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294 related items for PubMed ID: 18691182

  • 1. Partial proteasome inhibition in human fibroblasts triggers accelerated M1 senescence or M2 crisis depending on p53 and Rb status.
    Chondrogianni N, Trougakos IP, Kletsas D, Chen QM, Gonos ES.
    Aging Cell; 2008 Oct; 7(5):717-32. PubMed ID: 18691182
    [Abstract] [Full Text] [Related]

  • 2. Sequential extension of proliferative lifespan in human fibroblasts induced by over-expression of CDK4 or 6 and loss of p53 function.
    Morris M, Hepburn P, Wynford-Thomas D.
    Oncogene; 2002 Jun 20; 21(27):4277-88. PubMed ID: 12082615
    [Abstract] [Full Text] [Related]

  • 3. Reexpression of the retinoblastoma protein in tumor cells induces senescence and telomerase inhibition.
    Xu HJ, Zhou Y, Ji W, Perng GS, Kruzelock R, Kong CT, Bast RC, Mills GB, Li J, Hu SX.
    Oncogene; 1997 Nov 20; 15(21):2589-96. PubMed ID: 9399646
    [Abstract] [Full Text] [Related]

  • 4. Histone deacetylase inhibitors induce a senescence-like state in human cells by a p16-dependent mechanism that is independent of a mitotic clock.
    Munro J, Barr NI, Ireland H, Morrison V, Parkinson EK.
    Exp Cell Res; 2004 May 01; 295(2):525-38. PubMed ID: 15093749
    [Abstract] [Full Text] [Related]

  • 5. P53-Rb signaling pathway is involved in tubular cell senescence in renal ischemia/reperfusion injury.
    Kailong L, Du X, Yani H, Lin Z, Jvrong Y, Ruihua S, Lin C.
    Biocell; 2007 Aug 01; 31(2):213-23. PubMed ID: 17902269
    [Abstract] [Full Text] [Related]

  • 6. Escape from premature senescence is not sufficient for oncogenic transformation by Ras.
    Peeper DS, Dannenberg JH, Douma S, te Riele H, Bernards R.
    Nat Cell Biol; 2001 Feb 01; 3(2):198-203. PubMed ID: 11175753
    [Abstract] [Full Text] [Related]

  • 7. p53 is preferentially recruited to the promoters of growth arrest genes p21 and GADD45 during replicative senescence of normal human fibroblasts.
    Jackson JG, Pereira-Smith OM.
    Cancer Res; 2006 Sep 01; 66(17):8356-60. PubMed ID: 16951143
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  • 10. Proteasome inhibitors shorten replicative life span and induce a senescent-like phenotype of human fibroblasts.
    Torres C, Lewis L, Cristofalo VJ.
    J Cell Physiol; 2006 Jun 01; 207(3):845-53. PubMed ID: 16523493
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  • 11. p53-related apoptosis resistance and tumor suppression activity in UVB-induced premature senescent human skin fibroblasts.
    Chen W, Kang J, Xia J, Li Y, Yang B, Chen B, Sun W, Song X, Xiang W, Wang X, Wang F, Wan Y, Bi Z.
    Int J Mol Med; 2008 May 01; 21(5):645-53. PubMed ID: 18425358
    [Abstract] [Full Text] [Related]

  • 12. Repeated exposure of human skin fibroblasts to UVB at subcytotoxic level triggers premature senescence through the TGF-beta1 signaling pathway.
    Debacq-Chainiaux F, Borlon C, Pascal T, Royer V, Eliaers F, Ninane N, Carrard G, Friguet B, de Longueville F, Boffe S, Remacle J, Toussaint O.
    J Cell Sci; 2005 Feb 15; 118(Pt 4):743-58. PubMed ID: 15671065
    [Abstract] [Full Text] [Related]

  • 13. Evidence that transcriptional activation by p53 plays a direct role in the induction of cellular senescence.
    Bond J, Haughton M, Blaydes J, Gire V, Wynford-Thomas D, Wyllie F.
    Oncogene; 1996 Nov 21; 13(10):2097-104. PubMed ID: 8950976
    [Abstract] [Full Text] [Related]

  • 14. The ability of E1A to rescue ras-induced premature senescence and confer transformation relies on inactivation of both p300/CBP and Rb family proteins.
    Deng Q, Li Y, Tedesco D, Liao R, Fuhrmann G, Sun P.
    Cancer Res; 2005 Sep 15; 65(18):8298-307. PubMed ID: 16166306
    [Abstract] [Full Text] [Related]

  • 15. Proteasome response to interferon-gamma is altered in senescent human fibroblasts.
    Stratford FL, Chondrogianni N, Trougakos IP, Gonos ES, Rivett AJ.
    FEBS Lett; 2006 Jul 10; 580(16):3989-94. PubMed ID: 16806194
    [Abstract] [Full Text] [Related]

  • 16. Suppression of thioredoxin-1 induces premature senescence in normal human fibroblasts.
    Young JJ, Patel A, Rai P.
    Biochem Biophys Res Commun; 2010 Feb 12; 392(3):363-8. PubMed ID: 20074557
    [Abstract] [Full Text] [Related]

  • 17. Age-dependent response of primary human dermal fibroblasts to oxidative stress: cell survival, pro-survival kinases, and entrance into cellular senescence.
    Gurjala AN, Liu WR, Mogford JE, Procaccini PS, Mustoe TA.
    Wound Repair Regen; 2005 Feb 12; 13(6):565-75. PubMed ID: 16283872
    [Abstract] [Full Text] [Related]

  • 18. Effects of donor age on proteasome activity and senescence in trabecular meshwork cells.
    Caballero M, Liton PB, Challa P, Epstein DL, Gonzalez P.
    Biochem Biophys Res Commun; 2004 Oct 22; 323(3):1048-54. PubMed ID: 15381105
    [Abstract] [Full Text] [Related]

  • 19. Human fibroblasts require the Rb family of tumor suppressors, but not p53, for PML-induced senescence.
    Mallette FA, Goumard S, Gaumont-Leclerc MF, Moiseeva O, Ferbeyre G.
    Oncogene; 2004 Jan 08; 23(1):91-9. PubMed ID: 14712214
    [Abstract] [Full Text] [Related]

  • 20. Human dermal fibroblasts escape from the long-term phenocopy of senescence induced by psoralen photoactivation.
    Ma W, Wlaschek M, Brenneisen P, Schneider LA, Hommel C, Hellweg C, Sauer H, Wartenberg M, Herrmann G, Meewes C, Boukamp P, Scharffetter-Kochanek K.
    Exp Cell Res; 2002 Apr 01; 274(2):299-309. PubMed ID: 11900490
    [Abstract] [Full Text] [Related]

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