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1143 related items for PubMed ID: 18712569

  • 1. Association of O6-methylguanine-DNA methyltransferase (MGMT) promoter methylation with p53 mutation occurrence in non-small cell lung cancer with different histology, gender, and smoking status.
    Wu JY, Wang J, Lai JC, Cheng YW, Yeh KT, Wu TC, Chen CY, Lee H.
    Ann Surg Oncol; 2008 Nov; 15(11):3272-7. PubMed ID: 18712569
    [Abstract] [Full Text] [Related]

  • 2. Promoter methylation of O(6)-methylguanine-DNA-methyltransferase in lung cancer is regulated by p53.
    Lai JC, Cheng YW, Goan YG, Chang JT, Wu TC, Chen CY, Lee H.
    DNA Repair (Amst); 2008 Aug 02; 7(8):1352-63. PubMed ID: 18555750
    [Abstract] [Full Text] [Related]

  • 3. O(6)-Methylguanine-DNA methyltransferase promoter hypermethylation shifts the p53 mutational spectrum in non-small cell lung cancer.
    Wolf P, Hu YC, Doffek K, Sidransky D, Ahrendt SA.
    Cancer Res; 2001 Nov 15; 61(22):8113-7. PubMed ID: 11719438
    [Abstract] [Full Text] [Related]

  • 4. O6-methylguanine-DNA methyltransferase gene: epigenetic silencing and prognostic value in head and neck squamous cell carcinoma.
    Zuo C, Ai L, Ratliff P, Suen JY, Hanna E, Brent TP, Fan CY.
    Cancer Epidemiol Biomarkers Prev; 2004 Jun 15; 13(6):967-75. PubMed ID: 15184253
    [Abstract] [Full Text] [Related]

  • 5. Promoter hypermethylation of the DNA repair gene O(6)-methylguanine-DNA methyltransferase is associated with the presence of G:C to A:T transition mutations in p53 in human colorectal tumorigenesis.
    Esteller M, Risques RA, Toyota M, Capella G, Moreno V, Peinado MA, Baylin SB, Herman JG.
    Cancer Res; 2001 Jun 15; 61(12):4689-92. PubMed ID: 11406538
    [Abstract] [Full Text] [Related]

  • 6. Aberrant promoter methylation in Chinese patients with non-small cell lung cancer: patterns in primary tumors and potential diagnostic application in bronchoalevolar lavage.
    Chan EC, Lam SY, Tsang KW, Lam B, Ho JC, Fu KH, Lam WK, Kwong YL.
    Clin Cancer Res; 2002 Dec 15; 8(12):3741-6. PubMed ID: 12473584
    [Abstract] [Full Text] [Related]

  • 7. Association between MGMT promoter hypermethylation and p53 mutation in glioblastoma.
    Shamsara J, Sharif S, Afsharnezhad S, Lotfi M, Raziee HR, Ghaffarzadegan K, Moradi A, Rahighi S, Behravan J.
    Cancer Invest; 2009 Oct 15; 27(8):825-9. PubMed ID: 19544111
    [Abstract] [Full Text] [Related]

  • 8. MGMT germline polymorphism is associated with somatic MGMT promoter methylation and gene silencing in colorectal cancer.
    Ogino S, Hazra A, Tranah GJ, Kirkner GJ, Kawasaki T, Nosho K, Ohnishi M, Suemoto Y, Meyerhardt JA, Hunter DJ, Fuchs CS.
    Carcinogenesis; 2007 Sep 15; 28(9):1985-90. PubMed ID: 17621591
    [Abstract] [Full Text] [Related]

  • 9. Promoter hypermethylation of the O6-methylguanine-DNA methyltransferase gene: more common in lung adenocarcinomas from never-smokers than smokers and associated with tumor progression.
    Pulling LC, Divine KK, Klinge DM, Gilliland FD, Kang T, Schwartz AG, Bocklage TJ, Belinsky SA.
    Cancer Res; 2003 Aug 15; 63(16):4842-8. PubMed ID: 12941804
    [Abstract] [Full Text] [Related]

  • 10. O6-Methylguanine-DNA methyltransferase hypermethylation modulated by 17beta-estradiol in lung cancer cells.
    Lai JC, Wu JY, Cheng YW, Yeh KT, Wu TC, Chen CY, Lee H.
    Anticancer Res; 2009 Jul 15; 29(7):2535-40. PubMed ID: 19596925
    [Abstract] [Full Text] [Related]

