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375 related items for PubMed ID: 18729351
1. Potent cationic inhibitors of West Nile virus NS2B/NS3 protease with serum stability, cell permeability and antiviral activity. Stoermer MJ, Chappell KJ, Liebscher S, Jensen CM, Gan CH, Gupta PK, Xu WJ, Young PR, Fairlie DP. J Med Chem; 2008 Sep 25; 51(18):5714-21. PubMed ID: 18729351 [Abstract] [Full Text] [Related]
2. Characterization of the West Nile virus protease substrate specificity and inhibitors. Mueller NH, Yon C, Ganesh VK, Padmanabhan R. Int J Biochem Cell Biol; 2007 Sep 25; 39(3):606-14. PubMed ID: 17188926 [Abstract] [Full Text] [Related]
3. West Nile Virus NS2B/NS3 protease as an antiviral target. Chappell KJ, Stoermer MJ, Fairlie DP, Young PR. Curr Med Chem; 2008 Sep 25; 15(27):2771-84. PubMed ID: 18991636 [Abstract] [Full Text] [Related]
4. Structural basis for the activation of flaviviral NS3 proteases from dengue and West Nile virus. Erbel P, Schiering N, D'Arcy A, Renatus M, Kroemer M, Lim SP, Yin Z, Keller TH, Vasudevan SG, Hommel U. Nat Struct Mol Biol; 2006 Apr 25; 13(4):372-3. PubMed ID: 16532006 [Abstract] [Full Text] [Related]
5. Homology modeling and molecular dynamics study of West Nile virus NS3 protease: a molecular basis for the catalytic activity increased by the NS2B cofactor. Zhou H, Singh NJ, Kim KS. Proteins; 2006 Nov 15; 65(3):692-701. PubMed ID: 16972281 [Abstract] [Full Text] [Related]
6. Structure of West Nile virus NS3 protease: ligand stabilization of the catalytic conformation. Robin G, Chappell K, Stoermer MJ, Hu SH, Young PR, Fairlie DP, Martin JL. J Mol Biol; 2009 Feb 06; 385(5):1568-77. PubMed ID: 19059417 [Abstract] [Full Text] [Related]
7. Synthesis and in vitro evaluation of West Nile virus protease inhibitors based on the 2-{6-[2-(5-phenyl-4H-{1,2,4]triazol-3-ylsulfanyl)acetylamino]benzothiazol-2-ylsulfanyl}acetamide scaffold. Samanta S, Lim TL, Lam Y. ChemMedChem; 2013 Jun 06; 8(6):994-1001. PubMed ID: 23619931 [Abstract] [Full Text] [Related]
8. Effects of NS2B-NS3 protease and furin inhibition on West Nile and Dengue virus replication. Kouretova J, Hammamy MZ, Epp A, Hardes K, Kallis S, Zhang L, Hilgenfeld R, Bartenschlager R, Steinmetzer T. J Enzyme Inhib Med Chem; 2017 Dec 06; 32(1):712-721. PubMed ID: 28385094 [Abstract] [Full Text] [Related]
9. Identification of palmatine as an inhibitor of West Nile virus. Jia F, Zou G, Fan J, Yuan Z. Arch Virol; 2010 Aug 06; 155(8):1325-9. PubMed ID: 20496087 [Abstract] [Full Text] [Related]
10. Phosphonate inhibitors of West Nile virus NS2B/NS3 protease. Skoreński M, Milewska A, Pyrć K, Sieńczyk M, Oleksyszyn J. J Enzyme Inhib Med Chem; 2019 Dec 06; 34(1):8-14. PubMed ID: 30362835 [Abstract] [Full Text] [Related]
11. Breathing new life into West Nile virus therapeutics; discovery and study of zafirlukast as an NS2B-NS3 protease inhibitor. Martinez AA, Espinosa BA, Adamek RN, Thomas BA, Chau J, Gonzalez E, Keppetipola N, Salzameda NT. Eur J Med Chem; 2018 Sep 05; 157():1202-1213. PubMed ID: 30193218 [Abstract] [Full Text] [Related]
12. Towards the design of antiviral inhibitors against flaviviruses: the case for the multifunctional NS3 protein from Dengue virus as a target. Lescar J, Luo D, Xu T, Sampath A, Lim SP, Canard B, Vasudevan SG. Antiviral Res; 2008 Nov 05; 80(2):94-101. PubMed ID: 18674567 [Abstract] [Full Text] [Related]
13. Homology modeling and molecular dynamics simulations of Dengue virus NS2B/NS3 protease: insight into molecular interaction. Wichapong K, Pianwanit S, Sippl W, Kokpol S. J Mol Recognit; 2010 Nov 05; 23(3):283-300. PubMed ID: 19693793 [Abstract] [Full Text] [Related]
14. Exploring the binding of peptidic West Nile virus NS2B-NS3 protease inhibitors by NMR. Kang C, Gayen S, Wang W, Severin R, Chen AS, Lim HA, Chia CS, Schüller A, Doan DN, Poulsen A, Hill J, Vasudevan SG, Keller TH. Antiviral Res; 2013 Feb 05; 97(2):137-44. PubMed ID: 23211132 [Abstract] [Full Text] [Related]
15. Competitive inhibition of the dengue virus NS3 serine protease by synthetic peptides representing polyprotein cleavage sites. Chanprapaph S, Saparpakorn P, Sangma C, Niyomrattanakit P, Hannongbua S, Angsuthanasombat C, Katzenmeier G. Biochem Biophys Res Commun; 2005 May 20; 330(4):1237-46. PubMed ID: 15823576 [Abstract] [Full Text] [Related]
16. Functional determinants of NS2B for activation of Japanese encephalitis virus NS3 protease. Lin CW, Huang HD, Shiu SY, Chen WJ, Tsai MH, Huang SH, Wan L, Lin YJ. Virus Res; 2007 Jul 20; 127(1):88-94. PubMed ID: 17467838 [Abstract] [Full Text] [Related]
17. SAR evolution towards potent C-terminal carboxamide peptide inhibitors of Zika virus NS2B-NS3 protease. Colarusso S, Ferrigno F, Ponzi S, Pavone F, Conte I, Abate L, Beghetto E, Missineo A, Amaudrut J, Bresciani A, Paonessa G, Tomei L, Montalbetti C, Bianchi E, Toniatti C, Ontoria JM. Bioorg Med Chem; 2022 Mar 01; 57():116631. PubMed ID: 35123179 [Abstract] [Full Text] [Related]