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PUBMED FOR HANDHELDS

Journal Abstract Search


748 related items for PubMed ID: 18722181

  • 1. Bax- or Bak-induced mitochondrial fission can be uncoupled from cytochrome C release.
    Sheridan C, Delivani P, Cullen SP, Martin SJ.
    Mol Cell; 2008 Aug 22; 31(4):570-585. PubMed ID: 18722181
    [Abstract] [Full Text] [Related]

  • 2. The BH3 alpha-helical mimic BH3-M6 disrupts Bcl-X(L), Bcl-2, and MCL-1 protein-protein interactions with Bax, Bak, Bad, or Bim and induces apoptosis in a Bax- and Bim-dependent manner.
    Kazi A, Sun J, Doi K, Sung SS, Takahashi Y, Yin H, Rodriguez JM, Becerril J, Berndt N, Hamilton AD, Wang HG, Sebti SM.
    J Biol Chem; 2011 Mar 18; 286(11):9382-92. PubMed ID: 21148306
    [Abstract] [Full Text] [Related]

  • 3. BH3 domains other than Bim and Bid can directly activate Bax/Bak.
    Du H, Wolf J, Schafer B, Moldoveanu T, Chipuk JE, Kuwana T.
    J Biol Chem; 2011 Jan 07; 286(1):491-501. PubMed ID: 21041309
    [Abstract] [Full Text] [Related]

  • 4. Hierarchical regulation of mitochondrion-dependent apoptosis by BCL-2 subfamilies.
    Kim H, Rafiuddin-Shah M, Tu HC, Jeffers JR, Zambetti GP, Hsieh JJ, Cheng EH.
    Nat Cell Biol; 2006 Dec 07; 8(12):1348-58. PubMed ID: 17115033
    [Abstract] [Full Text] [Related]

  • 5. An interconnected hierarchical model of cell death regulation by the BCL-2 family.
    Chen HC, Kanai M, Inoue-Yamauchi A, Tu HC, Huang Y, Ren D, Kim H, Takeda S, Reyna DE, Chan PM, Ganesan YT, Liao CP, Gavathiotis E, Hsieh JJ, Cheng EH.
    Nat Cell Biol; 2015 Oct 07; 17(10):1270-81. PubMed ID: 26344567
    [Abstract] [Full Text] [Related]

  • 6. Opa1-mediated cristae opening is Bax/Bak and BH3 dependent, required for apoptosis, and independent of Bak oligomerization.
    Yamaguchi R, Lartigue L, Perkins G, Scott RT, Dixit A, Kushnareva Y, Kuwana T, Ellisman MH, Newmeyer DD.
    Mol Cell; 2008 Aug 22; 31(4):557-569. PubMed ID: 18691924
    [Abstract] [Full Text] [Related]

  • 7. Apoptosis initiated when BH3 ligands engage multiple Bcl-2 homologs, not Bax or Bak.
    Willis SN, Fletcher JI, Kaufmann T, van Delft MF, Chen L, Czabotar PE, Ierino H, Lee EF, Fairlie WD, Bouillet P, Strasser A, Kluck RM, Adams JM, Huang DC.
    Science; 2007 Feb 09; 315(5813):856-9. PubMed ID: 17289999
    [Abstract] [Full Text] [Related]

  • 8. Activation of mitochondrial protease OMA1 by Bax and Bak promotes cytochrome c release during apoptosis.
    Jiang X, Jiang H, Shen Z, Wang X.
    Proc Natl Acad Sci U S A; 2014 Oct 14; 111(41):14782-7. PubMed ID: 25275009
    [Abstract] [Full Text] [Related]

  • 9. p14(ARF)-induced apoptosis in p53 protein-deficient cells is mediated by BH3-only protein-independent derepression of Bak protein through down-regulation of Mcl-1 and Bcl-xL proteins.
    Müer A, Overkamp T, Gillissen B, Richter A, Pretzsch T, Milojkovic A, Dörken B, Daniel PT, Hemmati P.
    J Biol Chem; 2012 May 18; 287(21):17343-17352. PubMed ID: 22354970
    [Abstract] [Full Text] [Related]

  • 10. The multidomain proapoptotic molecules Bax and Bak are directly activated by heat.
    Pagliari LJ, Kuwana T, Bonzon C, Newmeyer DD, Tu S, Beere HM, Green DR.
    Proc Natl Acad Sci U S A; 2005 Dec 13; 102(50):17975-80. PubMed ID: 16330765
    [Abstract] [Full Text] [Related]

