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322 related items for PubMed ID: 18710949

  • 1. Phosphorylation of p27Kip1 regulates assembly and activation of cyclin D1-Cdk4.
    Larrea MD, Liang J, Da Silva T, Hong F, Shao SH, Han K, Dumont D, Slingerland JM.
    Mol Cell Biol; 2008 Oct; 28(20):6462-72. PubMed ID: 18710949
    [Abstract] [Full Text] [Related]

  • 2. ErbB2/neu kinase modulates cellular p27(Kip1) and cyclin D1 through multiple signaling pathways.
    Lenferink AE, Busse D, Flanagan WM, Yakes FM, Arteaga CL.
    Cancer Res; 2001 Sep 01; 61(17):6583-91. PubMed ID: 11522658
    [Abstract] [Full Text] [Related]

  • 3. p27Kip1 inhibits cyclin D-cyclin-dependent kinase 4 by two independent modes.
    Ray A, James MK, Larochelle S, Fisher RP, Blain SW.
    Mol Cell Biol; 2009 Feb 01; 29(4):986-99. PubMed ID: 19075005
    [Abstract] [Full Text] [Related]

  • 4. Incomplete folding upon binding mediates Cdk4/cyclin D complex activation by tyrosine phosphorylation of inhibitor p27 protein.
    Ou L, Ferreira AM, Otieno S, Xiao L, Bashford D, Kriwacki RW.
    J Biol Chem; 2011 Aug 26; 286(34):30142-51. PubMed ID: 21715330
    [Abstract] [Full Text] [Related]

  • 5. Dual Inhibition of CDK4 and CDK2 via Targeting p27 Tyrosine Phosphorylation Induces a Potent and Durable Response in Breast Cancer Cells.
    Patel P, Tsiperson V, Gottesman SRS, Somma J, Blain SW.
    Mol Cancer Res; 2018 Mar 26; 16(3):361-377. PubMed ID: 29330290
    [Abstract] [Full Text] [Related]

  • 6. Estrogen-induced activation of Cdk4 and Cdk2 during G1-S phase progression is accompanied by increased cyclin D1 expression and decreased cyclin-dependent kinase inhibitor association with cyclin E-Cdk2.
    Prall OW, Sarcevic B, Musgrove EA, Watts CK, Sutherland RL.
    J Biol Chem; 1997 Apr 18; 272(16):10882-94. PubMed ID: 9099745
    [Abstract] [Full Text] [Related]

  • 7. Regulation of G(1) cyclin-dependent kinases in the liver: role of nuclear localization and p27 sequestration.
    Albrecht JH, Rieland BM, Nelsen CJ, Ahonen CL.
    Am J Physiol; 1999 Dec 18; 277(6):G1207-16. PubMed ID: 10600818
    [Abstract] [Full Text] [Related]

  • 8. Assembly of cyclin D-dependent kinase and titration of p27Kip1 regulated by mitogen-activated protein kinase kinase (MEK1).
    Cheng M, Sexl V, Sherr CJ, Roussel MF.
    Proc Natl Acad Sci U S A; 1998 Feb 03; 95(3):1091-6. PubMed ID: 9448290
    [Abstract] [Full Text] [Related]

  • 9. The proto-oncogene c-myc acts through the cyclin-dependent kinase (Cdk) inhibitor p27(Kip1) to facilitate the activation of Cdk4/6 and early G(1) phase progression.
    Obaya AJ, Kotenko I, Cole MD, Sedivy JM.
    J Biol Chem; 2002 Aug 23; 277(34):31263-9. PubMed ID: 12070150
    [Abstract] [Full Text] [Related]

  • 10. Akt-dependent T198 phosphorylation of cyclin-dependent kinase inhibitor p27kip1 in breast cancer.
    Motti ML, De Marco C, Califano D, Fusco A, Viglietto G.
    Cell Cycle; 2004 Aug 23; 3(8):1074-80. PubMed ID: 15280662
    [Abstract] [Full Text] [Related]