  • 11. Topoisomerase IIalpha gene expression is regulated by the p53 tumor suppressor gene in nonsmall cell lung carcinoma patients.
    Liu D, Huang CL, Kameyama K, Hayashi E, Yamauchi A, Sumitomo S, Yokomise H.
    Cancer; 2002 Apr 15; 94(8):2239-47. PubMed ID: 12001123
    [Abstract] [Full Text] [Related]

  • 12. Tumor progression through epigenetic gene silencing of O(6)-methylguanine-DNA methyltransferase in human biliary tract cancers.
    Koga Y, Kitajima Y, Miyoshi A, Sato K, Kitahara K, Soejima H, Miyazaki K.
    Ann Surg Oncol; 2005 May 15; 12(5):354-63. PubMed ID: 15915369
    [Abstract] [Full Text] [Related]

  • 13. Relevance of MSP assay for the detection of MGMT promoter hypermethylation in glioblastomas.
    Yachi K, Watanabe T, Ohta T, Fukushima T, Yoshino A, Ogino A, Katayama Y, Nagase H.
    Int J Oncol; 2008 Sep 15; 33(3):469-75. PubMed ID: 18695875
    [Abstract] [Full Text] [Related]

  • 14. Careful exclusion of non-neoplastic brain components is required for an appropriate evaluation of O6-methylguanine-DNA methyltransferase status in glioma: relationship between immunohistochemistry and methylation analysis.
    Sasai K, Nodagashira M, Nishihara H, Aoyanagi E, Wang L, Katoh M, Murata J, Ozaki Y, Ito T, Fujimoto S, Kaneko S, Nagashima K, Tanaka S.
    Am J Surg Pathol; 2008 Aug 15; 32(8):1220-7. PubMed ID: 18580490
    [Abstract] [Full Text] [Related]

  • 15. Inactivation of DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation and its relation to p53 mutations in esophageal squamous cell carcinoma.
    Zhang L, Lu W, Miao X, Xing D, Tan W, Lin D.
    Carcinogenesis; 2003 Jun 15; 24(6):1039-44. PubMed ID: 12807758
    [Abstract] [Full Text] [Related]

  • 16. Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is associated with G to A mutations in K-ras in colorectal tumorigenesis.
    Esteller M, Toyota M, Sanchez-Cespedes M, Capella G, Peinado MA, Watkins DN, Issa JP, Sidransky D, Baylin SB, Herman JG.
    Cancer Res; 2000 May 01; 60(9):2368-71. PubMed ID: 10811111
    [Abstract] [Full Text] [Related]

  • 17. [Correlation of aberrant methylation of MGMT gene to MTHFR C677T genetic polymorphisms in esophageal squamous cell carcinoma].
    Xue HC, Wang JM, Xu B, Guo GP, Hua ZL, Zhou Q, Zhu ZH, Ma ZK, Gao J.
    Ai Zheng; 2008 Dec 01; 27(12):1256-62. PubMed ID: 19079989
    [Abstract] [Full Text] [Related]

  • 18. DNA repair gene O6-methylguanine-DNA methyltransferase: promoter hypermethylation associated with decreased expression and G:C to A:T mutations of p53 in brain tumors.
    Yin D, Xie D, Hofmann WK, Zhang W, Asotra K, Wong R, Black KL, Koeffler HP.
    Mol Carcinog; 2003 Jan 01; 36(1):23-31. PubMed ID: 12503076
    [Abstract] [Full Text] [Related]

  • 19. p16(INK4a) and histology-specific methylation of CpG islands by exposure to tobacco smoke in non-small cell lung cancer.
    Kim DH, Nelson HH, Wiencke JK, Zheng S, Christiani DC, Wain JC, Mark EJ, Kelsey KT.
    Cancer Res; 2001 Apr 15; 61(8):3419-24. PubMed ID: 11309302
    [Abstract] [Full Text] [Related]

  • 20. Methylation of the MGMT gene is frequently detected in advanced gastric carcinoma.
    Hibi K, Sakata M, Yokomizo K, Kitamura YH, Sakuraba K, Shirahata A, Goto T, Mizukami H, Saito M, Ishibashi K, Kigawa G, Nemoto H, Sanada Y.
    Anticancer Res; 2009 Dec 15; 29(12):5053-5. PubMed ID: 20044616
    [Abstract] [Full Text] [Related]

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