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140 related items for PubMed ID: 18665919

  • 1. Thrombin induces activation and translocation of Bid, Bax and Bak to the mitochondria in human platelets.
    Lopez JJ, Salido GM, Pariente JA, Rosado JA.
    J Thromb Haemost; 2008 Oct; 6(10):1780-8. PubMed ID: 18665919
    [Abstract] [Full Text] [Related]

  • 2. BH3-only activator proteins Bid and Bim are dispensable for Bak/Bax-dependent thrombocyte apoptosis induced by Bcl-xL deficiency: molecular requisites for the mitochondrial pathway to apoptosis in platelets.
    Kodama T, Takehara T, Hikita H, Shimizu S, Shigekawa M, Li W, Miyagi T, Hosui A, Tatsumi T, Ishida H, Kanto T, Hiramatsu N, Yin XM, Hayashi N.
    J Biol Chem; 2011 Apr 22; 286(16):13905-13. PubMed ID: 21367852
    [Abstract] [Full Text] [Related]

  • 3. Bid chimeras indicate that most BH3-only proteins can directly activate Bak and Bax, and show no preference for Bak versus Bax.
    Hockings C, Anwari K, Ninnis RL, Brouwer J, O'Hely M, Evangelista M, Hinds MG, Czabotar PE, Lee EF, Fairlie WD, Dewson G, Kluck RM.
    Cell Death Dis; 2015 Apr 23; 6(4):e1735. PubMed ID: 25906158
    [Abstract] [Full Text] [Related]

  • 4. Erlotinib induces mitochondrial-mediated apoptosis in human H3255 non-small-cell lung cancer cells with epidermal growth factor receptorL858R mutation through mitochondrial oxidative phosphorylation-dependent activation of BAX and BAK.
    Ling YH, Lin R, Perez-Soler R.
    Mol Pharmacol; 2008 Sep 23; 74(3):793-806. PubMed ID: 18524889
    [Abstract] [Full Text] [Related]

  • 5. Involvement of proapoptotic molecules Bax and Bak in tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced mitochondrial disruption and apoptosis: differential regulation of cytochrome c and Smac/DIABLO release.
    Kandasamy K, Srinivasula SM, Alnemri ES, Thompson CB, Korsmeyer SJ, Bryant JL, Srivastava RK.
    Cancer Res; 2003 Apr 01; 63(7):1712-21. PubMed ID: 12670926
    [Abstract] [Full Text] [Related]

  • 6. Caspase-2 triggers Bax-Bak-dependent and -independent cell death in colon cancer cells treated with resveratrol.
    Mohan J, Gandhi AA, Bhavya BC, Rashmi R, Karunagaran D, Indu R, Santhoshkumar TR.
    J Biol Chem; 2006 Jun 30; 281(26):17599-611. PubMed ID: 16617056
    [Abstract] [Full Text] [Related]

  • 7. Bax/Bak activation in the absence of Bid, Bim, Puma, and p53.
    Zhang J, Huang K, O'Neill KL, Pang X, Luo X.
    Cell Death Dis; 2016 Jun 16; 7(6):e2266. PubMed ID: 27310874
    [Abstract] [Full Text] [Related]

  • 8. A role for mitochondrial Bak in apoptotic response to anticancer drugs.
    Wang GQ, Gastman BR, Wieckowski E, Goldstein LA, Gambotto A, Kim TH, Fang B, Rabinovitz A, Yin XM, Rabinowich H.
    J Biol Chem; 2001 Sep 07; 276(36):34307-17. PubMed ID: 11447222
    [Abstract] [Full Text] [Related]

  • 9. Activation of mitochondrial protease OMA1 by Bax and Bak promotes cytochrome c release during apoptosis.
    Jiang X, Jiang H, Shen Z, Wang X.
    Proc Natl Acad Sci U S A; 2014 Oct 14; 111(41):14782-7. PubMed ID: 25275009
    [Abstract] [Full Text] [Related]

  • 10. BID preferentially activates BAK while BIM preferentially activates BAX, affecting chemotherapy response.
    Sarosiek KA, Chi X, Bachman JA, Sims JJ, Montero J, Patel L, Flanagan A, Andrews DW, Sorger P, Letai A.
    Mol Cell; 2013 Sep 26; 51(6):751-65. PubMed ID: 24074954
    [Abstract] [Full Text] [Related]

