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PUBMED FOR HANDHELDS

Journal Abstract Search


305 related items for PubMed ID: 18680316

  • 1. Enantioselective formation of ibuprofen-S-acyl-glutathione in vitro in incubations of ibuprofen with rat hepatocytes.
    Grillo MP, Hua F.
    Chem Res Toxicol; 2008 Sep; 21(9):1749-59. PubMed ID: 18680316
    [Abstract] [Full Text] [Related]

  • 2. Mechanistic studies on the bioactivation of diclofenac: identification of diclofenac-S-acyl-glutathione in vitro in incubations with rat and human hepatocytes.
    Grillo MP, Hua F, Knutson CG, Ware JA, Li C.
    Chem Res Toxicol; 2003 Nov; 16(11):1410-7. PubMed ID: 14615966
    [Abstract] [Full Text] [Related]

  • 3. Stereoselective flunoxaprofen-S-acyl-glutathione thioester formation mediated by acyl-CoA formation in rat hepatocytes.
    Grillo MP, Wait JC, Tadano Lohr M, Khera S, Benet LZ.
    Drug Metab Dispos; 2010 Jan; 38(1):133-42. PubMed ID: 19786506
    [Abstract] [Full Text] [Related]

  • 4. Identification of zomepirac-S-acyl-glutathione in vitro in incubations with rat hepatocytes and in vivo in rat bile.
    Grillo MP, Hua F.
    Drug Metab Dispos; 2003 Nov; 31(11):1429-36. PubMed ID: 14570776
    [Abstract] [Full Text] [Related]

  • 5. Metabolic activation of mefenamic acid leading to mefenamyl-S-acyl-glutathione adduct formation in vitro and in vivo in rat.
    Grillo MP, Tadano Lohr M, Wait JC.
    Drug Metab Dispos; 2012 Aug; 40(8):1515-26. PubMed ID: 22577085
    [Abstract] [Full Text] [Related]

  • 6. Interaction of γ-glutamyltranspeptidase with ibuprofen-S-acyl-glutathione in vitro and in vivo in human.
    Grillo MP, Lohr MT, Khera S.
    Drug Metab Dispos; 2013 Jan; 41(1):111-21. PubMed ID: 23052971
    [Abstract] [Full Text] [Related]

  • 7. Covalent binding of phenylacetic acid to protein in incubations with freshly isolated rat hepatocytes.
    Grillo MP, Lohr MT.
    Drug Metab Dispos; 2009 May; 37(5):1073-82. PubMed ID: 19196839
    [Abstract] [Full Text] [Related]

  • 8. Modulation of enantioselective metabolism and inversion of ibuprofen by xenobiotics in isolated rat hepatocytes.
    Xiaotao Q, Hall SD.
    J Pharmacol Exp Ther; 1993 Aug; 266(2):845-51. PubMed ID: 8355212
    [Abstract] [Full Text] [Related]

  • 9. Gamma-glutamyltranspeptidase-mediated degradation of diclofenac-S-acyl-glutathione in vitro and in vivo in rat.
    Grillo MP, Hua F, March KL, Benet LZ, Knutson CG, Ware JA.
    Chem Res Toxicol; 2008 Oct; 21(10):1933-8. PubMed ID: 18693772
    [Abstract] [Full Text] [Related]

  • 10. A novel bioactivation pathway for 2-[2-(2,6-dichlorophenyl)aminophenyl]ethanoic acid (diclofenac) initiated by cytochrome P450-mediated oxidative decarboxylation.
    Grillo MP, Ma J, Teffera Y, Waldon DJ.
    Drug Metab Dispos; 2008 Sep; 36(9):1740-4. PubMed ID: 18541695
    [Abstract] [Full Text] [Related]

  • 11. Characterization of the acyl-adenylate linked metabolite of mefenamic Acid.
    Horng H, Benet LZ.
    Chem Res Toxicol; 2013 Mar 18; 26(3):465-76. PubMed ID: 23402341
    [Abstract] [Full Text] [Related]

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  • 14. Metabolic inversion of (R)-ibuprofen. Formation of ibuprofenyl-coenzyme A.
    Tracy TS, Wirthwein DP, Hall SD.
    Drug Metab Dispos; 1993 Mar 18; 21(1):114-20. PubMed ID: 8095203
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  • 17. Evidence for the bioactivation of zomepirac and tolmetin by an oxidative pathway: identification of glutathione adducts in vitro in human liver microsomes and in vivo in rats.
    Chen Q, Doss GA, Tung EC, Liu W, Tang YS, Braun MP, Didolkar V, Strauss JR, Wang RW, Stearns RA, Evans DC, Baillie TA, Tang W.
    Drug Metab Dispos; 2006 Jan 18; 34(1):145-51. PubMed ID: 16251255
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  • 19. Studies on the reactivity of clofibryl-S-acyl-CoA thioester with glutathione in vitro.
    Grillo MP, Benet LZ.
    Drug Metab Dispos; 2002 Jan 18; 30(1):55-62. PubMed ID: 11744612
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