  • 11. Altered p27(Kip1) phosphorylation, localization, and function in human epithelial cells resistant to transforming growth factor beta-mediated G(1) arrest.
    Ciarallo S, Subramaniam V, Hung W, Lee JH, Kotchetkov R, Sandhu C, Milic A, Slingerland JM.
    Mol Cell Biol; 2002 May 23; 22(9):2993-3002. PubMed ID: 11940657
    [Abstract] [Full Text] [Related]

  • 12. p27 phosphorylation by Src regulates inhibition of cyclin E-Cdk2.
    Chu I, Sun J, Arnaout A, Kahn H, Hanna W, Narod S, Sun P, Tan CK, Hengst L, Slingerland J.
    Cell; 2007 Jan 26; 128(2):281-94. PubMed ID: 17254967
    [Abstract] [Full Text] [Related]

  • 13. Cell cycle exit during terminal erythroid differentiation is associated with accumulation of p27(Kip1) and inactivation of cdk2 kinase.
    Hsieh FF, Barnett LA, Green WF, Freedman K, Matushansky I, Skoultchi AI, Kelley LL.
    Blood; 2000 Oct 15; 96(8):2746-54. PubMed ID: 11023508
    [Abstract] [Full Text] [Related]

  • 14. RSK1 drives p27Kip1 phosphorylation at T198 to promote RhoA inhibition and increase cell motility.
    Larrea MD, Hong F, Wander SA, da Silva TG, Helfman D, Lannigan D, Smith JA, Slingerland JM.
    Proc Natl Acad Sci U S A; 2009 Jun 09; 106(23):9268-73. PubMed ID: 19470470
    [Abstract] [Full Text] [Related]

  • 15. p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21.
    Toyoshima H, Hunter T.
    Cell; 1994 Jul 15; 78(1):67-74. PubMed ID: 8033213
    [Abstract] [Full Text] [Related]

  • 16. New functional activities for the p21 family of CDK inhibitors.
    LaBaer J, Garrett MD, Stevenson LF, Slingerland JM, Sandhu C, Chou HS, Fattaey A, Harlow E.
    Genes Dev; 1997 Apr 01; 11(7):847-62. PubMed ID: 9106657
    [Abstract] [Full Text] [Related]

  • 17. Kip/Cip and Ink4 Cdk inhibitors cooperate to induce cell cycle arrest in response to TGF-beta.
    Reynisdóttir I, Polyak K, Iavarone A, Massagué J.
    Genes Dev; 1995 Aug 01; 9(15):1831-45. PubMed ID: 7649471
    [Abstract] [Full Text] [Related]

  • 18. p27kip1 Regulates cdk2 activity in the proliferating zone of the mouse intestinal epithelium: potential role in neoplasia.
    Smartt HJ, Guilmeau S, Nasser SV, Nicholas C, Bancroft L, Simpson SA, Yeh N, Yang W, Mariadason JM, Koff A, Augenlicht LH.
    Gastroenterology; 2007 Jul 01; 133(1):232-43. PubMed ID: 17631145
    [Abstract] [Full Text] [Related]

  • 19. Cyclic AMP-dependent phosphorylation of cyclin D3-bound CDK4 determines the passage through the cell cycle restriction point in thyroid epithelial cells.
    Paternot S, Coulonval K, Dumont JE, Roger PP.
    J Biol Chem; 2003 Jul 18; 278(29):26533-40. PubMed ID: 12730225
    [Abstract] [Full Text] [Related]

  • 20. p27 allosterically activates cyclin-dependent kinase 4 and antagonizes palbociclib inhibition.
    Guiley KZ, Stevenson JW, Lou K, Barkovich KJ, Kumarasamy V, Wijeratne TU, Bunch KL, Tripathi S, Knudsen ES, Witkiewicz AK, Shokat KM, Rubin SM.
    Science; 2019 Dec 13; 366(6471):. PubMed ID: 31831640
    [Abstract] [Full Text] [Related]

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