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154 related items for PubMed ID: 18665154

  • 1. Downregulation of p22phox in retinal pigment epithelial cells inhibits choroidal neovascularization in mice.
    Li Q, Dinculescu A, Shan Z, Miller R, Pang J, Lewin AS, Raizada MK, Hauswirth WW.
    Mol Ther; 2008 Oct; 16(10):1688-94. PubMed ID: 18665154
    [Abstract] [Full Text] [Related]

  • 2. TNF-α mediates choroidal neovascularization by upregulating VEGF expression in RPE through ROS-dependent β-catenin activation.
    Wang H, Han X, Wittchen ES, Hartnett ME.
    Mol Vis; 2016 Oct; 22():116-28. PubMed ID: 26900328
    [Abstract] [Full Text] [Related]

  • 3. Activation of Rap1 inhibits NADPH oxidase-dependent ROS generation in retinal pigment epithelium and reduces choroidal neovascularization.
    Wang H, Jiang Y, Shi D, Quilliam LA, Chrzanowska-Wodnicka M, Wittchen ES, Li DY, Hartnett ME.
    FASEB J; 2014 Jan; 28(1):265-74. PubMed ID: 24043260
    [Abstract] [Full Text] [Related]

  • 4. ROS production and mitochondrial dysfunction driven by PU.1-regulated NOX4-p22phox activation in Aβ-induced retinal pigment epithelial cell injury.
    Sun J, Chen J, Li T, Huang P, Li J, Shen M, Gao M, Sun Y, Liang J, Li X, Wang Y, Xiao Y, Shi X, Hu Y, Feng J, Jia H, Liu T, Sun X.
    Theranostics; 2020 Jan; 10(25):11637-11655. PubMed ID: 33052238
    [Abstract] [Full Text] [Related]

  • 5. Evolution of oxidative stress, inflammation and neovascularization in the choroid and retina in a subretinal lipid induced age-related macular degeneration model.
    Kim SY, Kambhampati SP, Bhutto IA, McLeod DS, Lutty GA, Kannan RM.
    Exp Eye Res; 2021 Feb; 203():108391. PubMed ID: 33307075
    [Abstract] [Full Text] [Related]

  • 6. Subretinal AAV2.COMP-Ang1 suppresses choroidal neovascularization and vascular endothelial growth factor in a murine model of age-related macular degeneration.
    Lambert NG, Zhang X, Rai RR, Uehara H, Choi S, Carroll LS, Das SK, Cahoon JM, Kirk BH, Bentley BM, Ambati BK.
    Exp Eye Res; 2016 Apr; 145():248-257. PubMed ID: 26775053
    [Abstract] [Full Text] [Related]

  • 7. The role of vascular endothelial growth factor-induced activation of NADPH oxidase in choroidal endothelial cells and choroidal neovascularization.
    Monaghan-Benson E, Hartmann J, Vendrov AE, Budd S, Byfield G, Parker A, Ahmad F, Huang W, Runge M, Burridge K, Madamanchi N, Hartnett ME.
    Am J Pathol; 2010 Oct; 177(4):2091-102. PubMed ID: 20802176
    [Abstract] [Full Text] [Related]

  • 8. Reduction of choroidal neovascularization in mice by adeno-associated virus-delivered anti-vascular endothelial growth factor short hairpin RNA.
    Askou AL, Pournaras JA, Pihlmann M, Svalgaard JD, Arsenijevic Y, Kostic C, Bek T, Dagnaes-Hansen F, Mikkelsen JG, Jensen TG, Corydon TJ.
    J Gene Med; 2012 Nov; 14(11):632-41. PubMed ID: 23080553
    [Abstract] [Full Text] [Related]

  • 9. Cell-specific gene therapy driven by an optimized hypoxia-regulated vector reduces choroidal neovascularization.
    Biswal MR, Prentice HM, Smith GW, Zhu P, Tong Y, Dorey CK, Lewin AS, Blanks JC.
    J Mol Med (Berl); 2018 Oct; 96(10):1107-1118. PubMed ID: 30105447
    [Abstract] [Full Text] [Related]

