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282 related items for PubMed ID: 18690053

  • 1. Mutations within the agonist-binding site convert the homomeric alpha1 glycine receptor into a Zn2+-activated chloride channel.
    Grudzinska J, Schumann T, Schemm R, Betz H, Laube B.
    Channels (Austin); 2008; 2(1):13-8. PubMed ID: 18690053
    [Abstract] [Full Text] [Related]

  • 2. Identification of an inhibitory Zn2+ binding site on the human glycine receptor alpha1 subunit.
    Harvey RJ, Thomas P, James CH, Wilderspin A, Smart TG.
    J Physiol; 1999 Oct 01; 520 Pt 1(Pt 1):53-64. PubMed ID: 10517800
    [Abstract] [Full Text] [Related]

  • 3. Kinetic and mutational analysis of Zn2+ modulation of recombinant human inhibitory glycine receptors.
    Laube B, Kuhse J, Betz H.
    J Physiol; 2000 Jan 15; 522 Pt 2(Pt 2):215-30. PubMed ID: 10639099
    [Abstract] [Full Text] [Related]

  • 4. Binding-site mutations in the alpha1 subunit of the inhibitory glycine receptor convert the inhibitory metal ion Cu2+ into a positive modulator.
    Schumann T, Grudzinska J, Kuzmin D, Betz H, Laube B.
    Neuropharmacology; 2009 Jan 15; 56(1):310-7. PubMed ID: 18793654
    [Abstract] [Full Text] [Related]

  • 5. Modulation by zinc ions of native rat and recombinant human inhibitory glycine receptors.
    Laube B, Kuhse J, Rundström N, Kirsch J, Schmieden V, Betz H.
    J Physiol; 1995 Mar 15; 483 ( Pt 3)(Pt 3):613-9. PubMed ID: 7776247
    [Abstract] [Full Text] [Related]

  • 6. Characterization of two mutations, M287L and Q266I, in the α1 glycine receptor subunit that modify sensitivity to alcohols.
    Borghese CM, Blednov YA, Quan Y, Iyer SV, Xiong W, Mihic SJ, Zhang L, Lovinger DM, Trudell JR, Homanics GE, Harris RA.
    J Pharmacol Exp Ther; 2012 Feb 15; 340(2):304-16. PubMed ID: 22037201
    [Abstract] [Full Text] [Related]

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  • 8. Probing the pharmacological properties of distinct subunit interfaces within heteromeric glycine receptors reveals a functional ββ agonist-binding site.
    Dutertre S, Drwal M, Laube B, Betz H.
    J Neurochem; 2012 Jul 15; 122(1):38-47. PubMed ID: 22486198
    [Abstract] [Full Text] [Related]

  • 9. Different binding modes of tropeines mediating inhibition and potentiation of alpha1 glycine receptors.
    Maksay G, Laube B, Schemm R, Grudzinska J, Drwal M, Betz H.
    J Neurochem; 2009 Jun 15; 109(6):1725-32. PubMed ID: 19383091
    [Abstract] [Full Text] [Related]

  • 10. Pharmacological characterization of glycine-gated chloride currents recorded in rat hippocampal slices.
    Chattipakorn SC, McMahon LL.
    J Neurophysiol; 2002 Mar 15; 87(3):1515-25. PubMed ID: 11877523
    [Abstract] [Full Text] [Related]

  • 11. Structure and functions of inhibitory and excitatory glycine receptors.
    Betz H, Kuhse J, Schmieden V, Laube B, Kirsch J, Harvey RJ.
    Ann N Y Acad Sci; 1999 Apr 30; 868():667-76. PubMed ID: 10414351
    [Abstract] [Full Text] [Related]

  • 12. Ethanol potentiation of glycine receptors expressed in Xenopus oocytes antagonized by increased atmospheric pressure.
    Davies DL, Trudell JR, Mihic SJ, Crawford DK, Alkana RL.
    Alcohol Clin Exp Res; 2003 May 30; 27(5):743-55. PubMed ID: 12766618
    [Abstract] [Full Text] [Related]

  • 13. Zinc potentiation of the glycine receptor chloride channel is mediated by allosteric pathways.
    Lynch JW, Jacques P, Pierce KD, Schofield PR.
    J Neurochem; 1998 Nov 30; 71(5):2159-68. PubMed ID: 9798943
    [Abstract] [Full Text] [Related]

  • 14. The extracellular disulfide loop motif of the inhibitory glycine receptor does not form the agonist binding site.
    Vandenberg RJ, Rajendra S, French CR, Barry PH, Schofield PR.
    Mol Pharmacol; 1993 Jul 30; 44(1):198-203. PubMed ID: 8393521
    [Abstract] [Full Text] [Related]

  • 15. Ivermectin, an unconventional agonist of the glycine receptor chloride channel.
    Shan Q, Haddrill JL, Lynch JW.
    J Biol Chem; 2001 Apr 20; 276(16):12556-64. PubMed ID: 11278873
    [Abstract] [Full Text] [Related]

  • 16. Cation-selective mutations in the M2 domain of the inhibitory glycine receptor channel reveal determinants of ion-charge selectivity.
    Keramidas A, Moorhouse AJ, Pierce KD, Schofield PR, Barry PH.
    J Gen Physiol; 2002 May 20; 119(5):393-410. PubMed ID: 11981020
    [Abstract] [Full Text] [Related]

  • 17. Agonist pharmacology of neonatal and adult glycine receptor alpha subunits: identification of amino acid residues involved in taurine activation.
    Schmieden V, Kuhse J, Betz H.
    EMBO J; 1992 Jun 20; 11(6):2025-32. PubMed ID: 1376243
    [Abstract] [Full Text] [Related]

  • 18. Startle disease mutations reduce the agonist sensitivity of the human inhibitory glycine receptor.
    Rajendra S, Lynch JW, Pierce KD, French CR, Barry PH, Schofield PR.
    J Biol Chem; 1994 Jul 22; 269(29):18739-42. PubMed ID: 7518444
    [Abstract] [Full Text] [Related]

  • 19. The interaction of general anaesthetics with recombinant GABAA and glycine receptors expressed in Xenopus laevis oocytes: a comparative study.
    Pistis M, Belelli D, Peters JA, Lambert JJ.
    Br J Pharmacol; 1997 Dec 22; 122(8):1707-19. PubMed ID: 9422818
    [Abstract] [Full Text] [Related]

  • 20. Roles for loop 2 residues of alpha1 glycine receptors in agonist activation.
    Crawford DK, Perkins DI, Trudell JR, Bertaccini EJ, Davies DL, Alkana RL.
    J Biol Chem; 2008 Oct 10; 283(41):27698-27706. PubMed ID: 18658152
    [Abstract] [Full Text] [Related]

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