug; 20(8):1149-57. PubMed ID: 16048561
    [Abstract] [Full Text] [Related]

  • 3. Thiopurine methyltransferase activity combined with 6-thioguanine metabolite levels predicts clinical response to thiopurines in patients with inflammatory bowel disease.
    Kwan LY, Devlin SM, Mirocha JM, Papadakis KA.
    Dig Liver Dis; 2008 Jun; 40(6):425-32. PubMed ID: 18304898
    [Abstract] [Full Text] [Related]

  • 4. Thiopurine methyltransferase genotype-phenotype discordance and thiopurine active metabolite formation in childhood acute lymphoblastic leukaemia.
    Lennard L, Cartwright CS, Wade R, Richards SM, Vora A.
    Br J Clin Pharmacol; 2013 Jul; 76(1):125-36. PubMed ID: 23252716
    [Abstract] [Full Text] [Related]

  • 5. Differences between children and adults in thiopurine methyltransferase activity and metabolite formation during thiopurine therapy: possible role of concomitant methotrexate.
    Pettersson B, Almer S, Albertioni F, Söderhäll S, Peterson C.
    Ther Drug Monit; 2002 Jun; 24(3):351-8. PubMed ID: 12021625
    [Abstract] [Full Text] [Related]

  • 6. Liquid chromatography-tandem mass spectrometry analysis of erythrocyte thiopurine nucleotides and effect of thiopurine methyltransferase gene variants on these metabolites in patients receiving azathioprine/6-mercaptopurine therapy.
    Dervieux T, Meyer G, Barham R, Matsutani M, Barry M, Boulieu R, Neri B, Seidman E.
    Clin Chem; 2005 Nov; 51(11):2074-84. PubMed ID: 16166171
    [Abstract] [Full Text] [Related]

  • 7. Review article: recent advances in pharmacogenetics and pharmacokinetics for safe and effective thiopurine therapy in inflammatory bowel disease.
    Moon W, Loftus EV.
    Aliment Pharmacol Ther; 2016 Apr; 43(8):863-883. PubMed ID: 26876431
    [Abstract] [Full Text] [Related]

  • 8. Key factors associated with 6-thioguanine and 6-methylmercaptopurine nucleotide concentrations in children treated by thiopurine for acute leukaemia and inflammatory bowel disease.
    de Beaumais TA, Lorrain S, Mamhoudi N, Simonin M, Martinez Vinson C, Medard Y, Petit A, Jacqz-Aigrain E.
    Br J Clin Pharmacol; 2024 Jan; 90(1):209-219. PubMed ID: 37621013
    [Abstract] [Full Text] [Related]

  • 9. The pharmacokinetic effect of adalimumab on thiopurine metabolism in Crohn's disease patients.
    Wong DR, Pierik M, Seinen ML, van Bodegraven AA, Gilissen LP, Bus P, Bakker JA, Masclee AA, Neef C, Engels LG, Hooymans PM.
    J Crohns Colitis; 2014 Feb; 8(2):120-8. PubMed ID: 23932783
    [Abstract] [Full Text] [Related]

  • 10. Thiopurine drugs in the treatment of childhood leukaemia: the influence of inherited thiopurine methyltransferase activity on drug metabolism and cytotoxicity.
    Lennard L, Welch JC, Lilleyman JS.
    Br J Clin Pharmacol; 1997 Nov; 44(5):455-61. PubMed ID: 9384462
    [Abstract] [Full Text] [Related]

  • 11. Deletion of glutathione-s-transferase m1 reduces azathioprine metabolite concentrations in young patients with inflammatory bowel disease.
    Stocco G, Cuzzoni E, De Iudicibus S, Franca R, Favretto D, Malusà N, Londero M, Cont G, Bartoli F, Martelossi S, Ventura A, Decorti G.
    J Clin Gastroenterol; 2014 Jan; 48(1):43-51. PubMed ID: 23787247
    [Abstract] [Full Text] [Related]

  • 12. Frequency of ITPA gene polymorphisms in Iranian patients with acute lymphoblastic leukemia and prediction of its myelosuppressive effects.
    Azimi F, Mortazavi Y, Alavi S, Khalili M, Ramazani A.
    Leuk Res; 2015 Oct; 39(10):1048-54. PubMed ID: 26242828
    [Abstract] [Full Text] [Related]

  • 13. Thiopurines in inflammatory bowel disease: pharmacogenetics, therapeutic drug monitoring and clinical recommendations.
    Al Hadithy AF, de Boer NK, Derijks LJ, Escher JC, Mulder CJ, Brouwers JR.
    Dig Liver Dis; 2005 Apr; 37(4):282-97. PubMed ID: 15788214
    [Abstract] [Full Text] [Related]

  • 14. [Monitoring of thiopurine methyltransferase and thiopurine metabolites to optimize azathioprine therapy in inflammatory bowel disease].
    Gisbert JP, González-Lama Y, Maté J.
    Gastroenterol Hepatol; 2006 Nov; 29(9):568-83. PubMed ID: 17129552
    [Abstract] [Full Text] [Related]

  • 15. Determinants of mercaptopurine toxicity in paediatric acute lymphoblastic leukemia maintenance therapy.
    Adam de Beaumais T, Fakhoury M, Medard Y, Azougagh S, Zhang D, Yakouben K, Jacqz-Aigrain E.
    Br J Clin Pharmacol; 2011 Apr; 71(4):575-84. PubMed ID: 21395650
    [Abstract] [Full Text] [Related]

  • 16. Review article: the benefits of pharmacogenetics for improving thiopurine therapy in inflammatory bowel disease.
    Chouchana L, Narjoz C, Beaune P, Loriot MA, Roblin X.
    Aliment Pharmacol Ther; 2012 Jan; 35(1):15-36. PubMed ID: 22050052
    [Abstract] [Full Text] [Related]

  • 17. Population pharmacokinetic and pharmacogenetic analysis of 6-mercaptopurine in paediatric patients with acute lymphoblastic leukaemia.
    Hawwa AF, Collier PS, Millership JS, McCarthy A, Dempsey S, Cairns C, McElnay JC.
    Br J Clin Pharmacol; 2008 Dec; 66(6):826-37. PubMed ID: 18823306
    [Abstract] [Full Text] [Related]

  • 18. Thioguanine versus mercaptopurine for therapy of childhood lymphoblastic leukaemia: a comparison of haematological toxicity and drug metabolite concentrations.
    Lancaster DL, Lennard L, Rowland K, Vora AJ, Lilleyman JS.
    Br J Haematol; 1998 Jul; 102(2):439-43. PubMed ID: 9695957
    [Abstract] [Full Text] [Related]

  • 19. The potential influence of 5-aminosalicylic acid on the induction of myelotoxicity during thiopurine therapy in inflammatory bowel disease patients.
    Gao X, Zhang FB, Ding L, Liu H, Wang XD, Chen BL, Bi HC, Xiao YL, Zhao LZ, Chen MH, Huang M, Hu PJ.
    Eur J Gastroenterol Hepatol; 2012 Aug; 24(8):958-64. PubMed ID: 22664938
    [Abstract] [Full Text] [Related]

  • 20. Thiopurine methyltransferase activity influences clinical response to azathioprine in inflammatory bowel disease.
    Cuffari C, Dassopoulos T, Turnbough L, Thompson RE, Bayless TM.
    Clin Gastroenterol Hepatol; 2004 May; 2(5):410-7. PubMed ID: 15118980
    [Abstract] [Full Text] [Related]

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