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157 related items for PubMed ID: 18719356

  • 1. Regulation of autophagy by ceramide-CD95-PERK signaling.
    Park MA, Zhang G, Norris J, Hylemon PB, Fisher PB, Grant S, Dent P.
    Autophagy; 2008 Oct; 4(7):929-31. PubMed ID: 18719356
    [Abstract] [Full Text] [Related]

  • 2. Vorinostat and sorafenib increase ER stress, autophagy and apoptosis via ceramide-dependent CD95 and PERK activation.
    Park MA, Zhang G, Martin AP, Hamed H, Mitchell C, Hylemon PB, Graf M, Rahmani M, Ryan K, Liu X, Spiegel S, Norris J, Fisher PB, Grant S, Dent P.
    Cancer Biol Ther; 2008 Oct; 7(10):1648-62. PubMed ID: 18787411
    [Abstract] [Full Text] [Related]

  • 3. Multiple cyclin kinase inhibitors promote bile acid-induced apoptosis and autophagy in primary hepatocytes via p53-CD95-dependent signaling.
    Zhang G, Park MA, Mitchell C, Walker T, Hamed H, Studer E, Graf M, Rahmani M, Gupta S, Hylemon PB, Fisher PB, Grant S, Dent P.
    J Biol Chem; 2008 Sep 05; 283(36):24343-58. PubMed ID: 18614532
    [Abstract] [Full Text] [Related]

  • 4. MDA-7/IL-24-induced cell killing in malignant renal carcinoma cells occurs by a ceramide/CD95/PERK-dependent mechanism.
    Park MA, Walker T, Martin AP, Allegood J, Vozhilla N, Emdad L, Sarkar D, Rahmani M, Graf M, Yacoub A, Koumenis C, Spiegel S, Curiel DT, Voelkel-Johnson C, Grant S, Fisher PB, Dent P.
    Mol Cancer Ther; 2009 May 05; 8(5):1280-91. PubMed ID: 19417161
    [Abstract] [Full Text] [Related]

  • 5. Cisplatin enhances protein kinase R-like endoplasmic reticulum kinase- and CD95-dependent melanoma differentiation-associated gene-7/interleukin-24-induced killing in ovarian carcinoma cells.
    Yacoub A, Liu R, Park MA, Hamed HA, Dash R, Schramm DN, Sarkar D, Dimitriev IP, Bell JK, Grant S, Farrell NP, Curiel DT, Fisher PB, Dent P.
    Mol Pharmacol; 2010 Feb 05; 77(2):298-310. PubMed ID: 19910452
    [Abstract] [Full Text] [Related]

  • 6. Sorafenib activates CD95 and promotes autophagy and cell death via Src family kinases in gastrointestinal tumor cells.
    Park MA, Reinehr R, Häussinger D, Voelkel-Johnson C, Ogretmen B, Yacoub A, Grant S, Dent P.
    Mol Cancer Ther; 2010 Aug 05; 9(8):2220-31. PubMed ID: 20682655
    [Abstract] [Full Text] [Related]

  • 7. Sorafenib and vorinostat kill colon cancer cells by CD95-dependent and -independent mechanisms.
    Walker T, Mitchell C, Park MA, Yacoub A, Graf M, Rahmani M, Houghton PJ, Voelkel-Johnson C, Grant S, Dent P.
    Mol Pharmacol; 2009 Aug 05; 76(2):342-55. PubMed ID: 19483104
    [Abstract] [Full Text] [Related]

  • 8. BCL-2 family inhibitors enhance histone deacetylase inhibitor and sorafenib lethality via autophagy and overcome blockade of the extrinsic pathway to facilitate killing.
    Martin AP, Park MA, Mitchell C, Walker T, Rahmani M, Thorburn A, Häussinger D, Reinehr R, Grant S, Dent P.
    Mol Pharmacol; 2009 Aug 05; 76(2):327-41. PubMed ID: 19483105
    [Abstract] [Full Text] [Related]

  • 9. Vorinostat and sorafenib increase CD95 activation in gastrointestinal tumor cells through a Ca(2+)-de novo ceramide-PP2A-reactive oxygen species-dependent signaling pathway.
    Park MA, Mitchell C, Zhang G, Yacoub A, Allegood J, Häussinger D, Reinehr R, Larner A, Spiegel S, Fisher PB, Voelkel-Johnson C, Ogretmen B, Grant S, Dent P.
    Cancer Res; 2010 Aug 01; 70(15):6313-24. PubMed ID: 20631069
    [Abstract] [Full Text] [Related]

