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Journal Abstract Search


1140 related items for PubMed ID: 18706424

  • 1. Increased folding stability of TEM-1 beta-lactamase by in vitro selection.
    Kather I, Jakob RP, Dobbek H, Schmid FX.
    J Mol Biol; 2008 Oct 31; 383(1):238-51. PubMed ID: 18706424
    [Abstract] [Full Text] [Related]

  • 2. Stabilization of the cold shock protein CspB from Bacillus subtilis by evolutionary optimization of Coulombic interactions.
    Wunderlich M, Martin A, Schmid FX.
    J Mol Biol; 2005 Apr 15; 347(5):1063-76. PubMed ID: 15784264
    [Abstract] [Full Text] [Related]

  • 3. In-vitro selection of highly stabilized protein variants with optimized surface.
    Martin A, Sieber V, Schmid FX.
    J Mol Biol; 2001 Jun 08; 309(3):717-26. PubMed ID: 11397091
    [Abstract] [Full Text] [Related]

  • 4. A stable disulfide-free gene-3-protein of phage fd generated by in vitro evolution.
    Kather I, Bippes CA, Schmid FX.
    J Mol Biol; 2005 Dec 02; 354(3):666-78. PubMed ID: 16259997
    [Abstract] [Full Text] [Related]

  • 5. In vitro evolution of a hyperstable Gbeta1 variant.
    Wunderlich M, Schmid FX.
    J Mol Biol; 2006 Oct 20; 363(2):545-57. PubMed ID: 16978647
    [Abstract] [Full Text] [Related]

  • 6. Competition between DsbA-mediated oxidation and conformational folding of RTEM1 beta-lactamase.
    Frech C, Wunderlich M, Glockshuber R, Schmid FX.
    Biochemistry; 1996 Sep 03; 35(35):11386-95. PubMed ID: 8784194
    [Abstract] [Full Text] [Related]

  • 7. Structural perturbation and compensation by directed evolution at physiological temperature leads to thermostabilization of beta-lactamase.
    Hecky J, Müller KM.
    Biochemistry; 2005 Sep 27; 44(38):12640-54. PubMed ID: 16171379
    [Abstract] [Full Text] [Related]

  • 8. X-ray structure of the Asn276Asp variant of the Escherichia coli TEM-1 beta-lactamase: direct observation of electrostatic modulation in resistance to inactivation by clavulanic acid.
    Swarén P, Golemi D, Cabantous S, Bulychev A, Maveyraud L, Mobashery S, Samama JP.
    Biochemistry; 1999 Jul 27; 38(30):9570-6. PubMed ID: 10423234
    [Abstract] [Full Text] [Related]

  • 9. Predicting the emergence of antibiotic resistance by directed evolution and structural analysis.
    Orencia MC, Yoon JS, Ness JE, Stemmer WP, Stevens RC.
    Nat Struct Biol; 2001 Mar 27; 8(3):238-42. PubMed ID: 11224569
    [Abstract] [Full Text] [Related]

  • 10. Exploring the molecular linkage of protein stability traits for enzyme optimization by iterative truncation and evolution.
    Speck J, Hecky J, Tam HK, Arndt KM, Einsle O, Müller KM.
    Biochemistry; 2012 Jun 19; 51(24):4850-67. PubMed ID: 22545913
    [Abstract] [Full Text] [Related]

  • 11. Intense neutral drifts yield robust and evolvable consensus proteins.
    Bershtein S, Goldin K, Tawfik DS.
    J Mol Biol; 2008 Jun 20; 379(5):1029-44. PubMed ID: 18495157
    [Abstract] [Full Text] [Related]

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  • 13. Evolutionary protein stabilization in comparison with computational design.
    Wunderlich M, Martin A, Staab CA, Schmid FX.
    J Mol Biol; 2005 Sep 02; 351(5):1160-8. PubMed ID: 16051264
    [Abstract] [Full Text] [Related]

  • 14. Optimized variants of the cold shock protein from in vitro selection: structural basis of their high thermostability.
    Max KE, Wunderlich M, Roske Y, Schmid FX, Heinemann U.
    J Mol Biol; 2007 Jun 15; 369(4):1087-97. PubMed ID: 17481655
    [Abstract] [Full Text] [Related]

  • 15. Natural selection for kinetic stability is a likely origin of correlations between mutational effects on protein energetics and frequencies of amino acid occurrences in sequence alignments.
    Godoy-Ruiz R, Ariza F, Rodriguez-Larrea D, Perez-Jimenez R, Ibarra-Molero B, Sanchez-Ruiz JM.
    J Mol Biol; 2006 Oct 06; 362(5):966-78. PubMed ID: 16935299
    [Abstract] [Full Text] [Related]

  • 16. Functional analyses of AmpC beta-lactamase through differential stability.
    Beadle BM, McGovern SL, Patera A, Shoichet BK.
    Protein Sci; 1999 Sep 06; 8(9):1816-24. PubMed ID: 10493583
    [Abstract] [Full Text] [Related]

  • 17. Atomic resolution structures of CTX-M beta-lactamases: extended spectrum activities from increased mobility and decreased stability.
    Chen Y, Delmas J, Sirot J, Shoichet B, Bonnet R.
    J Mol Biol; 2005 Apr 29; 348(2):349-62. PubMed ID: 15811373
    [Abstract] [Full Text] [Related]

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  • 19. Changing the determinants of protein stability from covalent to non-covalent interactions by in vitro evolution: a structural and energetic analysis.
    Kather I, Jakob R, Dobbek H, Schmid FX.
    J Mol Biol; 2008 Sep 12; 381(4):1040-54. PubMed ID: 18621056
    [Abstract] [Full Text] [Related]

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