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460 related items for PubMed ID: 18668558

  • 1. Rho-associated kinases are crucial for myofibroblast differentiation and production of extracellular matrix in scleroderma fibroblasts.
    Akhmetshina A, Dees C, Pileckyte M, Szucs G, Spriewald BM, Zwerina J, Distler O, Schett G, Distler JH.
    Arthritis Rheum; 2008 Aug; 58(8):2553-64. PubMed ID: 18668558
    [Abstract] [Full Text] [Related]

  • 2. Imatinib mesylate reduces production of extracellular matrix and prevents development of experimental dermal fibrosis.
    Distler JH, Jüngel A, Huber LC, Schulze-Horsel U, Zwerina J, Gay RE, Michel BA, Hauser T, Schett G, Gay S, Distler O.
    Arthritis Rheum; 2007 Jan; 56(1):311-22. PubMed ID: 17195235
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  • 3. Induction of the myofibroblastic phenotype in human gingival fibroblasts by transforming growth factor-beta1: role of RhoA-ROCK and c-Jun N-terminal kinase signaling pathways.
    Smith PC, Cáceres M, Martinez J.
    J Periodontal Res; 2006 Oct; 41(5):418-25. PubMed ID: 16953819
    [Abstract] [Full Text] [Related]

  • 4. The transcription factor Fra-2 regulates the production of extracellular matrix in systemic sclerosis.
    Reich N, Maurer B, Akhmetshina A, Venalis P, Dees C, Zerr P, Palumbo K, Zwerina J, Nevskaya T, Gay S, Distler O, Schett G, Distler JH.
    Arthritis Rheum; 2010 Jan; 62(1):280-90. PubMed ID: 20039427
    [Abstract] [Full Text] [Related]

  • 5. Src kinases in systemic sclerosis: central roles in fibroblast activation and in skin fibrosis.
    Skhirtladze C, Distler O, Dees C, Akhmetshina A, Busch N, Venalis P, Zwerina J, Spriewald B, Pileckyte M, Schett G, Distler JH.
    Arthritis Rheum; 2008 May; 58(5):1475-84. PubMed ID: 18438865
    [Abstract] [Full Text] [Related]

  • 6. Contractility as a prerequisite for TGF-beta-induced myofibroblast transdifferentiation in human tenon fibroblasts.
    Meyer-ter-Vehn T, Sieprath S, Katzenberger B, Gebhardt S, Grehn F, Schlunck G.
    Invest Ophthalmol Vis Sci; 2006 Nov; 47(11):4895-904. PubMed ID: 17065504
    [Abstract] [Full Text] [Related]

  • 7. Effect of simvastatin on transforming growth factor beta-1-induced myofibroblast differentiation and collagen production in nasal polyp-derived fibroblasts.
    Park IH, Park SJ, Cho JS, Moon YM, Moon JH, Kim TH, Lee SH, Lee HM.
    Am J Rhinol Allergy; 2012 Nov; 26(1):7-11. PubMed ID: 22391067
    [Abstract] [Full Text] [Related]

  • 8. Angiotensin II in the lesional skin of systemic sclerosis patients contributes to tissue fibrosis via angiotensin II type 1 receptors.
    Kawaguchi Y, Takagi K, Hara M, Fukasawa C, Sugiura T, Nishimagi E, Harigai M, Kamatani N.
    Arthritis Rheum; 2004 Jan; 50(1):216-26. PubMed ID: 14730619
    [Abstract] [Full Text] [Related]

  • 9. Rho/ROCK and MAPK signaling pathways are involved in glioblastoma cell migration and proliferation.
    Zohrabian VM, Forzani B, Chau Z, Murali R, Jhanwar-Uniyal M.
    Anticancer Res; 2009 Jan; 29(1):119-23. PubMed ID: 19331140
    [Abstract] [Full Text] [Related]

  • 10. Role of apoptosis and transforming growth factor beta1 in fibroblast selection and activation in systemic sclerosis.
    Jelaska A, Korn JH.
    Arthritis Rheum; 2000 Oct; 43(10):2230-9. PubMed ID: 11037882
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  • 13. Beneficial regulation of matrixmetalloproteinases and their inhibitors, fibrillar collagens and transforming growth factor-beta by Polypodium leucotomos, directly or in dermal fibroblasts, ultraviolet radiated fibroblasts, and melanoma cells.
    Philips N, Conte J, Chen YJ, Natrajan P, Taw M, Keller T, Givant J, Tuason M, Dulaj L, Leonardi D, Gonzalez S.
    Arch Dermatol Res; 2009 Aug; 301(7):487-95. PubMed ID: 19373483
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  • 15. Potential role of Rho-associated protein kinase inhibitor Y-27632 in glaucoma filtration surgery.
    Honjo M, Tanihara H, Kameda T, Kawaji T, Yoshimura N, Araie M.
    Invest Ophthalmol Vis Sci; 2007 Dec; 48(12):5549-57. PubMed ID: 18055804
    [Abstract] [Full Text] [Related]

  • 16. Increased levels of transforming growth factor beta receptor type I and up-regulation of matrix gene program: A model of scleroderma.
    Pannu J, Gardner H, Shearstone JR, Smith E, Trojanowska M.
    Arthritis Rheum; 2006 Sep; 54(9):3011-21. PubMed ID: 16947635
    [Abstract] [Full Text] [Related]

  • 17. Regulation of MT1-MMP and MMP-2 by leptin in cardiac fibroblasts involves Rho/ROCK-dependent actin cytoskeletal reorganization and leads to enhanced cell migration.
    Schram K, Ganguly R, No EK, Fang X, Thong FS, Sweeney G.
    Endocrinology; 2011 May; 152(5):2037-47. PubMed ID: 21385940
    [Abstract] [Full Text] [Related]

  • 18. Inhibition of activator protein 1 signaling abrogates transforming growth factor β-mediated activation of fibroblasts and prevents experimental fibrosis.
    Avouac J, Palumbo K, Tomcik M, Zerr P, Dees C, Horn A, Maurer B, Akhmetshina A, Beyer C, Sadowski A, Schneider H, Shiozawa S, Distler O, Schett G, Allanore Y, Distler JH.
    Arthritis Rheum; 2012 May; 64(5):1642-52. PubMed ID: 22139817
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  • 20. ROCK inhibition with Y27632 activates astrocytes and increases their expression of neurite growth-inhibitory chondroitin sulfate proteoglycans.
    Chan CC, Wong AK, Liu J, Steeves JD, Tetzlaff W.
    Glia; 2007 Mar; 55(4):369-84. PubMed ID: 17136770
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