  • 11. VDAC2 is required for truncated BID-induced mitochondrial apoptosis by recruiting BAK to the mitochondria.
    Roy SS, Ehrlich AM, Craigen WJ, Hajnóczky G.
    EMBO Rep; 2009 Dec 26; 10(12):1341-7. PubMed ID: 19820692
    [Abstract] [Full Text] [Related]

  • 12. Apoptosis-inducing factor (AIF) is targeted in IFN-α2a-induced Bid-mediated apoptosis through Bak activation in ovarian cancer cells.
    Miyake K, Bekisz J, Zhao T, Clark CR, Zoon KC.
    Biochim Biophys Acta; 2012 Aug 26; 1823(8):1378-88. PubMed ID: 22683989
    [Abstract] [Full Text] [Related]

  • 13. Cleavage by Caspase 8 and Mitochondrial Membrane Association Activate the BH3-only Protein Bid during TRAIL-induced Apoptosis.
    Huang K, Zhang J, O'Neill KL, Gurumurthy CB, Quadros RM, Tu Y, Luo X.
    J Biol Chem; 2016 May 27; 291(22):11843-51. PubMed ID: 27053107
    [Abstract] [Full Text] [Related]

  • 14. BH3 domains other than Bim and Bid can directly activate Bax/Bak.
    Du H, Wolf J, Schafer B, Moldoveanu T, Chipuk JE, Kuwana T.
    J Biol Chem; 2011 Jan 07; 286(1):491-501. PubMed ID: 21041309
    [Abstract] [Full Text] [Related]

  • 15. Bax- or Bak-induced mitochondrial fission can be uncoupled from cytochrome C release.
    Sheridan C, Delivani P, Cullen SP, Martin SJ.
    Mol Cell; 2008 Aug 22; 31(4):570-585. PubMed ID: 18722181
    [Abstract] [Full Text] [Related]

  • 16. The BH3 alpha-helical mimic BH3-M6 disrupts Bcl-X(L), Bcl-2, and MCL-1 protein-protein interactions with Bax, Bak, Bad, or Bim and induces apoptosis in a Bax- and Bim-dependent manner.
    Kazi A, Sun J, Doi K, Sung SS, Takahashi Y, Yin H, Rodriguez JM, Becerril J, Berndt N, Hamilton AD, Wang HG, Sebti SM.
    J Biol Chem; 2011 Mar 18; 286(11):9382-92. PubMed ID: 21148306
    [Abstract] [Full Text] [Related]

  • 17. Bax-mediated mitochondrial outer membrane permeabilization (MOMP), distinct from the mitochondrial permeability transition, is a key mechanism in diclofenac-induced hepatocyte injury: Multiple protective roles of cyclosporin A.
    Siu WP, Pun PB, Latchoumycandane C, Boelsterli UA.
    Toxicol Appl Pharmacol; 2008 Mar 15; 227(3):451-61. PubMed ID: 18191430
    [Abstract] [Full Text] [Related]

  • 18. Bcl-2 family member Bfl-1/A1 sequesters truncated bid to inhibit is collaboration with pro-apoptotic Bak or Bax.
    Werner AB, de Vries E, Tait SW, Bontjer I, Borst J.
    J Biol Chem; 2002 Jun 21; 277(25):22781-8. PubMed ID: 11929871
    [Abstract] [Full Text] [Related]

  • 19. Stepwise activation of BAX and BAK by tBID, BIM, and PUMA initiates mitochondrial apoptosis.
    Kim H, Tu HC, Ren D, Takeuchi O, Jeffers JR, Zambetti GP, Hsieh JJ, Cheng EH.
    Mol Cell; 2009 Nov 13; 36(3):487-99. PubMed ID: 19917256
    [Abstract] [Full Text] [Related]

  • 20. Thrombin-triggered platelet apoptosis.
    Leytin V, Allen DJ, Mykhaylov S, Lyubimov E, Freedman J.
    J Thromb Haemost; 2006 Dec 13; 4(12):2656-63. PubMed ID: 16961585
    [Abstract] [Full Text] [Related]

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