  • 10. Vorinostat and sorafenib synergistically kill tumor cells via FLIP suppression and CD95 activation.
    Zhang G, Park MA, Mitchell C, Hamed H, Rahmani M, Martin AP, Curiel DT, Yacoub A, Graf M, Lee R, Roberts JD, Fisher PB, Grant S, Dent P.
    Clin Cancer Res; 2008 Sep 01; 14(17):5385-99. PubMed ID: 18765530
    [Abstract] [Full Text] [Related]

  • 11. PERK-dependent regulation of HSP70 expression and the regulation of autophagy.
    Park MA, Curiel DT, Koumenis C, Graf M, Chen CS, Fisher PB, Grant S, Dent P.
    Autophagy; 2008 Apr 01; 4(3):364-7. PubMed ID: 18216498
    [Abstract] [Full Text] [Related]

  • 12. Amplification of CD95 activation by caspase 8-induced endosomal acidification in rat hepatocytes.
    Reinehr R, Sommerfeld A, Keitel V, Grether-Beck S, Haüssinger D.
    J Biol Chem; 2008 Jan 25; 283(4):2211-22. PubMed ID: 18045865
    [Abstract] [Full Text] [Related]

  • 13. Autophagy and protein kinase RNA-like endoplasmic reticulum kinase (PERK)/eukaryotic initiation factor 2 alpha kinase (eIF2α) pathway protect ovarian cancer cells from metformin-induced apoptosis.
    Moon HS, Kim B, Gwak H, Suh DH, Song YS.
    Mol Carcinog; 2016 Apr 25; 55(4):346-56. PubMed ID: 25663310
    [Abstract] [Full Text] [Related]

  • 14. Protein kinase C regulates FADD recruitment and death-inducing signaling complex formation in Fas/CD95-induced apoptosis.
    Gómez-Angelats M, Cidlowski JA.
    J Biol Chem; 2001 Nov 30; 276(48):44944-52. PubMed ID: 11581255
    [Abstract] [Full Text] [Related]

  • 15. Intermittent-Hypoxia-Induced Autophagy Activation Through the ER-Stress-Related PERK/eIF2α/ATF4 Pathway is a Protective Response to Pancreatic β-Cell Apoptosis.
    Song S, Tan J, Miao Y, Sun Z, Zhang Q.
    Cell Physiol Biochem; 2018 Nov 30; 51(6):2955-2971. PubMed ID: 30562747
    [Abstract] [Full Text] [Related]

  • 16. Autophagy induced by deficiency of sphingosine-1-phosphate phosphohydrolase 1 is switched to apoptosis by calpain-mediated autophagy-related gene 5 (Atg5) cleavage.
    Lépine S, Allegood JC, Edmonds Y, Milstien S, Spiegel S.
    J Biol Chem; 2011 Dec 30; 286(52):44380-90. PubMed ID: 22052905
    [Abstract] [Full Text] [Related]

  • 17. CD95(Fas/APO-1) signals ceramide generation independent of the effector stage of apoptosis.
    Grullich C, Sullards MC, Fuks Z, Merrill AH, Kolesnick R.
    J Biol Chem; 2000 Mar 24; 275(12):8650-6. PubMed ID: 10722705
    [Abstract] [Full Text] [Related]

  • 18. ER stress (PERK/eIF2alpha phosphorylation) mediates the polyglutamine-induced LC3 conversion, an essential step for autophagy formation.
    Kouroku Y, Fujita E, Tanida I, Ueno T, Isoai A, Kumagai H, Ogawa S, Kaufman RJ, Kominami E, Momoi T.
    Cell Death Differ; 2007 Feb 24; 14(2):230-9. PubMed ID: 16794605
    [Abstract] [Full Text] [Related]

  • 19. Deoxycholic acid (DCA) causes ligand-independent activation of epidermal growth factor receptor (EGFR) and FAS receptor in primary hepatocytes: inhibition of EGFR/mitogen-activated protein kinase-signaling module enhances DCA-induced apoptosis.
    Qiao L, Studer E, Leach K, McKinstry R, Gupta S, Decker R, Kukreja R, Valerie K, Nagarkatti P, El Deiry W, Molkentin J, Schmidt-Ullrich R, Fisher PB, Grant S, Hylemon PB, Dent P.
    Mol Biol Cell; 2001 Sep 24; 12(9):2629-45. PubMed ID: 11553704
    [Abstract] [Full Text] [Related]

  • 20. The neuro-steroid, 5-androstene 3β,17α diol; induces endoplasmic reticulum stress and autophagy through PERK/eIF2α signaling in malignant glioma cells and transformed fibroblasts.
    Jia W, Loria RM, Park MA, Yacoub A, Dent P, Graf MR.
    Int J Biochem Cell Biol; 2010 Dec 24; 42(12):2019-29. PubMed ID: 20851775
    [Abstract] [Full Text] [Related]

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