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158 related items for PubMed ID: 18723356

  • 1. Synthesis and pharmacological evaluation of bis-3-(3,4-dichlorophenyl)acrylamide derivatives as glycogen phosphorylase inhibitors.
    Onda K, Shiraki R, Yonetoku Y, Momose K, Katayama N, Orita M, Yamaguchi T, Ohta M, Tsukamoto S.
    Bioorg Med Chem; 2008 Sep 15; 16(18):8627-34. PubMed ID: 18723356
    [Abstract] [Full Text] [Related]

  • 2. Synthesis of 5-chloro-N-aryl-1H-indole-2-carboxamide derivatives as inhibitors of human liver glycogen phosphorylase a.
    Onda K, Suzuki T, Shiraki R, Yonetoku Y, Negoro K, Momose K, Katayama N, Orita M, Yamaguchi T, Ohta M, Tsukamoto S.
    Bioorg Med Chem; 2008 May 15; 16(10):5452-64. PubMed ID: 18434170
    [Abstract] [Full Text] [Related]

  • 3. Acyl ureas as human liver glycogen phosphorylase inhibitors for the treatment of type 2 diabetes.
    Klabunde T, Wendt KU, Kadereit D, Brachvogel V, Burger HJ, Herling AW, Oikonomakos NG, Kosmopoulou MN, Schmoll D, Sarubbi E, von Roedern E, Schönafinger K, Defossa E.
    J Med Chem; 2005 Oct 06; 48(20):6178-93. PubMed ID: 16190745
    [Abstract] [Full Text] [Related]

  • 4. Synthesis and structure-activity relationships of 3-phenyl-2-propenamides as inhibitors of glycogen phosphorylase a.
    Li YH, Coppo FT, Evans KA, Graybill TL, Patel M, Gale J, Li H, Tavares F, Thomson SA.
    Bioorg Med Chem Lett; 2006 Nov 15; 16(22):5892-6. PubMed ID: 16942879
    [Abstract] [Full Text] [Related]

  • 5. Design, synthesis, and pharmacological evaluation of N-bicyclo-5-chloro-1H-indole-2-carboxamide derivatives as potent glycogen phosphorylase inhibitors.
    Onda K, Shiraki R, Ogiyama T, Yokoyama K, Momose K, Katayama N, Orita M, Yamaguchi T, Furutani M, Hamada N, Takeuchi M, Okada M, Ohta M, Tsukamoto S.
    Bioorg Med Chem; 2008 Dec 01; 16(23):10001-12. PubMed ID: 18952447
    [Abstract] [Full Text] [Related]

  • 6. Synthesis and biological evaluation of asiatic acid derivatives as inhibitors of glycogen phosphorylases.
    Zhang L, Chen J, Gong Y, Liu J, Zhang L, Hua W, Sun H.
    Chem Biodivers; 2009 Jun 01; 6(6):864-74. PubMed ID: 19551727
    [Abstract] [Full Text] [Related]

  • 7. Amino acid anthranilamide derivatives as a new class of glycogen phosphorylase inhibitors.
    Evans KA, Li YH, Coppo FT, Graybill TL, Cichy-Knight M, Patel M, Gale J, Li H, Thrall SH, Tew D, Tavares F, Thomson SA, Weiel JE, Boucheron JA, Clancy DC, Epperly AH, Golden PL.
    Bioorg Med Chem Lett; 2008 Jul 15; 18(14):4068-71. PubMed ID: 18554908
    [Abstract] [Full Text] [Related]

  • 8. Identification, synthesis, and characterization of new glycogen phosphorylase inhibitors binding to the allosteric AMP site.
    Kristiansen M, Andersen B, Iversen LF, Westergaard N.
    J Med Chem; 2004 Jul 01; 47(14):3537-45. PubMed ID: 15214781
    [Abstract] [Full Text] [Related]

  • 9. Discovering benzamide derivatives as glycogen phosphorylase inhibitors and their binding site at the enzyme.
    Chen L, Li H, Liu J, Zhang L, Liu H, Jiang H.
    Bioorg Med Chem; 2007 Nov 01; 15(21):6763-74. PubMed ID: 17719791
    [Abstract] [Full Text] [Related]

  • 10. Synthesis and glycogen phosphorylase inhibitor activity of functionalized 1,4-benzodioxanes.
    Czakó Z, Docsa T, Gergely P, Juhász L, Antus S.
    Pharmazie; 2010 Apr 01; 65(4):235-8. PubMed ID: 20432616
    [Abstract] [Full Text] [Related]