  • 10. Development of gene therapy for treatment of age-related macular degeneration.
    Askou AL.
    Acta Ophthalmol; 2014 Jul; 92 Thesis3():1-38. PubMed ID: 24953666
    [Abstract] [Full Text] [Related]

  • 11. Activation of the Small GTPase Rap1 Inhibits Choroidal Neovascularization by Regulating Cell Junctions and ROS Generation in Rats.
    Li J, Zhang R, Wang C, Wang X, Xu M, Ma J, Shang Q.
    Curr Eye Res; 2018 Jul; 43(7):934-940. PubMed ID: 29601231
    [Abstract] [Full Text] [Related]

  • 12. Subretinal transplantation of retinal pigment epithelium overexpressing fibulin-5 inhibits laser-induced choroidal neovascularization in rats.
    Li F, Zeng Y, Xu H, Yin ZQ.
    Exp Eye Res; 2015 Jul; 136():78-85. PubMed ID: 25983185
    [Abstract] [Full Text] [Related]

  • 13. Optimal Inhibition of Choroidal Neovascularization by scAAV2 with VMD2 Promoter-driven Active Rap1a in the RPE.
    Wang H, Kunz E, Stoddard GJ, Hauswirth WW, Hartnett ME.
    Sci Rep; 2019 Oct 31; 9(1):15732. PubMed ID: 31673119
    [Abstract] [Full Text] [Related]

  • 14. AAV-mediated gene transfer of human X-linked inhibitor of apoptosis protects against oxidative cell death in human RPE cells.
    Shan H, Ji D, Barnard AR, Lipinski DM, You Q, Lee EJ, Kamalden TA, Sun X, MacLaren RE.
    Invest Ophthalmol Vis Sci; 2011 Dec 20; 52(13):9591-7. PubMed ID: 22039248
    [Abstract] [Full Text] [Related]

  • 15. Hypoxia specific SDF-1 expression by retinal pigment epithelium initiates bone marrow-derived cells to participate in Choroidal neovascularization in a laser-induced mouse model.
    Zhang ZX, Wang YS, Shi YY, Hou HY, Zhang C, Cai Y, Dou GR, Yao LB, Li FY.
    Curr Eye Res; 2011 Sep 20; 36(9):838-49. PubMed ID: 21851170
    [Abstract] [Full Text] [Related]

  • 16. Decorin inhibits angiogenic potential of choroid-retinal endothelial cells by downregulating hypoxia-induced Met, Rac1, HIF-1α and VEGF expression in cocultured retinal pigment epithelial cells.
    Du S, Wang S, Wu Q, Hu J, Li T.
    Exp Eye Res; 2013 Nov 20; 116():151-60. PubMed ID: 24016866
    [Abstract] [Full Text] [Related]

  • 17. Galectin-1 promotes choroidal neovascularization and subretinal fibrosis mediated via epithelial-mesenchymal transition.
    Wu D, Kanda A, Liu Y, Kase S, Noda K, Ishida S.
    FASEB J; 2019 Feb 20; 33(2):2498-2513. PubMed ID: 30277820
    [Abstract] [Full Text] [Related]

  • 18. Edaravone is a free radical scavenger that protects against laser-induced choroidal neovascularization in mice and common marmosets.
    Masuda T, Shimazawa M, Takata S, Nakamura S, Tsuruma K, Hara H.
    Exp Eye Res; 2016 May 20; 146():196-205. PubMed ID: 27018216
    [Abstract] [Full Text] [Related]

  • 19. Serine racemase deficiency attenuates choroidal neovascularization and reduces nitric oxide and VEGF levels by retinal pigment epithelial cells.
    Jiang H, Wu M, Liu Y, Song L, Li S, Wang X, Zhang YF, Fang J, Wu S.
    J Neurochem; 2017 Nov 20; 143(3):375-388. PubMed ID: 28892569
    [Abstract] [Full Text] [Related]

  • 20. Inhibition of choroidal neovascularization by adenovirus-mediated delivery of short hairpin RNAs targeting VEGF as a potential therapy for AMD.
    Cashman SM, Bowman L, Christofferson J, Kumar-Singh R.
    Invest Ophthalmol Vis Sci; 2006 Aug 20; 47(8):3496-504. PubMed ID: 16877421
    [Abstract] [Full Text] [Related]

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