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172 related items for PubMed ID: 18696333

  • 1. Oridonin induces human melanoma A375-S2 cell death partially through inhibiting insulin-like growth factor 1 receptor signaling.
    Wang HJ, Li D, Yang FY, Tashiro S, Onodera S, Ikejima T.
    J Asian Nat Prod Res; 2008; 10(7-8):787-98. PubMed ID: 18696333
    [Abstract] [Full Text] [Related]

  • 2. Oridonin induced A375-S2 cell apoptosis via bax-regulated caspase pathway activation, dependent on the cytochrome c/caspase-9 apoptosome.
    Zhang CL, Wu LJ, Tashiro S, Onodera S, Ikejima T.
    J Asian Nat Prod Res; 2004 Jun; 6(2):127-38. PubMed ID: 15008459
    [Abstract] [Full Text] [Related]

  • 3. Aberrant expression and activation of insulin-like growth factor-1 receptor (IGF-1R) are mediated by an induction of IGF-1R promoter activity and stabilization of IGF-1R mRNA and contributes to growth factor independence and increased survival of the pancreatic cancer cell line MIA PaCa-2.
    Nair PN, De Armond DT, Adamo ML, Strodel WE, Freeman JW.
    Oncogene; 2001 Dec 13; 20(57):8203-14. PubMed ID: 11781836
    [Abstract] [Full Text] [Related]

  • 4. Interruption of mitochondrial complex IV activity and cytochrome c expression activated O₂·⁻-mediated cell survival in silibinin-treated human melanoma A375-S2 cells via IGF-1R-PI3K-Akt and IGF-1R-PLC γ-PKC pathways.
    Jiang YY, Huang H, Wang HJ, Wu D, Yang R, Tashiro S, Onodera S, Ikejima T.
    Eur J Pharmacol; 2011 Oct 01; 668(1-2):78-87. PubMed ID: 21703257
    [Abstract] [Full Text] [Related]

  • 5. Oridonin induces G2/M arrest and apoptosis via activating ERK-p53 apoptotic pathway and inhibiting PTK-Ras-Raf-JNK survival pathway in murine fibrosarcoma L929 cells.
    Cheng Y, Qiu F, Ye YC, Tashiro S, Onodera S, Ikejima T.
    Arch Biochem Biophys; 2009 Oct 01; 490(1):70-5. PubMed ID: 19699177
    [Abstract] [Full Text] [Related]

  • 6. Insulin-like growth factor type-I receptor-dependent phosphorylation of extracellular signal-regulated kinase 1/2 but not Akt (protein kinase B) can be induced by picropodophyllin.
    Vasilcanu R, Vasilcanu D, Sehat B, Yin S, Girnita A, Axelson M, Girnita L.
    Mol Pharmacol; 2008 Mar 01; 73(3):930-9. PubMed ID: 18070930
    [Abstract] [Full Text] [Related]

  • 7. Autophagy inhibits reactive oxygen species-mediated apoptosis via activating p38-nuclear factor-kappa B survival pathways in oridonin-treated murine fibrosarcoma L929 cells.
    Cheng Y, Qiu F, Ye YC, Guo ZM, Tashiro S, Onodera S, Ikejima T.
    FEBS J; 2009 Mar 01; 276(5):1291-306. PubMed ID: 19187231
    [Abstract] [Full Text] [Related]

  • 8. Oridonin induces apoptosis via PI3K/Akt pathway in cervical carcinoma HeLa cell line.
    Hu HZ, Yang YB, Xu XD, Shen HW, Shu YM, Ren Z, Li XM, Shen HM, Zeng HT.
    Acta Pharmacol Sin; 2007 Nov 01; 28(11):1819-26. PubMed ID: 17959034
    [Abstract] [Full Text] [Related]

  • 9. Oridonin induces human epidermoid carcinoma A431 cell apoptosis through tyrosine kinase and mitochondrial pathway.
    Li D, Wu LJ, Tashiro S, Onodera S, Ikejima T.
    J Asian Nat Prod Res; 2008 Nov 01; 10(1-2):77-87. PubMed ID: 18058384
    [Abstract] [Full Text] [Related]

  • 10. The cytostatic and cytotoxic effects of oridonin (Rubescenin), a diterpenoid from Rabdosia rubescens, on tumor cells of different lineage.
    Chen S, Gao J, Halicka HD, Huang X, Traganos F, Darzynkiewicz Z.
    Int J Oncol; 2005 Mar 01; 26(3):579-88. PubMed ID: 15703811
    [Abstract] [Full Text] [Related]

  • 11. RaLP, a new member of the Src homology and collagen family, regulates cell migration and tumor growth of metastatic melanomas.
    Fagiani E, Giardina G, Luzi L, Cesaroni M, Quarto M, Capra M, Germano G, Bono M, Capillo M, Pelicci P, Lanfrancone L.
    Cancer Res; 2007 Apr 01; 67(7):3064-73. PubMed ID: 17409413
    [Abstract] [Full Text] [Related]

  • 12. Nucleotide excision repair is not required for the antiapoptotic function of insulin-like growth factor 1.
    Lee-Kwon W, Park D, Bernier M.
    Exp Cell Res; 1998 Jun 15; 241(2):458-66. PubMed ID: 9637787
    [Abstract] [Full Text] [Related]

  • 13. Activation of p38 mitogen-activated protein kinase is required for death receptor-independent caspase-8 activation and cell death in response to sphingosine.
    Yoon CH, Kim MJ, Park MT, Byun JY, Choi YH, Yoo HS, Lee YM, Hyun JW, Lee SJ.
    Mol Cancer Res; 2009 Mar 15; 7(3):361-70. PubMed ID: 19276187
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  • 16. Insulin-like growth factor 1 receptor signaling regulates skin development and inhibits skin keratinocyte differentiation.
    Sadagurski M, Yakar S, Weingarten G, Holzenberger M, Rhodes CJ, Breitkreutz D, Leroith D, Wertheimer E.
    Mol Cell Biol; 2006 Apr 15; 26(7):2675-87. PubMed ID: 16537911
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  • 20. Insulin-like growth factor-I receptor signal transduction and the Janus Kinase/Signal Transducer and Activator of Transcription (JAK-STAT) pathway.
    Himpe E, Kooijman R.
    Biofactors; 2009 Apr 15; 35(1):76-81. PubMed ID: 19319849
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