  • 11. BID, BIM, and PUMA are essential for activation of the BAX- and BAK-dependent cell death program.
    Ren D, Tu HC, Kim H, Wang GX, Bean GR, Takeuchi O, Jeffers JR, Zambetti GP, Hsieh JJ, Cheng EH.
    Science; 2010 Dec 03; 330(6009):1390-3. PubMed ID: 21127253
    [Abstract] [Full Text] [Related]

  • 12. Mcl-1 determines the Bax dependency of Nbk/Bik-induced apoptosis.
    Gillissen B, Essmann F, Hemmati PG, Richter A, Richter A, Oztop I, Chinnadurai G, Dörken B, Daniel PT.
    J Cell Biol; 2007 Nov 19; 179(4):701-15. PubMed ID: 18025305
    [Abstract] [Full Text] [Related]

  • 13. Bax/Bak activation in the absence of Bid, Bim, Puma, and p53.
    Zhang J, Huang K, O'Neill KL, Pang X, Luo X.
    Cell Death Dis; 2016 Jun 16; 7(6):e2266. PubMed ID: 27310874
    [Abstract] [Full Text] [Related]

  • 14. Bid chimeras indicate that most BH3-only proteins can directly activate Bak and Bax, and show no preference for Bak versus Bax.
    Hockings C, Anwari K, Ninnis RL, Brouwer J, O'Hely M, Evangelista M, Hinds MG, Czabotar PE, Lee EF, Fairlie WD, Dewson G, Kluck RM.
    Cell Death Dis; 2015 Apr 23; 6(4):e1735. PubMed ID: 25906158
    [Abstract] [Full Text] [Related]

  • 15. BH3 domains of BH3-only proteins differentially regulate Bax-mediated mitochondrial membrane permeabilization both directly and indirectly.
    Kuwana T, Bouchier-Hayes L, Chipuk JE, Bonzon C, Sullivan BA, Green DR, Newmeyer DD.
    Mol Cell; 2005 Feb 18; 17(4):525-35. PubMed ID: 15721256
    [Abstract] [Full Text] [Related]

  • 16. BH3-only proteins target BCL-xL/MCL-1, not BAX/BAK, to initiate apoptosis.
    Huang K, O'Neill KL, Li J, Zhou W, Han N, Pang X, Wu W, Struble L, Borgstahl G, Liu Z, Zhang L, Luo X.
    Cell Res; 2019 Nov 18; 29(11):942-952. PubMed ID: 31551537
    [Abstract] [Full Text] [Related]

  • 17. Mitochondrial permeabilization relies on BH3 ligands engaging multiple prosurvival Bcl-2 relatives, not Bak.
    Uren RT, Dewson G, Chen L, Coyne SC, Huang DC, Adams JM, Kluck RM.
    J Cell Biol; 2007 Apr 23; 177(2):277-87. PubMed ID: 17452531
    [Abstract] [Full Text] [Related]

  • 18. Direct interaction of Bax and Bak proteins with Bcl-2 homology domain 3 (BH3)-only proteins in living cells revealed by fluorescence complementation.
    Vela L, Gonzalo O, Naval J, Marzo I.
    J Biol Chem; 2013 Feb 15; 288(7):4935-46. PubMed ID: 23283967
    [Abstract] [Full Text] [Related]

  • 19. Involvement of proapoptotic molecules Bax and Bak in tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced mitochondrial disruption and apoptosis: differential regulation of cytochrome c and Smac/DIABLO release.
    Kandasamy K, Srinivasula SM, Alnemri ES, Thompson CB, Korsmeyer SJ, Bryant JL, Srivastava RK.
    Cancer Res; 2003 Apr 01; 63(7):1712-21. PubMed ID: 12670926
    [Abstract] [Full Text] [Related]

  • 20. Translocation of a Bak C-terminus mutant from cytosol to mitochondria to mediate cytochrome C release: implications for Bak and Bax apoptotic function.
    Ferrer PE, Frederick P, Gulbis JM, Dewson G, Kluck RM.
    PLoS One; 2012 Apr 01; 7(3):e31510. PubMed ID: 22442658
    [Abstract] [Full Text] [Related]


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