  • 11. Advances in glycogen phosphorylase inhibitor design.
    Oikonomakos NG, Somsák L.
    Curr Opin Investig Drugs; 2008 Apr 01; 9(4):379-95. PubMed ID: 18393105
    [Abstract] [Full Text] [Related]

  • 12. Synthesis and evaluation of 3-anilino-quinoxalinones as glycogen phosphorylase inhibitors.
    Dudash J, Zhang Y, Moore JB, Look R, Liang Y, Beavers MP, Conway BR, Rybczynski PJ, Demarest KT.
    Bioorg Med Chem Lett; 2005 Nov 01; 15(21):4790-3. PubMed ID: 16143521
    [Abstract] [Full Text] [Related]

  • 13. Naturally occurring pentacyclic triterpenes as inhibitors of glycogen phosphorylase: synthesis, structure-activity relationships, and X-ray crystallographic studies.
    Wen X, Sun H, Liu J, Cheng K, Zhang P, Zhang L, Hao J, Zhang L, Ni P, Zographos SE, Leonidas DD, Alexacou KM, Gimisis T, Hayes JM, Oikonomakos NG.
    J Med Chem; 2008 Jun 26; 51(12):3540-54. PubMed ID: 18517260
    [Abstract] [Full Text] [Related]

  • 14. Integrated effects of multiple modulators on human liver glycogen phosphorylase a.
    Ercan-Fang N, Gannon MC, Rath VL, Treadway JL, Taylor MR, Nuttall FQ.
    Am J Physiol Endocrinol Metab; 2002 Jul 26; 283(1):E29-37. PubMed ID: 12067839
    [Abstract] [Full Text] [Related]

  • 15. Crystallographic studies on acyl ureas, a new class of glycogen phosphorylase inhibitors, as potential antidiabetic drugs.
    Oikonomakos NG, Kosmopoulou MN, Chrysina ED, Leonidas DD, Kostas ID, Wendt KU, Klabunde T, Defossa E.
    Protein Sci; 2005 Jul 26; 14(7):1760-71. PubMed ID: 15987904
    [Abstract] [Full Text] [Related]

  • 16. Terpenoids. III: Synthesis and biological evaluation of 23-hydroxybetulinic acid derivatives as novel inhibitors of glycogen phosphorylase.
    Zhu P, Bi Y, Xu J, Li Z, Liu J, Zhang L, Ye W, Wu X.
    Bioorg Med Chem Lett; 2009 Dec 15; 19(24):6966-9. PubMed ID: 19889536
    [Abstract] [Full Text] [Related]

  • 17. Synthesis of a C-glucosylated cyclopropylamide and evaluation as a glycogen phosphorylase inhibitor.
    Bertus P, Szymoniak J, Jeanneau E, Docsa T, Gergely P, Praly JP, Vidal S.
    Bioorg Med Chem Lett; 2008 Sep 01; 18(17):4774-8. PubMed ID: 18701279
    [Abstract] [Full Text] [Related]

  • 18. Discovery of a series of indan carboxylic acid glycogen phosphorylase inhibitors.
    Bennett SN, Campbell AD, Hancock A, Johnstone C, Kenny PW, Pickup A, Plowright AT, Selmi N, Simpson I, Stocker A, Whalley DP, Whittamore PR.
    Bioorg Med Chem Lett; 2010 Jun 15; 20(12):3511-4. PubMed ID: 20493691
    [Abstract] [Full Text] [Related]

  • 19. The synthesis and biological evaluation of some caffeic acid amide derivatives: E-2-cyano-(3-substituted phenyl)acrylamides.
    Zhou W, Li HB, Xia CN, Zheng XM, Hu WX.
    Bioorg Med Chem Lett; 2009 Apr 01; 19(7):1861-5. PubMed ID: 19272773
    [Abstract] [Full Text] [Related]

  • 20. Structure based inhibitor design targeting glycogen phosphorylase B. Virtual screening, synthesis, biochemical and biological assessment of novel N-acyl-β-d-glucopyranosylamines.
    Parmenopoulou V, Kantsadi AL, Tsirkone VG, Chatzileontiadou DS, Manta S, Zographos SE, Molfeta C, Archontis G, Agius L, Hayes JM, Leonidas DD, Komiotis D.
    Bioorg Med Chem; 2014 Sep 01; 22(17):4810-25. PubMed ID: 25092521
    [Abstract] [Full Text] [Related]

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