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Journal Abstract Search


195 related items for PubMed ID: 18725544

  • 1. Contribution of down-regulation of intestinal and hepatic cytochrome P450 3A to increased absorption of cyclosporine A in a rat nephrosis model.
    Fujita T, Yasuda S, Kamata Y, Fujita K, Ohtani Y, Kumagai Y, Majima M.
    J Pharmacol Exp Ther; 2008 Nov; 327(2):592-9. PubMed ID: 18725544
    [Abstract] [Full Text] [Related]

  • 2. An antioxidant Trolox restores decreased oral absorption of cyclosporine A after liver ischemia-reperfusion through distinct mechanisms between CYP3A and P-glycoprotein in the small intestine.
    Ikemura K, Inoue K, Mizutani H, Oka H, Iwamoto T, Okuda M.
    Eur J Pharmacol; 2012 Sep 05; 690(1-3):192-201. PubMed ID: 22749977
    [Abstract] [Full Text] [Related]

  • 3. Decreased oral absorption of cyclosporine A after liver ischemia-reperfusion injury in rats: the contribution of CYP3A and P-glycoprotein to the first-pass metabolism in intestinal epithelial cells.
    Ikemura K, Urano K, Matsuda H, Mizutani H, Iwamoto T, Okuda M.
    J Pharmacol Exp Ther; 2009 Jan 05; 328(1):249-55. PubMed ID: 18842703
    [Abstract] [Full Text] [Related]

  • 4. Impact of MDR1 and CYP3A5 on the oral clearance of tacrolimus and tacrolimus-related renal dysfunction in adult living-donor liver transplant patients.
    Fukudo M, Yano I, Yoshimura A, Masuda S, Uesugi M, Hosohata K, Katsura T, Ogura Y, Oike F, Takada Y, Uemoto S, Inui K.
    Pharmacogenet Genomics; 2008 May 05; 18(5):413-23. PubMed ID: 18408564
    [Abstract] [Full Text] [Related]

  • 5. Selective induction of intestinal CYP3A23 by 1alpha,25-dihydroxyvitamin D3 in rats.
    Xu Y, Iwanaga K, Zhou C, Cheesman MJ, Farin F, Thummel KE.
    Biochem Pharmacol; 2006 Jul 28; 72(3):385-92. PubMed ID: 16769037
    [Abstract] [Full Text] [Related]

  • 6. Effects of liver fibrosis on verapamil pharmacokinetics in rats.
    Chen M, Xu D, Hu XL, Wang H.
    Clin Exp Pharmacol Physiol; 2008 Mar 28; 35(3):287-94. PubMed ID: 17973928
    [Abstract] [Full Text] [Related]

  • 7. Comparison of mouse and rat cytochrome P450-mediated metabolism in liver and intestine.
    Martignoni M, Groothuis G, de Kanter R.
    Drug Metab Dispos; 2006 Jun 28; 34(6):1047-54. PubMed ID: 16565172
    [Abstract] [Full Text] [Related]

  • 8. Demonstration of docosahexaenoic acid as a bioavailability enhancer for CYP3A substrates: in vitro and in vivo evidence using cyclosporin in rats.
    Hirunpanich V, Katagi J, Sethabouppha B, Sato H.
    Drug Metab Dispos; 2006 Feb 28; 34(2):305-10. PubMed ID: 16299163
    [Abstract] [Full Text] [Related]

  • 9. Impact of curcumin-induced changes in P-glycoprotein and CYP3A expression on the pharmacokinetics of peroral celiprolol and midazolam in rats.
    Zhang W, Tan TM, Lim LY.
    Drug Metab Dispos; 2007 Jan 28; 35(1):110-5. PubMed ID: 17050652
    [Abstract] [Full Text] [Related]

  • 10. Altered expression of NDST-1 messenger RNA in puromycin aminonucleoside nephrosis.
    Nakayama K, Natori Y, Sato T, Kimura T, Sugiura A, Sato H, Saito T, Ito S, Natori Y.
    J Lab Clin Med; 2004 Feb 28; 143(2):106-14. PubMed ID: 14966466
    [Abstract] [Full Text] [Related]

  • 11. Evidence for cytochrome P450 3A expression and catalytic activity in rat blood lymphocytes.
    Dey A, Yadav S, Dhawan A, Seth PK, Parmar D.
    Life Sci; 2006 Sep 27; 79(18):1729-35. PubMed ID: 16844145
    [Abstract] [Full Text] [Related]

  • 12. In vivo induction of hepatic p-glycoprotein by cyclosporine in the rat.
    Bai S, Liu J, Lu SK, Brunner LJ.
    Res Commun Mol Pathol Pharmacol; 2001 Jul 27; 109(1-2):103-14. PubMed ID: 11458978
    [Abstract] [Full Text] [Related]

  • 13. Hydroxyitraconazole, formed during intestinal first-pass metabolism of itraconazole, controls the time course of hepatic CYP3A inhibition and the bioavailability of itraconazole in rats.
    Quinney SK, Galinsky RE, Jiyamapa-Serna VA, Chen Y, Hamman MA, Hall SD, Kimura RE.
    Drug Metab Dispos; 2008 Jun 27; 36(6):1097-101. PubMed ID: 18339815
    [Abstract] [Full Text] [Related]

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  • 15. Age-related differences in CYP3A expression and activity in the rat liver, intestine, and kidney.
    Warrington JS, Greenblatt DJ, von Moltke LL.
    J Pharmacol Exp Ther; 2004 May 27; 309(2):720-9. PubMed ID: 14742746
    [Abstract] [Full Text] [Related]

  • 16. Faster clearance of omeprazole in rats with acute renal failure induced by uranyl nitrate: contribution of increased expression of hepatic cytochrome P450 (CYP) 3A1 and intestinal CYP1A and 3A subfamilies.
    Lee DY, Jung YS, Shin HS, Lee I, Kim YC, Lee MG.
    J Pharm Pharmacol; 2008 Jul 27; 60(7):843-51. PubMed ID: 18549670
    [Abstract] [Full Text] [Related]

  • 17. Influence of intravenous methylprednisolone pulse treatment on the disposition of ciclosporin and hepatic CYP3A activity in rats.
    Konishi H, Sumi M, Shibata N, Takada K, Minouchi T, Yamaji A.
    J Pharm Pharmacol; 2004 Apr 27; 56(4):477-83. PubMed ID: 15099443
    [Abstract] [Full Text] [Related]

  • 18. Genetic polymorphisms in CYP3A5 and MDR1 genes and their correlations with plasma levels of tacrolimus and cyclosporine in renal transplant recipients.
    Mendes J, Martinho A, Simoes O, Mota A, Breitenfeld L, Pais L.
    Transplant Proc; 2009 Apr 27; 41(3):840-2. PubMed ID: 19376366
    [Abstract] [Full Text] [Related]

  • 19. Role of uroguanylin, a Peptide with natriuretic activity, in rats with experimental nephrotic syndrome.
    Kikuchi M, Fujimoto S, Fukae H, Kinoshita H, Kita T, Nakazato M, Eto T.
    J Am Soc Nephrol; 2005 Feb 27; 16(2):392-7. PubMed ID: 15590761
    [Abstract] [Full Text] [Related]

  • 20. P-glycoprotein and an unstirred water layer barring digoxin absorption in the vascularly perfused rat small intestine preparation: induction studies with pregnenolone-16alpha-carbonitrile.
    Liu S, Tam D, Chen X, Pang KS.
    Drug Metab Dispos; 2006 Sep 27; 34(9):1468-79. PubMed ID: 16751264
    [Abstract] [Full Text] [Related]


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